Gene name: PHO92
Reference locus (S288C): YDR374C
Gene biotype: protein_coding
Description: Methylated RNA-binding protein 1; Posttranscriptional regulator of phosphate metabolism; facilitates PHO4 mRNA degradation by interacting with Pop2p; regulates PHO4 mRNA stability by binding to PHO4's 3'UTR in a phosphate-dependent manner; contains highly conserved YTH (YT521-B Homology) domain that exhibits RNA-binding activity; human homolog YTHDF2 can complement yeast null mutant
Top 10 interactors (score): RRP6 (0.929); MTR4 (0.873); PAP1 (0.856); SGN1 (0.836); CDC39 (0.78); IME4 (0.752); CAF40 (0.748); MOT2 (0.747); POP2 (0.739); NGL1 (0.727); CCR4 (0.727); SLZ1 (0.727); YHR202W (0.715); YDL211C (0.699); GMC2 (0.695); YLR410W-B (0.694); YMR147W (0.693); YDR018C (0.691); ECM11 (0.683); KAR4 (0.683)
Homologues (species, bitscore): YTHDF2 (Homo sapiens, 122.5); Ythdf3 (Mus musculus, 122.5); yth2 (Danio rerio, 121.7); ythdf3 (Xenopus tropicalis, 121.7); CG6422 (Drosophila melanogaster, 124.8); ECT10 (Arabidopsis thaliana, 130.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1163616-1164536:- | gene-YDR374C_AKU4011 | rna-NM_001180682.3_AKU4011 | cds-NP_010662.3_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000039.1:42166-43086:- | gene-YDR374C_BG1 | rna-NM_001180682.3_BG1 | cds-NP_010662.3_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1194249-1195169:- | gene-YDR374C_Bruggeman | rna-NM_001180682.3_Bruggeman | cds-NP_010662.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1172860-1173780:- | gene-YDR374C_CAT1 | rna-NM_001180682.3_CAT1 | cds-NP_010662.3_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1158333-1159253:- | gene-YDR374C_CBS1585 | rna-NM_001180682.3_CBS1585 | cds-NP_010662.3_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1176917-1177837:- | gene-YDR374C_CBS436 | rna-NM_001180682.3_CBS436 | cds-NP_010662.3_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1154594-1155514:- | gene-YDR374C_CBS6412 | rna-NM_001180682.3_CBS6412 | cds-NP_010662.3_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1176484-1177404:- | gene-YDR374C_CBS6413 | rna-NM_001180682.3_CBS6413 | cds-NP_010662.3_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1222126-1223046:- | gene-YDR374C_CENPK1137D | rna-NM_001180682.3_CENPK1137D | cds-NP_010662.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1168017-1168937:- | gene-YDR374C_EthanolRed | rna-NM_001180682.3_EthanolRed | cds-NP_010662.3_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1171300-1172220:- | gene-YDR374C_FaliES1 | rna-NM_001180682.3_FaliES1 | cds-NP_010662.3_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000057.1:18853-19773:+ | gene-YDR374C_JAY291 | rna-NM_001180682.3_JAY291 | cds-NP_010662.3_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1177567-1178487:- | gene-YDR374C_MUCL30387 | rna-NM_001180682.3_MUCL30387 | cds-NP_010662.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1160171-1161091:- | gene-YDR374C_MUCL30388 | rna-NM_001180682.3_MUCL30388 | cds-NP_010662.3_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1149867-1150787:- | gene-YDR374C_MUCL39482 | rna-NM_001180682.3_MUCL39482 | cds-NP_010662.3_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1092299-1093219:- | gene-YDR374C_MUCL42920 | rna-NM_001180682.3_MUCL42920 | cds-NP_010662.3_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1223397-1224317:- | gene-YDR374C_NCIM3186 | rna-NM_001180682.3_NCIM3186 | cds-NP_010662.3_NCIM3186 | 93.7 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1163538-1164458:- | gene-YDR374C_NCYC1407 | rna-NM_001180682.3_NCYC1407 | cds-NP_010662.3_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1173967-1174887:- | gene-YDR374C_PE2H3 | rna-NM_001180682.3_PE2H3 | cds-NP_010662.3_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1179552-1180472:- | gene-YDR374C_PE2H4 | rna-NM_001180682.3_PE2H4 | cds-NP_010662.3_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1223474-1224394:- | gene-YDR374C_S288C | rna-NM_001180682.3_S288C | cds-NP_010662.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000072.1:42247-43167:- | gene-YDR374C_SA1 | rna-NM_001180682.3_SA1 | cds-NP_010662.3_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1175581-1176501:- | gene-YDR374C_ThermosaccDry | rna-NM_001180682.3_ThermosaccDry | cds-NP_010662.3_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:602930-603850:- | gene-YDR374C_VR1 | rna-NM_001180682.3_VR1 | cds-NP_010662.3_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:218414-219334:- | gene-YDR374C_ZTW1 | rna-NM_001180682.3_ZTW1 | cds-NP_010662.3_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1170149-1171069:- | gene-YDR374C_Sparadoxus | rna-NM_001180682.3_Sparadoxus | cds-NP_010662.3_Sparadoxus | 88.2 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |