PIL1 (YGR086C)


Gene profile

Gene name: PIL1
Reference locus (S288C): YGR086C
Gene biotype: protein_coding

Description: Sphingolipid long chain base-responsive protein PIL1; Eisosome core component; eisosomes are large immobile cell cortex structures associated with endocytosis; detected in phosphorylated state in mitochondria; phosphorylated on Thr233 upon Pkc1p hyperactivation in a Slt2p MAPK-dependent fashion; null mutant shows activation of Pkc1p/Ypk1p stress resistance pathways; member of BAR domain family; protein increases in abundance and relocalizes from plasma membrane to cytoplasm upon DNA replication stress

Top 10 interactors (score): LSP1 (0.995); PKH1 (0.989); MRP8 (0.977); EIS1 (0.974); SEG1 (0.967); NCE102 (0.966); SUR7 (0.957); PKH2 (0.936); INP52 (0.9); RVS167 (0.89); YGR130C (0.889); ABP1 (0.887); INP51 (0.854); SLM1 (0.853); ACT1 (0.839); SCS2 (0.813); PMA1 (0.803); MSC3 (0.789); SEG2 (0.761); FHN1 (0.759)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:633777-634796:- gene-YGR086C_AKU4011 rna-NM_001181215.3_AKU4011 cds-NP_011600.3_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000173.1:69575-70594:- gene-YGR086C_BG1 rna-NM_001181215.3_BG1 cds-NP_011600.3_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:635715-636734:- gene-YGR086C_Bruggeman rna-NM_001181215.3_Bruggeman cds-NP_011600.3_Bruggeman 99.5 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:634156-635175:- gene-YGR086C_CAT1 rna-NM_001181215.3_CAT1 cds-NP_011600.3_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:634740-635759:- gene-YGR086C_CBS1585 rna-NM_001181215.3_CBS1585 cds-NP_011600.3_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:636404-637423:- gene-YGR086C_CBS436 rna-NM_001181215.3_CBS436 cds-NP_011600.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:626433-627452:- gene-YGR086C_CBS6412 rna-NM_001181215.3_CBS6412 cds-NP_011600.3_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:631376-632395:- gene-YGR086C_CBS6413 rna-NM_001181215.3_CBS6413 cds-NP_011600.3_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:649277-650296:- gene-YGR086C_CENPK1137D rna-NM_001181215.3_CENPK1137D cds-NP_011600.3_CENPK1137D 99.6 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:621320-622339:- gene-YGR086C_EthanolRed rna-NM_001181215.3_EthanolRed cds-NP_011600.3_EthanolRed 99.5 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:625167-626186:- gene-YGR086C_FaliES1 rna-NM_001181215.3_FaliES1 cds-NP_011600.3_FaliES1 99.4 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000396.1:50364-51383:+ gene-YGR086C_JAY291 rna-NM_001181215.3_JAY291 cds-NP_011600.3_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:632421-633440:- gene-YGR086C_MUCL30387 rna-NM_001181215.3_MUCL30387 cds-NP_011600.3_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:635766-636785:- gene-YGR086C_MUCL30388 rna-NM_001181215.3_MUCL30388 cds-NP_011600.3_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:630468-631487:- gene-YGR086C_MUCL39482 rna-NM_001181215.3_MUCL39482 cds-NP_011600.3_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:640759-641778:- gene-YGR086C_MUCL42920 rna-NM_001181215.3_MUCL42920 cds-NP_011600.3_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:649598-650617:- gene-YGR086C_NCIM3186 rna-NM_001181215.3_NCIM3186 cds-NP_011600.3_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:625157-626176:- gene-YGR086C_NCYC1407 rna-NM_001181215.3_NCYC1407 cds-NP_011600.3_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:627845-628864:- gene-YGR086C_PE2H3 rna-NM_001181215.3_PE2H3 cds-NP_011600.3_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:632965-633984:- gene-YGR086C_PE2H4 rna-NM_001181215.3_PE2H4 cds-NP_011600.3_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:649598-650617:- gene-YGR086C_S288C rna-NM_001181215.3_S288C cds-NP_011600.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000015.1:76169-77188:- gene-YGR086C_SA1 rna-NM_001181215.3_SA1 cds-NP_011600.3_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:644841-645860:- gene-YGR086C_ThermosaccDry rna-NM_001181215.3_ThermosaccDry cds-NP_011600.3_ThermosaccDry 99.5 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:742037-743056:- gene-YGR086C_VR1 rna-NM_001181215.3_VR1 cds-NP_011600.3_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000015.1:99793-100812:- gene-YGR086C_ZTW1 rna-NM_001181215.3_ZTW1 cds-NP_011600.3_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:635046-636065:- gene-YGR086C_Sparadoxus rna-NM_001181215.3_Sparadoxus cds-NP_011600.3_Sparadoxus 93.9 100.0 Verified 1 1 1 False True False False False

Additional files