Gene name: PHO8
Reference locus (S288C): YDR481C
Gene biotype: protein_coding
Description: Repressible vacuolar alkaline phosphatase; regulated by levels of Pi and by Pho4p, Pho9p, Pho80p, Pho81p and Pho85p; dephosphorylates phosphotyrosyl peptides; contributes to NAD+ metabolism by producing nicotinamide riboside from NMN
Top 10 interactors (score): PHO11 (0.942); PHO5 (0.941); PHO12 (0.93); THI21 (0.911); THI20 (0.911); THI6 (0.9); THI80 (0.9); FOL1 (0.9); FOL2 (0.9); PHO13 (0.893); PEP4 (0.867); PHO81 (0.866); PHO89 (0.843); PRC1 (0.831); LTP1 (0.83); PHO3 (0.819); PEP12 (0.807); DIA3 (0.8); VAC8 (0.791); PNP1 (0.784)
Homologues (species, bitscore): ALPPL2 (Homo sapiens, 144.4); Alpl (Mus musculus, 135.6); alpi.2 (Danio rerio, 145.6); alpi.1 (Xenopus tropicalis, 145.2); CG8147 (Drosophila melanogaster, 143.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1358470-1360170:- | gene-YDR481C_AKU4011 | rna-NM_001180789.3_AKU4011 | cds-NP_010769.3_AKU4011 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000073.1:81-1781:- | gene-YDR481C_BG1 | rna-NM_001180789.3_BG1 | cds-NP_010769.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1389877-1391577:- | gene-YDR481C_Bruggeman | rna-NM_001180789.3_Bruggeman | cds-NP_010769.3_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1367025-1368725:- | gene-YDR481C_CAT1 | rna-NM_001180789.3_CAT1 | cds-NP_010769.3_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1352769-1354469:- | gene-YDR481C_CBS1585 | rna-NM_001180789.3_CBS1585 | cds-NP_010769.3_CBS1585 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1372127-1373827:- | gene-YDR481C_CBS436 | rna-NM_001180789.3_CBS436 | cds-NP_010769.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1348393-1350093:- | gene-YDR481C_CBS6412 | rna-NM_001180789.3_CBS6412 | cds-NP_010769.3_CBS6412 | 98.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1371404-1373104:- | gene-YDR481C_CBS6413 | rna-NM_001180789.3_CBS6413 | cds-NP_010769.3_CBS6413 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1417246-1418946:- | gene-YDR481C_CENPK1137D | rna-NM_001180789.3_CENPK1137D | cds-NP_010769.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1361809-1363509:- | gene-YDR481C_EthanolRed | rna-NM_001180789.3_EthanolRed | cds-NP_010769.3_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1365362-1367062:- | gene-YDR481C_FaliES1 | rna-NM_001180789.3_FaliES1 | cds-NP_010769.3_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000026.1:63619-65319:- | gene-YDR481C_JAY291 | rna-NM_001180789.3_JAY291 | cds-NP_010769.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1372368-1374068:- | gene-YDR481C_MUCL30387 | rna-NM_001180789.3_MUCL30387 | cds-NP_010769.3_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1354395-1356095:- | gene-YDR481C_MUCL30388 | rna-NM_001180789.3_MUCL30388 | cds-NP_010769.3_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1344254-1345954:- | gene-YDR481C_MUCL39482 | rna-NM_001180789.3_MUCL39482 | cds-NP_010769.3_MUCL39482 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1287043-1288743:- | gene-YDR481C_MUCL42920 | rna-NM_001180789.3_MUCL42920 | cds-NP_010769.3_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1418473-1420173:- | gene-YDR481C_NCIM3186 | rna-NM_001180789.3_NCIM3186 | cds-NP_010769.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1358023-1359723:- | gene-YDR481C_NCYC1407 | rna-NM_001180789.3_NCYC1407 | cds-NP_010769.3_NCYC1407 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1368884-1370584:- | gene-YDR481C_PE2H3 | rna-NM_001180789.3_PE2H3 | cds-NP_010769.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1374458-1376158:- | gene-YDR481C_PE2H4 | rna-NM_001180789.3_PE2H4 | cds-NP_010769.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1418550-1420250:- | gene-YDR481C_S288C | rna-NM_001180789.3_S288C | cds-NP_010769.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:196896-198596:+ | gene-YDR481C_SA1 | rna-NM_001180789.3_SA1 | cds-NP_010769.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1369584-1371284:- | gene-YDR481C_ThermosaccDry | rna-NM_001180789.3_ThermosaccDry | cds-NP_010769.3_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1385329-1387029:- | gene-YDR481C_VR1 | rna-NM_001180789.3_VR1 | cds-NP_010769.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:412250-413950:- | gene-YDR481C_ZTW1 | rna-NM_001180789.3_ZTW1 | cds-NP_010769.3_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1372357-1374057:- | gene-YDR481C_Sparadoxus | rna-NM_001180789.3_Sparadoxus | cds-NP_010769.3_Sparadoxus | 89.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |