PIH1 (YHR034C)


Gene profile

Gene name: PIH1
Reference locus (S288C): YHR034C
Gene biotype: protein_coding

Description: Protein interacting with Hsp90 1; Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1); R2TP complex interacts with Hsp90 (Hsp82p and Hsc82p) to mediate assembly large protein complexes such as box C/D snoRNPs and RNA polymerase II

Top 10 interactors (score): RVB1 (0.999); TAH1 (0.999); RVB2 (0.999); NOP58 (0.998); HSC82 (0.987); HSP82 (0.979); RSA1 (0.976); NOP56 (0.972); SNU13 (0.97); NOP1 (0.945); TTI1 (0.925); TEL2 (0.911); BCD1 (0.893); PRP31 (0.884); SHQ1 (0.844); RRP9 (0.839); NHP2 (0.829); STI1 (0.825); GOT1 (0.788); SRP40 (0.787)

Homologues (species, bitscore): PIH1D1 (Homo sapiens, 59.7); Pih1d1 (Mus musculus, 53.9); Nop17l (Drosophila melanogaster, 55.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:165235-166269:- gene-YHR034C_AKU4011 rna-NM_001179164.1_AKU4011 cds-NP_011899.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000053.1:85434-86474:- gene-YHR034C_BG1 rna-NM_001179164.1_BG1 cds-NP_011899.1_BG1 98.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:172668-173708:- gene-YHR034C_Bruggeman rna-NM_001179164.1_Bruggeman cds-NP_011899.1_Bruggeman 98.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:167053-168093:- gene-YHR034C_CAT1 rna-NM_001179164.1_CAT1 cds-NP_011899.1_CAT1 98.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:165607-166641:- gene-YHR034C_CBS1585 rna-NM_001179164.1_CBS1585 cds-NP_011899.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:159836-160876:- gene-YHR034C_CBS436 rna-NM_001179164.1_CBS436 cds-NP_011899.1_CBS436 98.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:164569-165603:- gene-YHR034C_CBS6412 rna-NM_001179164.1_CBS6412 cds-NP_011899.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:165414-166448:- gene-YHR034C_CBS6413 rna-NM_001179164.1_CBS6413 cds-NP_011899.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:170226-171260:- gene-YHR034C_CENPK1137D rna-NM_001179164.1_CENPK1137D cds-NP_011899.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:164739-165773:- gene-YHR034C_EthanolRed rna-NM_001179164.1_EthanolRed cds-NP_011899.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:165718-166752:- gene-YHR034C_FaliES1 rna-NM_001179164.1_FaliES1 cds-NP_011899.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000273.1:14896-15936:+ gene-YHR034C_JAY291 rna-NM_001179164.1_JAY291 cds-NP_011899.1_JAY291 98.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:171743-172777:- gene-YHR034C_MUCL30387 rna-NM_001179164.1_MUCL30387 cds-NP_011899.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:172207-173247:- gene-YHR034C_MUCL30388 rna-NM_001179164.1_MUCL30388 cds-NP_011899.1_MUCL30388 98.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:164644-165678:- gene-YHR034C_MUCL39482 rna-NM_001179164.1_MUCL39482 cds-NP_011899.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:171297-172337:- gene-YHR034C_MUCL42920 rna-NM_001179164.1_MUCL42920 cds-NP_011899.1_MUCL42920 98.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:176847-177881:- gene-YHR034C_NCIM3186 rna-NM_001179164.1_NCIM3186 cds-NP_011899.1_NCIM3186 98.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005270.1:164507-165541:- gene-YHR034C_NCYC1407 rna-NM_001179164.1_NCYC1407 cds-NP_011899.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:166825-167871:- gene-YHR034C_PE2H3 rna-NM_001179164.1_PE2H3 cds-NP_011899.1_PE2H3 98.1 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:174266-175312:- gene-YHR034C_PE2H4 rna-NM_001179164.1_PE2H4 cds-NP_011899.1_PE2H4 98.1 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:176965-177999:- gene-YHR034C_S288C rna-NM_001179164.1_S288C cds-NP_011899.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000014.1:180571-181611:+ gene-YHR034C_SA1 rna-NM_001179164.1_SA1 cds-NP_011899.1_SA1 98.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:166807-167841:- gene-YHR034C_ThermosaccDry rna-NM_001179164.1_ThermosaccDry cds-NP_011899.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:173322-174362:- gene-YHR034C_VR1 rna-NM_001179164.1_VR1 cds-NP_011899.1_VR1 98.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:158358-159392:- gene-YHR034C_ZTW1 rna-NM_001179164.1_ZTW1 cds-NP_011899.1_ZTW1 99.4 100.0 Verified 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:164441-165463:- gene-YHR034C_Sparadoxus rna-NM_001179164.1_Sparadoxus cds-NP_011899.1_Sparadoxus 85.1 98.7 Verified 1 1 1 False True False False False

Additional files