PIB1 (YDR313C)


Gene profile

Gene name: PIB1
Reference locus (S288C): YDR313C
Gene biotype: protein_coding

Description: E3 ubiquitin-protein ligase PIB1; RING-type ubiquitin ligase of the endosomal and vacuolar membranes; binds phosphatidylinositol(3)-phosphate; contains a FYVE finger domain

Top 10 interactors (score): PIB2 (0.896); VPS27 (0.852); TUL1 (0.829); ATG8 (0.811); PEP7 (0.763); SSH4 (0.699); SLM2 (0.694); TOM1 (0.675); RDS2 (0.644); SYN8 (0.617); RSP5 (0.614); INA1 (0.605); RPT2 (0.604); KTR4 (0.593); PEP5 (0.578); VPS34 (0.575); UBP3 (0.574); RMA1 (0.571); YML082W (0.565); CAB5 (0.563)

Homologues (species, bitscore): FYCO1 (Homo sapiens, 66.2); Eea1 (Mus musculus, 58.5); LOC565649 (Danio rerio, 63.9); wdfy3 (Xenopus tropicalis, 55.5); rush (Drosophila melanogaster, 65.9); lst-2 (Caenorhabditis elegans, 58.5); FAB1A (Arabidopsis thaliana, 58.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:1041207-1042067:- gene-YDR313C_AKU4011 rna-NM_001180621.1_AKU4011 cds-NP_010599.1_AKU4011 99.1 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:89491-90351:+ gene-YDR313C_BG1 rna-NM_001180621.1_BG1 cds-NP_010599.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1068473-1069333:- gene-YDR313C_Bruggeman rna-NM_001180621.1_Bruggeman cds-NP_010599.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1055481-1056341:- gene-YDR313C_CAT1 rna-NM_001180621.1_CAT1 cds-NP_010599.1_CAT1 99.0 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1035652-1036512:- gene-YDR313C_CBS1585 rna-NM_001180621.1_CBS1585 cds-NP_010599.1_CBS1585 99.1 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1054021-1054881:- gene-YDR313C_CBS436 rna-NM_001180621.1_CBS436 cds-NP_010599.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1032339-1033199:- gene-YDR313C_CBS6412 rna-NM_001180621.1_CBS6412 cds-NP_010599.1_CBS6412 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1053572-1054432:- gene-YDR313C_CBS6413 rna-NM_001180621.1_CBS6413 cds-NP_010599.1_CBS6413 99.1 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1087857-1088717:- gene-YDR313C_CENPK1137D rna-NM_001180621.1_CENPK1137D cds-NP_010599.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:216749-217609:- gene-YDR313C_EthanolRed rna-NM_001180621.1_EthanolRed cds-NP_010599.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1047964-1048824:- gene-YDR313C_FaliES1 rna-NM_001180621.1_FaliES1 cds-NP_010599.1_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000386.1:464-1324:- gene-YDR313C_JAY291 rna-NM_001180621.1_JAY291 cds-NP_010599.1_JAY291 99.0 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1053984-1054844:- gene-YDR313C_MUCL30387 rna-NM_001180621.1_MUCL30387 cds-NP_010599.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1041059-1041919:- gene-YDR313C_MUCL30388 rna-NM_001180621.1_MUCL30388 cds-NP_010599.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1027459-1028319:- gene-YDR313C_MUCL39482 rna-NM_001180621.1_MUCL39482 cds-NP_010599.1_MUCL39482 99.1 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:968603-969463:- gene-YDR313C_MUCL42920 rna-NM_001180621.1_MUCL42920 cds-NP_010599.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1089142-1090002:- gene-YDR313C_NCIM3186 rna-NM_001180621.1_NCIM3186 cds-NP_010599.1_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1040751-1041611:- gene-YDR313C_NCYC1407 rna-NM_001180621.1_NCYC1407 cds-NP_010599.1_NCYC1407 99.1 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1051739-1052599:- gene-YDR313C_PE2H3 rna-NM_001180621.1_PE2H3 cds-NP_010599.1_PE2H3 99.0 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1057324-1058184:- gene-YDR313C_PE2H4 rna-NM_001180621.1_PE2H4 cds-NP_010599.1_PE2H4 99.0 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1089219-1090079:- gene-YDR313C_S288C rna-NM_001180621.1_S288C cds-NP_010599.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000025.1:65965-66825:- gene-YDR313C_SA1 rna-NM_001180621.1_SA1 cds-NP_010599.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1052237-1053097:- gene-YDR313C_ThermosaccDry rna-NM_001180621.1_ThermosaccDry cds-NP_010599.1_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:1068156-1069016:- gene-YDR313C_VR1 rna-NM_001180621.1_VR1 cds-NP_010599.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:96353-97213:- gene-YDR313C_ZTW1 rna-NM_001180621.1_ZTW1 cds-NP_010599.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1047779-1048651:- gene-YDR313C_Sparadoxus rna-NM_001180621.1_Sparadoxus cds-NP_010599.1_Sparadoxus 87.9 99.8 Verified 1 1 1 False True False False False

Additional files