PKC1 (YBL105C)


Gene profile

Gene name: PKC1
Reference locus (S288C): YBL105C
Gene biotype: protein_coding

Description: Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC)

Top 10 interactors (score): RHO1 (0.999); CDC42 (0.997); RHO2 (0.996); SLG1 (0.996); BCK1 (0.987); PKH2 (0.984); PKH1 (0.979); PKH3 (0.974); SWI4 (0.965); ROM2 (0.959); ASC1 (0.958); ACT1 (0.947); BEM1 (0.946); TOR2 (0.941); MID2 (0.938); LRG1 (0.935); SLT2 (0.926); RHO5 (0.915); RLM1 (0.915); SEC1 (0.912)

Homologues (species, bitscore): PKN2 (Homo sapiens, 374.8); Pkn2 (Mus musculus, 372.9); prkcg (Danio rerio, 376.3); prkcb (Xenopus tropicalis, 370.2); Pkc98E (Drosophila melanogaster, 381.3); pkc-1 (Caenorhabditis elegans, 358.6); S6K2 (Arabidopsis thaliana, 232.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:14138-17593:- gene-YBL105C_AKU4011 rna-NM_001178345.2_AKU4011 cds-NP_009445.2_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000179.1:4862-8317:- gene-YBL105C_BG1 rna-NM_001178345.2_BG1 cds-NP_009445.2_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:14522-17977:- gene-YBL105C_Bruggeman rna-NM_001178345.2_Bruggeman cds-NP_009445.2_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:16728-20183:- gene-YBL105C_CAT1 rna-NM_001178345.2_CAT1 cds-NP_009445.2_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:6209-9664:- gene-YBL105C_CBS1585 rna-NM_001178345.2_CBS1585 cds-NP_009445.2_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:9161-12616:- gene-YBL105C_CBS436 rna-NM_001178345.2_CBS436 cds-NP_009445.2_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:5997-9452:- gene-YBL105C_CBS6412 rna-NM_001178345.2_CBS6412 cds-NP_009445.2_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:12339-15794:- gene-YBL105C_CBS6413 rna-NM_001178345.2_CBS6413 cds-NP_009445.2_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:8173-11628:- gene-YBL105C_CENPK1137D rna-NM_001178345.2_CENPK1137D cds-NP_009445.2_CENPK1137D 99.8 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:28381-31836:- gene-YBL105C_EthanolRed rna-NM_001178345.2_EthanolRed cds-NP_009445.2_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:28513-31968:- gene-YBL105C_FaliES1 rna-NM_001178345.2_FaliES1 cds-NP_009445.2_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000184.1:5555-9010:- gene-YBL105C_JAY291 rna-NM_001178345.2_JAY291 cds-NP_009445.2_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:13665-17120:- gene-YBL105C_MUCL30387 rna-NM_001178345.2_MUCL30387 cds-NP_009445.2_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:13767-17222:- gene-YBL105C_MUCL30388 rna-NM_001178345.2_MUCL30388 cds-NP_009445.2_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:6365-9820:- gene-YBL105C_MUCL39482 rna-NM_001178345.2_MUCL39482 cds-NP_009445.2_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:13004-16459:- gene-YBL105C_MUCL42920 rna-NM_001178345.2_MUCL42920 cds-NP_009445.2_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:14038-17493:- gene-YBL105C_NCIM3186 rna-NM_001178345.2_NCIM3186 cds-NP_009445.2_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:8037-11492:- gene-YBL105C_NCYC1407 rna-NM_001178345.2_NCYC1407 cds-NP_009445.2_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:14345-17800:- gene-YBL105C_PE2H3 rna-NM_001178345.2_PE2H3 cds-NP_009445.2_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:11977-15432:- gene-YBL105C_PE2H4 rna-NM_001178345.2_PE2H4 cds-NP_009445.2_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:14241-17696:- gene-YBL105C_S288C rna-NM_001178345.2_S288C cds-NP_009445.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000004.1:4660-8115:- gene-YBL105C_SA1 rna-NM_001178345.2_SA1 cds-NP_009445.2_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:28475-31930:- gene-YBL105C_ThermosaccDry rna-NM_001178345.2_ThermosaccDry cds-NP_009445.2_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:10690-14145:- gene-YBL105C_VR1 rna-NM_001178345.2_VR1 cds-NP_009445.2_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:5700-9155:- gene-YBL105C_ZTW1 rna-NM_001178345.2_ZTW1 cds-NP_009445.2_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:40636-44091:- gene-YBL105C_Sparadoxus rna-NM_001178345.2_Sparadoxus cds-NP_009445.2_Sparadoxus 90.2 100.0 Verified 1 1 1 False True False False False

Additional files