PIM1 (YBL022C)


Gene profile

Gene name: PIM1
Reference locus (S288C): YBL022C
Gene biotype: protein_coding

Description: ATP-dependent Lon protease; involved in degradation of misfolded proteins in mitochondria; required for biogenesis and maintenance of mitochondria; Belongs to the peptidase S16 family

Top 10 interactors (score): YME1 (0.973); HSP60 (0.969); CHD1 (0.964); TSC13 (0.963); DST1 (0.962); AFG3 (0.955); MCX1 (0.945); YTA12 (0.929); MRX6 (0.901); MGE1 (0.898); MDJ1 (0.897); URA3 (0.844); ACO1 (0.844); SSC1 (0.829); HSP78 (0.807); SOD2 (0.773); HSP104 (0.769); PHB2 (0.757); COX6 (0.751); DNM1 (0.727)

Homologues (species, bitscore): LONP1 (Homo sapiens, 788.9); Lonp1 (Mus musculus, 794.7); lonp1 (Danio rerio, 784.3); LONP1 (Xenopus tropicalis, 798.5); Lon (Drosophila melanogaster, 773.5); C34B2.6 (Caenorhabditis elegans, 781.2); LON1 (Arabidopsis thaliana, 780.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:171484-174885:- gene-YBL022C_AKU4011 rna-NM_001178262.1_AKU4011 cds-NP_009531.1_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000179.1:162312-165713:- gene-YBL022C_BG1 rna-NM_001178262.1_BG1 cds-NP_009531.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:172070-175471:- gene-YBL022C_Bruggeman rna-NM_001178262.1_Bruggeman cds-NP_009531.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:174681-178082:- gene-YBL022C_CAT1 rna-NM_001178262.1_CAT1 cds-NP_009531.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:164039-167440:- gene-YBL022C_CBS1585 rna-NM_001178262.1_CBS1585 cds-NP_009531.1_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:172494-175895:- gene-YBL022C_CBS436 rna-NM_001178262.1_CBS436 cds-NP_009531.1_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:262818-266219:- gene-YBL022C_CBS6412 rna-NM_001178262.1_CBS6412 cds-NP_009531.1_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:169609-173010:- gene-YBL022C_CBS6413 rna-NM_001178262.1_CBS6413 cds-NP_009531.1_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:171639-175040:- gene-YBL022C_CENPK1137D rna-NM_001178262.1_CENPK1137D cds-NP_009531.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:299026-302427:- gene-YBL022C_EthanolRed rna-NM_001178262.1_EthanolRed cds-NP_009531.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:186292-189693:- gene-YBL022C_FaliES1 rna-NM_001178262.1_FaliES1 cds-NP_009531.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000421.1:11963-15364:- gene-YBL022C_JAY291 rna-NM_001178262.1_JAY291 cds-NP_009531.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:171927-175328:- gene-YBL022C_MUCL30387 rna-NM_001178262.1_MUCL30387 cds-NP_009531.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:172969-176370:- gene-YBL022C_MUCL30388 rna-NM_001178262.1_MUCL30388 cds-NP_009531.1_MUCL30388 99.9 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:164224-167625:- gene-YBL022C_MUCL39482 rna-NM_001178262.1_MUCL39482 cds-NP_009531.1_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:171499-174900:- gene-YBL022C_MUCL42920 rna-NM_001178262.1_MUCL42920 cds-NP_009531.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:177671-181072:- gene-YBL022C_NCIM3186 rna-NM_001178262.1_NCIM3186 cds-NP_009531.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:165373-168774:- gene-YBL022C_NCYC1407 rna-NM_001178262.1_NCYC1407 cds-NP_009531.1_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:171600-175001:- gene-YBL022C_PE2H3 rna-NM_001178262.1_PE2H3 cds-NP_009531.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:169244-172645:- gene-YBL022C_PE2H4 rna-NM_001178262.1_PE2H4 cds-NP_009531.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:177874-181275:- gene-YBL022C_S288C rna-NM_001178262.1_S288C cds-NP_009531.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000051.1:62595-65996:- gene-YBL022C_SA1 rna-NM_001178262.1_SA1 cds-NP_009531.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:186247-189648:- gene-YBL022C_ThermosaccDry rna-NM_001178262.1_ThermosaccDry cds-NP_009531.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:168413-171814:- gene-YBL022C_VR1 rna-NM_001178262.1_VR1 cds-NP_009531.1_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:162959-166360:- gene-YBL022C_ZTW1 rna-NM_001178262.1_ZTW1 cds-NP_009531.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:197900-201301:- gene-YBL022C_Sparadoxus rna-NM_001178262.1_Sparadoxus cds-NP_009531.1_Sparadoxus 90.7 99.9 Verified 1 1 1 False True False False False

Additional files