Gene name: PHO81
Reference locus (S288C): YGR233C
Gene biotype: protein_coding
Description: Phosphate system positive regulatory protein PHO81; Cyclin-dependent kinase (CDK) inhibitor; regulates Pho80p-Pho85p and Pcl7p-Pho85p cyclin-CDK complexes in response to phosphate levels; inhibitory activity for Pho80p-Pho85p requires myo-D-inositol heptakisphosphate (IP7) generated by Vip1p; relative distribution to the nucleus increases upon DNA replication stress
Top 10 interactors (score): PHO80 (0.999); PHO85 (0.999); PHO4 (0.971); PHO84 (0.962); PHO89 (0.93); VTC3 (0.929); SYG1 (0.926); PHO5 (0.916); SEC24 (0.901); SFB2 (0.901); SFB3 (0.9); VTC2 (0.889); PHO87 (0.868); SIT4 (0.868); PHO8 (0.866); PHO12 (0.857); PHO90 (0.852); CYR1 (0.847); CDC53 (0.845); HRT1 (0.835)
Homologues (species, bitscore): ANK1 (Homo sapiens, 84.3); Ank1 (Mus musculus, 84.0); ank2b (Danio rerio, 91.3); ank2 (Xenopus tropicalis, 89.7); nompC (Drosophila melanogaster, 72.4); unc-44 (Caenorhabditis elegans, 71.2); AT1G63010 (Arabidopsis thaliana, 60.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:920076-923615:- | gene-YGR233C_AKU4011 | rna-NM_001181362.3_AKU4011 | cds-NP_011749.3_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:200194-203727:- | gene-YGR233C_BG1 | rna-NM_001181362.3_BG1 | cds-NP_011749.3_BG1 | 98.6 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:927675-931208:- | gene-YGR233C_Bruggeman | rna-NM_001181362.3_Bruggeman | cds-NP_011749.3_Bruggeman | 98.9 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:926371-930511:- | gene-YGR233C_CAT1 | rna-NM_001181362.3_CAT1 | cds-NP_011749.3_CAT1 | 84.9 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:922940-926479:- | gene-YGR233C_CBS1585 | rna-NM_001181362.3_CBS1585 | cds-NP_011749.3_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:926601-930134:- | gene-YGR233C_CBS436 | rna-NM_001181362.3_CBS436 | cds-NP_011749.3_CBS436 | 98.6 | 99.9 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:913810-917349:- | gene-YGR233C_CBS6412 | rna-NM_001181362.3_CBS6412 | cds-NP_011749.3_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:919869-923408:- | gene-YGR233C_CBS6413 | rna-NM_001181362.3_CBS6413 | cds-NP_011749.3_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:954321-957857:- | gene-YGR233C_CENPK1137D | rna-NM_001181362.3_CENPK1137D | cds-NP_011749.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:908079-911618:- | gene-YGR233C_EthanolRed | rna-NM_001181362.3_EthanolRed | cds-NP_011749.3_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:912714-916253:- | gene-YGR233C_FaliES1 | rna-NM_001181362.3_FaliES1 | cds-NP_011749.3_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000076.1:114028-117561:+ | gene-YGR233C_JAY291 | rna-NM_001181362.3_JAY291 | cds-NP_011749.3_JAY291 | 98.7 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:925591-929124:- | gene-YGR233C_MUCL30387 | rna-NM_001181362.3_MUCL30387 | cds-NP_011749.3_MUCL30387 | 98.8 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:924845-928387:- | gene-YGR233C_MUCL30388 | rna-NM_001181362.3_MUCL30388 | cds-NP_011749.3_MUCL30388 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:918015-921554:- | gene-YGR233C_MUCL39482 | rna-NM_001181362.3_MUCL39482 | cds-NP_011749.3_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:936566-940105:- | gene-YGR233C_MUCL42920 | rna-NM_001181362.3_MUCL42920 | cds-NP_011749.3_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:954674-958210:- | gene-YGR233C_NCIM3186 | rna-NM_001181362.3_NCIM3186 | cds-NP_011749.3_NCIM3186 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:913672-917211:- | gene-YGR233C_NCYC1407 | rna-NM_001181362.3_NCYC1407 | cds-NP_011749.3_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:938872-942405:- | gene-YGR233C_PE2H3 | rna-NM_001181362.3_PE2H3 | cds-NP_011749.3_PE2H3 | 98.6 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:943711-947244:- | gene-YGR233C_PE2H4 | rna-NM_001181362.3_PE2H4 | cds-NP_011749.3_PE2H4 | 98.6 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:954674-958210:- | gene-YGR233C_S288C | rna-NM_001181362.3_S288C | cds-NP_011749.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000045.1:43281-46814:+ | gene-YGR233C_SA1 | rna-NM_001181362.3_SA1 | cds-NP_011749.3_SA1 | 98.6 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:933225-936764:- | gene-YGR233C_ThermosaccDry | rna-NM_001181362.3_ThermosaccDry | cds-NP_011749.3_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:1038014-1042054:- | gene-YGR233C_VR1 | rna-NM_001181362.3_VR1 | cds-NP_011749.3_VR1 | 86.4 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:234657-238196:- | gene-YGR233C_ZTW1 | rna-NM_001181362.3_ZTW1 | cds-NP_011749.3_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:925422-929027:- | gene-YGR233C_Sparadoxus | rna-NM_001181362.3_Sparadoxus | cds-NP_011749.3_Sparadoxus | 88.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |