PHO4 (YFR034C)


Gene profile

Gene name: PHO4
Reference locus (S288C): YFR034C
Gene biotype: protein_coding

Description: Phosphate system positive regulatory protein PHO4; Basic helix-loop-helix (bHLH) transcription factor of the myc-family; activates transcription cooperatively with Pho2p in response to phosphate limitation; binding to 'CACGTG' motif is regulated by chromatin restriction, competitive binding of Cbf1p to the same DNA binding motif and cooperation with Pho2p; function is regulated by phosphorylation at multiple sites and by phosphate availability

Top 10 interactors (score): PHO85 (0.999); PHO80 (0.999); PSE1 (0.998); PHO2 (0.995); PHO81 (0.971); MSN5 (0.966); PHO84 (0.961); CBF1 (0.909); PHO5 (0.891); PHO89 (0.874); PHO87 (0.861); PHO90 (0.833); SPL2 (0.827); SPT15 (0.81); UGP1 (0.78); VTC4 (0.763); PHO12 (0.76); PHO11 (0.748); PHO8 (0.748); TYE7 (0.745)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005300.1:215181-216119:- gene-YFR034C_AKU4011 rna-NM_001179999.1_AKU4011 cds-NP_116692.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000071.1:44931-45869:+ gene-YFR034C_BG1 rna-NM_001179999.1_BG1 cds-NP_116692.1_BG1 99.1 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005508.1:218849-219787:- gene-YFR034C_Bruggeman rna-NM_001179999.1_Bruggeman cds-NP_116692.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005524.1:220803-221741:- gene-YFR034C_CAT1 rna-NM_001179999.1_CAT1 cds-NP_116692.1_CAT1 99.2 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005364.1:216673-217611:- gene-YFR034C_CBS1585 rna-NM_001179999.1_CBS1585 cds-NP_116692.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005348.1:189629-190567:- gene-YFR034C_CBS436 rna-NM_001179999.1_CBS436 cds-NP_116692.1_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005332.1:215750-216688:- gene-YFR034C_CBS6412 rna-NM_001179999.1_CBS6412 cds-NP_116692.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005316.1:218408-219346:- gene-YFR034C_CBS6413 rna-NM_001179999.1_CBS6413 cds-NP_116692.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001527.1:221117-222055:- gene-YFR034C_CENPK1137D rna-NM_001179999.1_CENPK1137D cds-NP_116692.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005476.1:214287-215225:- gene-YFR034C_EthanolRed rna-NM_001179999.1_EthanolRed cds-NP_116692.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005540.1:215938-216876:- gene-YFR034C_FaliES1 rna-NM_001179999.1_FaliES1 cds-NP_116692.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000453.1:19065-20003:- gene-YFR034C_JAY291 rna-NM_001179999.1_JAY291 cds-NP_116692.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005412.1:219280-220218:- gene-YFR034C_MUCL30387 rna-NM_001179999.1_MUCL30387 cds-NP_116692.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005444.1:214777-215715:- gene-YFR034C_MUCL30388 rna-NM_001179999.1_MUCL30388 cds-NP_116692.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005284.1:214591-215529:- gene-YFR034C_MUCL39482 rna-NM_001179999.1_MUCL39482 cds-NP_116692.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005428.1:214207-215145:- gene-YFR034C_MUCL42920 rna-NM_001179999.1_MUCL42920 cds-NP_116692.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011815.1:225019-225957:- gene-YFR034C_NCIM3186 rna-NM_001179999.1_NCIM3186 cds-NP_116692.1_NCIM3186 98.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005268.1:215473-216411:- gene-YFR034C_NCYC1407 rna-NM_001179999.1_NCYC1407 cds-NP_116692.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994145.1:257472-258410:- gene-YFR034C_PE2H3 rna-NM_001179999.1_PE2H3 cds-NP_116692.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999877.1:257020-257958:- gene-YFR034C_PE2H4 rna-NM_001179999.1_PE2H4 cds-NP_116692.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001138.5:225020-225958:- gene-YFR034C_S288C rna-NM_001179999.1_S288C cds-NP_116692.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000011.1:98517-99455:+ gene-YFR034C_SA1 rna-NM_001179999.1_SA1 cds-NP_116692.1_SA1 99.2 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005492.1:215095-216033:- gene-YFR034C_ThermosaccDry rna-NM_001179999.1_ThermosaccDry cds-NP_116692.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005460.1:230844-231782:- gene-YFR034C_VR1 rna-NM_001179999.1_VR1 cds-NP_116692.1_VR1 99.1 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000013.1:145563-146501:- gene-YFR034C_ZTW1 rna-NM_001179999.1_ZTW1 cds-NP_116692.1_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047492.1:238739-239683:- gene-YFR034C_Sparadoxus rna-NM_001179999.1_Sparadoxus cds-NP_116692.1_Sparadoxus 87.5 99.0 Verified 1 1 1 False True False False False

Additional files