PHO89 (YBR296C)


Gene profile

Gene name: PHO89
Reference locus (S288C): YBR296C
Gene biotype: protein_coding

Description: Solute carrier family 20 (sodium-dependent phosphate transporter); Phosphate permease PHO89; Plasma membrane Na+/Pi cotransporter; active in early growth phase; similar to phosphate transporters of Neurospora crassa; transcription regulated by inorganic phosphate concentrations and Pho4p; mutations in related human transporter genes hPit1 and hPit2 are associated with hyperphosphatemia-induced calcification of vascular tissue and familial idiopathic basal ganglia calcification

Top 10 interactors (score): PHO84 (0.996); PHO87 (0.957); PHO90 (0.951); PHO11 (0.942); PHO91 (0.942); PHO81 (0.93); PHO12 (0.911); SPL2 (0.898); GDE1 (0.895); PHO4 (0.874); PHO8 (0.843); PHM6 (0.81); NHA1 (0.788); VTC4 (0.771); PHO80 (0.77); PHO85 (0.766); VTC3 (0.764); ENA1 (0.761); YLH47 (0.753); TRK2 (0.732)

Homologues (species, bitscore): SLC20A1 (Homo sapiens, 245.4); Slc20a1 (Mus musculus, 243.0); slc20a1b (Danio rerio, 250.8); slc20a2 (Xenopus tropicalis, 240.0); CG42575 (Drosophila melanogaster, 226.5); B0222.3 (Caenorhabditis elegans, 252.3); PHT2;1 (Arabidopsis thaliana, 167.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:781134-782858:- gene-YBR296C_AKU4011 rna-NM_001178644.1_AKU4011 cds-NP_009855.1_AKU4011 99.0 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000001.1:198-1922:- gene-YBR296C_BG1 rna-NM_001178644.1_BG1 cds-NP_009855.1_BG1 99.9 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:782203-783927:- gene-YBR296C_Bruggeman rna-NM_001178644.1_Bruggeman cds-NP_009855.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:785956-787680:- gene-YBR296C_CAT1 rna-NM_001178644.1_CAT1 cds-NP_009855.1_CAT1 99.9 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:772701-774425:- gene-YBR296C_CBS1585 rna-NM_001178644.1_CBS1585 cds-NP_009855.1_CBS1585 99.0 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:779084-780808:- gene-YBR296C_CBS436 rna-NM_001178644.1_CBS436 cds-NP_009855.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:867250-868974:- gene-YBR296C_CBS6412 rna-NM_001178644.1_CBS6412 cds-NP_009855.1_CBS6412 99.0 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:778729-780453:- gene-YBR296C_CBS6413 rna-NM_001178644.1_CBS6413 cds-NP_009855.1_CBS6413 99.0 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:790697-792421:- gene-YBR296C_CENPK1137D rna-NM_001178644.1_CENPK1137D cds-NP_009855.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:904293-906017:- gene-YBR296C_EthanolRed rna-NM_001178644.1_EthanolRed cds-NP_009855.1_EthanolRed 99.0 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:797626-799350:- gene-YBR296C_FaliES1 rna-NM_001178644.1_FaliES1 cds-NP_009855.1_FaliES1 99.0 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000067.1:4947-6671:+ gene-YBR296C_JAY291 rna-NM_001178644.1_JAY291 cds-NP_009855.1_JAY291 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:784272-785996:- gene-YBR296C_MUCL30387 rna-NM_001178644.1_MUCL30387 cds-NP_009855.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:801604-803328:- gene-YBR296C_MUCL30388 rna-NM_001178644.1_MUCL30388 cds-NP_009855.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:771008-772732:- gene-YBR296C_MUCL39482 rna-NM_001178644.1_MUCL39482 cds-NP_009855.1_MUCL39482 99.0 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:780814-782538:- gene-YBR296C_MUCL42920 rna-NM_001178644.1_MUCL42920 cds-NP_009855.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:796595-798319:- gene-YBR296C_NCIM3186 rna-NM_001178644.1_NCIM3186 cds-NP_009855.1_NCIM3186 99.8 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:772895-774619:- gene-YBR296C_NCYC1407 rna-NM_001178644.1_NCYC1407 cds-NP_009855.1_NCYC1407 99.0 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:795983-797707:- gene-YBR296C_PE2H3 rna-NM_001178644.1_PE2H3 cds-NP_009855.1_PE2H3 99.9 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:793659-795383:- gene-YBR296C_PE2H4 rna-NM_001178644.1_PE2H4 cds-NP_009855.1_PE2H4 99.9 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:796798-798522:- gene-YBR296C_S288C rna-NM_001178644.1_S288C cds-NP_009855.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000019.1:151939-153663:- gene-YBR296C_SA1 rna-NM_001178644.1_SA1 cds-NP_009855.1_SA1 99.9 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:796618-798342:- gene-YBR296C_ThermosaccDry rna-NM_001178644.1_ThermosaccDry cds-NP_009855.1_ThermosaccDry 99.0 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:776681-778405:- gene-YBR296C_VR1 rna-NM_001178644.1_VR1 cds-NP_009855.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:769319-771043:- gene-YBR296C_ZTW1 rna-NM_001178644.1_ZTW1 cds-NP_009855.1_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:813008-814732:- gene-YBR296C_Sparadoxus rna-NM_001178644.1_Sparadoxus cds-NP_009855.1_Sparadoxus 91.0 100.0 Verified 1 1 1 False True False False False

Additional files