Gene name: PKH3
Reference locus (S288C): YDR466W
Gene biotype: protein_coding
Description: 3-phosphoinositide dependent protein kinase-1; Serine/threonine-protein kinase PKH3; Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p; yeast Pkh1p and Pkh2p are two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant
Top 10 interactors (score): PKC1 (0.974); YPK1 (0.9); SCH9 (0.895); PKH2 (0.847); PKH1 (0.845); HSP82 (0.825); HSC82 (0.823); YPK2 (0.761); BCK1 (0.753); YPK3 (0.724); TSC11 (0.719); BSC1 (0.712); YDL196W (0.707); MIH1 (0.654); CMD1 (0.65); NCP1 (0.65); RHO1 (0.635); TEP1 (0.606); RHO3 (0.603); RHO4 (0.603)
Homologues (species, bitscore): PDPK1 (Homo sapiens, 251.1); Pdpk1 (Mus musculus, 251.9); pdpk1b (Danio rerio, 243.0); pdpk1 (Xenopus tropicalis, 245.7); Pdk1 (Drosophila melanogaster, 214.9); pdk-1 (Caenorhabditis elegans, 198.0); PDK1 (Arabidopsis thaliana, 216.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1335033-1337738:+ | gene-YDR466W_AKU4011 | rna-NM_001180774.1_AKU4011 | cds-NP_010754.1_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000039.1:210148-212844:+ | gene-YDR466W_BG1 | rna-NM_001180774.1_BG1 | cds-NP_010754.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1366454-1369150:+ | gene-YDR466W_Bruggeman | rna-NM_001180774.1_Bruggeman | cds-NP_010754.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1343598-1346294:+ | gene-YDR466W_CAT1 | rna-NM_001180774.1_CAT1 | cds-NP_010754.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1329338-1332034:+ | gene-YDR466W_CBS1585 | rna-NM_001180774.1_CBS1585 | cds-NP_010754.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1348706-1351402:+ | gene-YDR466W_CBS436 | rna-NM_001180774.1_CBS436 | cds-NP_010754.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1324965-1327661:+ | gene-YDR466W_CBS6412 | rna-NM_001180774.1_CBS6412 | cds-NP_010754.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1347976-1350672:+ | gene-YDR466W_CBS6413 | rna-NM_001180774.1_CBS6413 | cds-NP_010754.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1393817-1396513:+ | gene-YDR466W_CENPK1137D | rna-NM_001180774.1_CENPK1137D | cds-NP_010754.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1338380-1341076:+ | gene-YDR466W_EthanolRed | rna-NM_001180774.1_EthanolRed | cds-NP_010754.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1341933-1344629:+ | gene-YDR466W_FaliES1 | rna-NM_001180774.1_FaliES1 | cds-NP_010754.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000026.1:40190-42886:+ | gene-YDR466W_JAY291 | rna-NM_001180774.1_JAY291 | cds-NP_010754.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1348946-1351642:+ | gene-YDR466W_MUCL30387 | rna-NM_001180774.1_MUCL30387 | cds-NP_010754.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1330968-1333664:+ | gene-YDR466W_MUCL30388 | rna-NM_001180774.1_MUCL30388 | cds-NP_010754.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1320822-1323518:+ | gene-YDR466W_MUCL39482 | rna-NM_001180774.1_MUCL39482 | cds-NP_010754.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1263622-1266318:+ | gene-YDR466W_MUCL42920 | rna-NM_001180774.1_MUCL42920 | cds-NP_010754.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1395044-1397740:+ | gene-YDR466W_NCIM3186 | rna-NM_001180774.1_NCIM3186 | cds-NP_010754.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1334595-1337291:+ | gene-YDR466W_NCYC1407 | rna-NM_001180774.1_NCYC1407 | cds-NP_010754.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1345441-1348137:+ | gene-YDR466W_PE2H3 | rna-NM_001180774.1_PE2H3 | cds-NP_010754.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1351014-1353710:+ | gene-YDR466W_PE2H4 | rna-NM_001180774.1_PE2H4 | cds-NP_010754.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1395121-1397817:+ | gene-YDR466W_S288C | rna-NM_001180774.1_S288C | cds-NP_010754.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:219343-222039:- | gene-YDR466W_SA1 | rna-NM_001180774.1_SA1 | cds-NP_010754.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1346155-1348851:+ | gene-YDR466W_ThermosaccDry | rna-NM_001180774.1_ThermosaccDry | cds-NP_010754.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1361884-1364580:+ | gene-YDR466W_VR1 | rna-NM_001180774.1_VR1 | cds-NP_010754.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:388827-391523:+ | gene-YDR466W_ZTW1 | rna-NM_001180774.1_ZTW1 | cds-NP_010754.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1349225-1351921:+ | gene-YDR466W_Sparadoxus | rna-NM_001180774.1_Sparadoxus | cds-NP_010754.1_Sparadoxus | 88.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |