Gene name: PIK1
Reference locus (S288C): YNL267W
Gene biotype: protein_coding
Description: Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosphatidylinositol-4,5-biphosphate; may control cytokinesis through the actin cytoskeleton; may control nonselective autophagy and mitophagy through trafficking of Atg9p; Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily
Top 10 interactors (score): FRQ1 (0.999); SAC1 (0.998); LSB6 (0.998); MSS4 (0.996); ARF1 (0.991); FAB1 (0.99); YPT31 (0.99); PLC1 (0.983); STT4 (0.983); INP53 (0.978); SEC7 (0.977); PIS1 (0.97); INP52 (0.967); SEC14 (0.964); YPT32 (0.961); VPS34 (0.946); INP51 (0.943); ARF2 (0.939); KES1 (0.937); TEP1 (0.934)
Homologues (species, bitscore): PI4KB (Homo sapiens, 302.4); Pi4kb (Mus musculus, 297.0); pi4kb (Danio rerio, 292.0); ENSXETP00000014915 (Xenopus tropicalis, 268.5); fwd (Drosophila melanogaster, 297.4); pifk-1 (Caenorhabditis elegans, 255.4); PI-4KBETA1 (Arabidopsis thaliana, 257.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:134714-137914:+ | gene-YNL267W_AKU4011 | rna-NM_001183105.1_AKU4011 | cds-NP_014132.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:38673-41873:+ | gene-YNL267W_BG1 | rna-NM_001183105.1_BG1 | cds-NP_014132.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:144478-147678:+ | gene-YNL267W_Bruggeman | rna-NM_001183105.1_Bruggeman | cds-NP_014132.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:151834-155034:+ | gene-YNL267W_CAT1 | rna-NM_001183105.1_CAT1 | cds-NP_014132.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:135114-138314:+ | gene-YNL267W_CBS1585 | rna-NM_001183105.1_CBS1585 | cds-NP_014132.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:130152-133352:+ | gene-YNL267W_CBS436 | rna-NM_001183105.1_CBS436 | cds-NP_014132.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:131526-134726:+ | gene-YNL267W_CBS6412 | rna-NM_001183105.1_CBS6412 | cds-NP_014132.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:131807-135007:+ | gene-YNL267W_CBS6413 | rna-NM_001183105.1_CBS6413 | cds-NP_014132.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:134759-137959:+ | gene-YNL267W_CENPK1137D | rna-NM_001183105.1_CENPK1137D | cds-NP_014132.1_CENPK1137D | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:132360-135560:+ | gene-YNL267W_EthanolRed | rna-NM_001183105.1_EthanolRed | cds-NP_014132.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:127097-130297:+ | gene-YNL267W_FaliES1 | rna-NM_001183105.1_FaliES1 | cds-NP_014132.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000082.1:38271-41471:+ | gene-YNL267W_JAY291 | rna-NM_001183105.1_JAY291 | cds-NP_014132.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:140015-143151:+ | gene-YNL267W_MUCL30387 | rna-NM_001183105.1_MUCL30387 | cds-NP_014132.1_MUCL30387 | 96.6 | 97.8 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:138083-141283:+ | gene-YNL267W_MUCL30388 | rna-NM_001183105.1_MUCL30388 | cds-NP_014132.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:132604-135804:+ | gene-YNL267W_MUCL39482 | rna-NM_001183105.1_MUCL39482 | cds-NP_014132.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:134813-138013:+ | gene-YNL267W_MUCL42920 | rna-NM_001183105.1_MUCL42920 | cds-NP_014132.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:140847-144047:+ | gene-YNL267W_NCIM3186 | rna-NM_001183105.1_NCIM3186 | cds-NP_014132.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:134705-137905:+ | gene-YNL267W_NCYC1407 | rna-NM_001183105.1_NCYC1407 | cds-NP_014132.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:131607-134807:+ | gene-YNL267W_PE2H3 | rna-NM_001183105.1_PE2H3 | cds-NP_014132.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:130995-134195:+ | gene-YNL267W_PE2H4 | rna-NM_001183105.1_PE2H4 | cds-NP_014132.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:140878-144078:+ | gene-YNL267W_S288C | rna-NM_001183105.1_S288C | cds-NP_014132.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000034.1:38341-41541:+ | gene-YNL267W_SA1 | rna-NM_001183105.1_SA1 | cds-NP_014132.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:127954-131154:+ | gene-YNL267W_ThermosaccDry | rna-NM_001183105.1_ThermosaccDry | cds-NP_014132.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:146806-150006:+ | gene-YNL267W_VR1 | rna-NM_001183105.1_VR1 | cds-NP_014132.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:38290-41490:+ | gene-YNL267W_ZTW1 | rna-NM_001183105.1_ZTW1 | cds-NP_014132.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:138169-141357:+ | gene-YNL267W_Sparadoxus | rna-NM_001183105.1_Sparadoxus | cds-NP_014132.1_Sparadoxus | 90.6 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |