PHO84 (YML123C)


Gene profile

Gene name: PHO84
Reference locus (S288C): YML123C
Gene biotype: protein_coding

Description: High-affinity inorganic phosphate (Pi) transporter; also low-affinity manganese transporter; regulated by Pho4p and Spt7p; mutation confers resistance to arsenate; exit from the ER during maturation requires Pho86p; cells overexpressing Pho84p accumulate heavy metals but do not develop symptoms of metal toxicity

Top 10 interactors (score): SPL2 (0.996); PHO89 (0.996); PHO90 (0.983); VTC3 (0.981); PHO11 (0.979); PHO87 (0.976); PHO91 (0.97); VTC1 (0.97); VTC4 (0.968); PHO81 (0.962); PHO4 (0.961); PHO80 (0.951); PHO12 (0.949); PHO5 (0.938); PHO86 (0.899); PHO85 (0.888); RRP6 (0.865); PHO3 (0.815); SMF2 (0.776); ZRT1 (0.768)

Homologues (species, bitscore): SVOP (Homo sapiens, 67.4); Slc22a13 (Mus musculus, 68.2); sv2 (Danio rerio, 80.5); slc22a13 (Xenopus tropicalis, 60.5); Orct2 (Drosophila melanogaster, 63.5); Y82E9BR.16 (Caenorhabditis elegans, 62.8); PHT1;7 (Arabidopsis thaliana, 314.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:17740-19500:- gene-YML123C_AKU4011 rna-NM_001182486.1_AKU4011 cds-NP_013583.1_AKU4011 98.8 99.8 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000201.1:456757-458517:+ gene-YML123C_BG1 rna-NM_001182486.1_BG1 cds-NP_013583.1_BG1 98.4 99.8 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:23991-25754:- gene-YML123C_Bruggeman rna-NM_001182486.1_Bruggeman cds-NP_013583.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:25561-27321:- gene-YML123C_CAT1 rna-NM_001182486.1_CAT1 cds-NP_013583.1_CAT1 98.5 99.8 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:17739-19499:- gene-YML123C_CBS1585 rna-NM_001182486.1_CBS1585 cds-NP_013583.1_CBS1585 98.8 99.8 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:23751-25514:- gene-YML123C_CBS436 rna-NM_001182486.1_CBS436 cds-NP_013583.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:18502-20262:- gene-YML123C_CBS6412 rna-NM_001182486.1_CBS6412 cds-NP_013583.1_CBS6412 98.8 99.8 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:16966-18726:- gene-YML123C_CBS6413 rna-NM_001182486.1_CBS6413 cds-NP_013583.1_CBS6413 98.8 99.8 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:18554-20317:- gene-YML123C_CENPK1137D rna-NM_001182486.1_CENPK1137D cds-NP_013583.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005483.1:18253-20013:- gene-YML123C_EthanolRed rna-NM_001182486.1_EthanolRed cds-NP_013583.1_EthanolRed 98.6 99.8 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:18530-20290:- gene-YML123C_FaliES1 rna-NM_001182486.1_FaliES1 cds-NP_013583.1_FaliES1 98.6 99.8 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000345.1:69941-71701:+ gene-YML123C_JAY291 rna-NM_001182486.1_JAY291 cds-NP_013583.1_JAY291 98.6 99.8 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:22013-23776:- gene-YML123C_MUCL30387 rna-NM_001182486.1_MUCL30387 cds-NP_013583.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:25685-27448:- gene-YML123C_MUCL30388 rna-NM_001182486.1_MUCL30388 cds-NP_013583.1_MUCL30388 99.2 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:17793-19553:- gene-YML123C_MUCL39482 rna-NM_001182486.1_MUCL39482 cds-NP_013583.1_MUCL39482 98.8 99.8 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:21459-23222:- gene-YML123C_MUCL42920 rna-NM_001182486.1_MUCL42920 cds-NP_013583.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:23991-25754:- gene-YML123C_NCIM3186 rna-NM_001182486.1_NCIM3186 cds-NP_013583.1_NCIM3186 98.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:18549-20309:- gene-YML123C_NCYC1407 rna-NM_001182486.1_NCYC1407 cds-NP_013583.1_NCYC1407 98.8 99.8 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:23939-25699:- gene-YML123C_PE2H3 rna-NM_001182486.1_PE2H3 cds-NP_013583.1_PE2H3 98.6 99.8 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:23877-25637:- gene-YML123C_PE2H4 rna-NM_001182486.1_PE2H4 cds-NP_013583.1_PE2H4 98.6 99.8 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:24037-25800:- gene-YML123C_S288C rna-NM_001182486.1_S288C cds-NP_013583.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000054.1:15856-17616:- gene-YML123C_SA1 rna-NM_001182486.1_SA1 cds-NP_013583.1_SA1 98.5 99.8 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:17828-19588:- gene-YML123C_ThermosaccDry rna-NM_001182486.1_ThermosaccDry cds-NP_013583.1_ThermosaccDry 98.6 99.8 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:22232-23992:- gene-YML123C_VR1 rna-NM_001182486.1_VR1 cds-NP_013583.1_VR1 98.5 99.8 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000026.1:17018-18778:- gene-YML123C_ZTW1 rna-NM_001182486.1_ZTW1 cds-NP_013583.1_ZTW1 98.8 99.8 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:28914-30674:- gene-YML123C_Sparadoxus rna-NM_001182486.1_Sparadoxus cds-NP_013583.1_Sparadoxus 95.9 99.8 Verified 1 1 1 False True False False False

Additional files