Gene name: PHS1
Reference locus (S288C): YJL097W
Gene biotype: protein_coding
Description: Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase PHS1; Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane; involved in elongation of very long-chain fatty acids; evolutionarily conserved, similar to mammalian PTPLA and PTPLB; involved in sphingolipid biosynthesis and protein trafficking
Top 10 interactors (score): TSC13 (0.999); IFA38 (0.995); ELO2 (0.977); ELO3 (0.972); OLE1 (0.97); ELO1 (0.968); ACC1 (0.783); DPL1 (0.755); LCB4 (0.746); ROT1 (0.744); YDR193W (0.717); TVP23 (0.697); YML007C-A (0.672); YJL175W (0.671); TSC10 (0.665); LCB5 (0.665); GPI13 (0.649); UIP3 (0.645); YAR028W (0.645); YBR219C (0.644)
Homologues (species, bitscore): PTPLB (Homo sapiens, 106.3); Ptplb (Mus musculus, 107.5); ptplb (Danio rerio, 102.8); ptplb (Xenopus tropicalis, 102.4); CG6746 (Drosophila melanogaster, 109.0); hpo-8 (Caenorhabditis elegans, 122.5); PAS2 (Arabidopsis thaliana, 107.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:228320-228973:+ | gene-YJL097W_AKU4011 | rna-NM_001181530.1_AKU4011 | cds-NP_012438.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:385481-386134:- | gene-YJL097W_BG1 | rna-NM_001181530.1_BG1 | cds-NP_012438.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:239757-240410:+ | gene-YJL097W_Bruggeman | rna-NM_001181530.1_Bruggeman | cds-NP_012438.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:244659-245312:+ | gene-YJL097W_CAT1 | rna-NM_001181530.1_CAT1 | cds-NP_012438.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:239981-240634:+ | gene-YJL097W_CBS1585 | rna-NM_001181530.1_CBS1585 | cds-NP_012438.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:258080-258733:+ | gene-YJL097W_CBS436 | rna-NM_001181530.1_CBS436 | cds-NP_012438.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:229078-229731:+ | gene-YJL097W_CBS6412 | rna-NM_001181530.1_CBS6412 | cds-NP_012438.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:230433-231086:+ | gene-YJL097W_CBS6413 | rna-NM_001181530.1_CBS6413 | cds-NP_012438.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:228044-228697:+ | gene-YJL097W_CENPK1137D | rna-NM_001181530.1_CENPK1137D | cds-NP_012438.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:232167-232820:+ | gene-YJL097W_EthanolRed | rna-NM_001181530.1_EthanolRed | cds-NP_012438.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:243744-244397:+ | gene-YJL097W_FaliES1 | rna-NM_001181530.1_FaliES1 | cds-NP_012438.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000138.1:41360-42013:+ | gene-YJL097W_JAY291 | rna-NM_001181530.1_JAY291 | cds-NP_012438.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:242027-242680:+ | gene-YJL097W_MUCL30387 | rna-NM_001181530.1_MUCL30387 | cds-NP_012438.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:238102-238755:+ | gene-YJL097W_MUCL30388 | rna-NM_001181530.1_MUCL30388 | cds-NP_012438.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:232738-233391:+ | gene-YJL097W_MUCL39482 | rna-NM_001181530.1_MUCL39482 | cds-NP_012438.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:238934-239587:+ | gene-YJL097W_MUCL42920 | rna-NM_001181530.1_MUCL42920 | cds-NP_012438.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:245570-246223:+ | gene-YJL097W_NCIM3186 | rna-NM_001181530.1_NCIM3186 | cds-NP_012438.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:231427-232080:+ | gene-YJL097W_NCYC1407 | rna-NM_001181530.1_NCYC1407 | cds-NP_012438.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:243786-244439:+ | gene-YJL097W_PE2H3 | rna-NM_001181530.1_PE2H3 | cds-NP_012438.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:243430-244083:+ | gene-YJL097W_PE2H4 | rna-NM_001181530.1_PE2H4 | cds-NP_012438.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:245591-246244:+ | gene-YJL097W_S288C | rna-NM_001181530.1_S288C | cds-NP_012438.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000003.1:41300-41953:+ | gene-YJL097W_SA1 | rna-NM_001181530.1_SA1 | cds-NP_012438.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:237153-237806:+ | gene-YJL097W_ThermosaccDry | rna-NM_001181530.1_ThermosaccDry | cds-NP_012438.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:237565-238218:+ | gene-YJL097W_VR1 | rna-NM_001181530.1_VR1 | cds-NP_012438.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:218514-219167:+ | gene-YJL097W_ZTW1 | rna-NM_001181530.1_ZTW1 | cds-NP_012438.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:242602-243255:+ | gene-YJL097W_Sparadoxus | rna-NM_001181530.1_Sparadoxus | cds-NP_012438.1_Sparadoxus | 89.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |