Gene name: PIS1
Reference locus (S288C): YPR113W
Gene biotype: protein_coding
Description: CDP-diacylglycerol--inositol 3-phosphatidyltransferase; Phosphatidylinositol synthase; required for biosynthesis of phosphatidylinositol, which is a precursor for polyphosphoinositides, sphingolipids, and glycolipid anchors for some of the plasma membrane proteins; Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Top 10 interactors (score): CDS1 (0.998); CHO1 (0.994); PGS1 (0.989); INM1 (0.984); SAC1 (0.98); CRD1 (0.976); STT4 (0.974); INM2 (0.974); PIK1 (0.97); FAB1 (0.946); PLC1 (0.945); VPS34 (0.944); TDA10 (0.94); PSD1 (0.939); INO1 (0.93); LSB6 (0.924); TEP1 (0.914); TOR1 (0.91); YMR1 (0.909); OPI3 (0.906)
Homologues (species, bitscore): CDIPT (Homo sapiens, 149.1); Cdipt (Mus musculus, 147.5); cdipt (Danio rerio, 143.3); cdipt (Xenopus tropicalis, 143.7); Pis (Drosophila melanogaster, 135.2); pisy-1 (Caenorhabditis elegans, 123.2); PIS1 (Arabidopsis thaliana, 132.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:724086-724748:+ | gene-YPR113W_AKU4011 | rna-NM_001184210.1_AKU4011 | cds-NP_015438.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:173090-173752:- | gene-YPR113W_BG1 | rna-NM_001184210.1_BG1 | cds-NP_015438.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:803198-803860:+ | gene-YPR113W_Bruggeman | rna-NM_001184210.1_Bruggeman | cds-NP_015438.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:846399-847061:+ | gene-YPR113W_CAT1 | rna-NM_001184210.1_CAT1 | cds-NP_015438.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:728343-729005:+ | gene-YPR113W_CBS1585 | rna-NM_001184210.1_CBS1585 | cds-NP_015438.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:742642-743304:+ | gene-YPR113W_CBS436 | rna-NM_001184210.1_CBS436 | cds-NP_015438.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:731066-731728:+ | gene-YPR113W_CBS6412 | rna-NM_001184210.1_CBS6412 | cds-NP_015438.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:725790-726452:+ | gene-YPR113W_CBS6413 | rna-NM_001184210.1_CBS6413 | cds-NP_015438.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:752242-752904:+ | gene-YPR113W_CENPK1137D | rna-NM_001184210.1_CENPK1137D | cds-NP_015438.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:1050700-1051362:+ | gene-YPR113W_EthanolRed | rna-NM_001184210.1_EthanolRed | cds-NP_015438.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:730247-730909:+ | gene-YPR113W_FaliES1 | rna-NM_001184210.1_FaliES1 | cds-NP_015438.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000436.1:21010-21672:+ | gene-YPR113W_JAY291 | rna-NM_001184210.1_JAY291 | cds-NP_015438.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:743353-744015:+ | gene-YPR113W_MUCL30387 | rna-NM_001184210.1_MUCL30387 | cds-NP_015438.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:742048-742710:+ | gene-YPR113W_MUCL30388 | rna-NM_001184210.1_MUCL30388 | cds-NP_015438.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:720850-721512:+ | gene-YPR113W_MUCL39482 | rna-NM_001184210.1_MUCL39482 | cds-NP_015438.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:784393-785055:+ | gene-YPR113W_MUCL42920 | rna-NM_001184210.1_MUCL42920 | cds-NP_015438.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:752240-752902:+ | gene-YPR113W_NCIM3186 | rna-NM_001184210.1_NCIM3186 | cds-NP_015438.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:729444-730106:+ | gene-YPR113W_NCYC1407 | rna-NM_001184210.1_NCYC1407 | cds-NP_015438.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:735686-736348:+ | gene-YPR113W_PE2H3 | rna-NM_001184210.1_PE2H3 | cds-NP_015438.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:735334-735996:+ | gene-YPR113W_PE2H4 | rna-NM_001184210.1_PE2H4 | cds-NP_015438.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:752257-752919:+ | gene-YPR113W_S288C | rna-NM_001184210.1_S288C | cds-NP_015438.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000028.1:50371-51033:+ | gene-YPR113W_SA1 | rna-NM_001184210.1_SA1 | cds-NP_015438.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:729692-730354:+ | gene-YPR113W_ThermosaccDry | rna-NM_001184210.1_ThermosaccDry | cds-NP_015438.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:746353-747015:+ | gene-YPR113W_VR1 | rna-NM_001184210.1_VR1 | cds-NP_015438.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:728744-729406:+ | gene-YPR113W_ZTW1 | rna-NM_001184210.1_ZTW1 | cds-NP_015438.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:729700-730362:+ | gene-YPR113W_Sparadoxus | rna-NM_001184210.1_Sparadoxus | cds-NP_015438.1_Sparadoxus | 92.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |