PHO85 (YPL031C)


Gene profile

Gene name: PHO85
Reference locus (S288C): YPL031C
Gene biotype: protein_coding

Description: Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation

Top 10 interactors (score): PCL1 (0.999); PHO4 (0.999); PCL8 (0.999); CKS1 (0.999); PCL6 (0.999); PHO81 (0.999); PCL10 (0.999); PHO80 (0.999); PCL5 (0.998); PCL7 (0.997); POL30 (0.996); CLB1 (0.996); PCL2 (0.995); CDC6 (0.994); MIH1 (0.993); PCL9 (0.991); GCN4 (0.985); SWE1 (0.984); CLN2 (0.983); CLB2 (0.981)

Homologues (species, bitscore): CDK2 (Homo sapiens, 342.4); Cdk5 (Mus musculus, 331.3); cdk2 (Danio rerio, 348.6); cdk16 (Xenopus tropicalis, 317.4); Cdk5 (Drosophila melanogaster, 312.4); cdk-5 (Caenorhabditis elegans, 316.2); CDC2 (Arabidopsis thaliana, 316.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:463510-464529:- gene-YPL031C_AKU4011 rna-NM_001183845.1_AKU4011 cds-NP_015294.1_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:432851-433870:+ gene-YPL031C_BG1 rna-NM_001183845.1_BG1 cds-NP_015294.1_BG1 99.6 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:540471-541490:- gene-YPL031C_Bruggeman rna-NM_001183845.1_Bruggeman cds-NP_015294.1_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:580151-581170:- gene-YPL031C_CAT1 rna-NM_001183845.1_CAT1 cds-NP_015294.1_CAT1 99.7 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:467580-468599:- gene-YPL031C_CBS1585 rna-NM_001183845.1_CBS1585 cds-NP_015294.1_CBS1585 99.7 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:481718-482737:- gene-YPL031C_CBS436 rna-NM_001183845.1_CBS436 cds-NP_015294.1_CBS436 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:471772-472791:- gene-YPL031C_CBS6412 rna-NM_001183845.1_CBS6412 cds-NP_015294.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:464132-465151:- gene-YPL031C_CBS6413 rna-NM_001183845.1_CBS6413 cds-NP_015294.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:491986-493005:- gene-YPL031C_CENPK1137D rna-NM_001183845.1_CENPK1137D cds-NP_015294.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:461870-462889:- gene-YPL031C_EthanolRed rna-NM_001183845.1_EthanolRed cds-NP_015294.1_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:469700-470719:- gene-YPL031C_FaliES1 rna-NM_001183845.1_FaliES1 cds-NP_015294.1_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000283.1:78307-79326:- gene-YPL031C_JAY291 rna-NM_001183845.1_JAY291 cds-NP_015294.1_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:481419-482438:- gene-YPL031C_MUCL30387 rna-NM_001183845.1_MUCL30387 cds-NP_015294.1_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:480527-481546:- gene-YPL031C_MUCL30388 rna-NM_001183845.1_MUCL30388 cds-NP_015294.1_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:460896-461915:- gene-YPL031C_MUCL39482 rna-NM_001183845.1_MUCL39482 cds-NP_015294.1_MUCL39482 99.7 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:519522-520541:- gene-YPL031C_MUCL42920 rna-NM_001183845.1_MUCL42920 cds-NP_015294.1_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:492001-493020:- gene-YPL031C_NCIM3186 rna-NM_001183845.1_NCIM3186 cds-NP_015294.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:468174-469193:- gene-YPL031C_NCYC1407 rna-NM_001183845.1_NCYC1407 cds-NP_015294.1_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:474820-475839:- gene-YPL031C_PE2H3 rna-NM_001183845.1_PE2H3 cds-NP_015294.1_PE2H3 99.7 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:474435-475454:- gene-YPL031C_PE2H4 rna-NM_001183845.1_PE2H4 cds-NP_015294.1_PE2H4 99.7 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:492018-493037:- gene-YPL031C_S288C rna-NM_001183845.1_S288C cds-NP_015294.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000029.1:34876-35895:- gene-YPL031C_SA1 rna-NM_001183845.1_SA1 cds-NP_015294.1_SA1 99.7 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:469499-470518:- gene-YPL031C_ThermosaccDry rna-NM_001183845.1_ThermosaccDry cds-NP_015294.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:484398-485417:- gene-YPL031C_VR1 rna-NM_001183845.1_VR1 cds-NP_015294.1_VR1 99.7 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:468791-469810:- gene-YPL031C_ZTW1 rna-NM_001183845.1_ZTW1 cds-NP_015294.1_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:468766-469786:- gene-YPL031C_Sparadoxus rna-NM_001183845.1_Sparadoxus cds-NP_015294.1_Sparadoxus 92.5 100.0 Verified 1 1 1 False True False False False

Additional files