PHO23 (YNL097C)


Gene profile

Gene name: PHO23
Reference locus (S288C): YNL097C
Gene biotype: protein_coding

Description: Transcriptional regulatory protein PHO23; Component of the Rpd3L histone deacetylase complex; involved in transcriptional regulation of PHO5; affects termination of snoRNAs and cryptic unstable transcripts (CUTs); C-terminus shares significant sequence identity with the human candidate tumor suppressor p33-ING1 and its isoform ING3

Top 10 interactors (score): RPD3 (0.999); SIN3 (0.999); CTI6 (0.999); RXT2 (0.999); HOS2 (0.998); SDS3 (0.998); SAP30 (0.998); EAF3 (0.995); UME1 (0.994); RCO1 (0.994); RXT3 (0.985); UME6 (0.98); DEP1 (0.98); ASH1 (0.977); HAT2 (0.972); SET3 (0.97); SIF2 (0.957); HHT1 (0.929); TOD6 (0.929); YNG2 (0.928)

Homologues (species, bitscore): ING3 (Homo sapiens, 97.4); Ing1 (Mus musculus, 102.1); ing3 (Danio rerio, 99.8); ing1 (Xenopus tropicalis, 100.1); CG9293 (Drosophila melanogaster, 97.4); ing-3 (Caenorhabditis elegans, 77.0); ING1 (Arabidopsis thaliana, 92.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:435015-436007:- gene-YNL097C_AKU4011 rna-NM_001182935.3_AKU4011 cds-NP_014302.3_AKU4011 99.2 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:339009-340001:- gene-YNL097C_BG1 rna-NM_001182935.3_BG1 cds-NP_014302.3_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:445732-446724:- gene-YNL097C_Bruggeman rna-NM_001182935.3_Bruggeman cds-NP_014302.3_Bruggeman 99.2 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:488763-489755:- gene-YNL097C_CAT1 rna-NM_001182935.3_CAT1 cds-NP_014302.3_CAT1 99.3 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:435616-436608:- gene-YNL097C_CBS1585 rna-NM_001182935.3_CBS1585 cds-NP_014302.3_CBS1585 99.1 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:504051-505043:- gene-YNL097C_CBS436 rna-NM_001182935.3_CBS436 cds-NP_014302.3_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:430781-431773:- gene-YNL097C_CBS6412 rna-NM_001182935.3_CBS6412 cds-NP_014302.3_CBS6412 99.2 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:432097-433089:- gene-YNL097C_CBS6413 rna-NM_001182935.3_CBS6413 cds-NP_014302.3_CBS6413 98.9 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:435196-436188:- gene-YNL097C_CENPK1137D rna-NM_001182935.3_CENPK1137D cds-NP_014302.3_CENPK1137D 99.1 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:431978-432970:- gene-YNL097C_EthanolRed rna-NM_001182935.3_EthanolRed cds-NP_014302.3_EthanolRed 99.1 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:427876-428868:- gene-YNL097C_FaliES1 rna-NM_001182935.3_FaliES1 cds-NP_014302.3_FaliES1 99.1 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000140.1:15532-16524:- gene-YNL097C_JAY291 rna-NM_001182935.3_JAY291 cds-NP_014302.3_JAY291 99.3 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:441906-442898:- gene-YNL097C_MUCL30387 rna-NM_001182935.3_MUCL30387 cds-NP_014302.3_MUCL30387 99.4 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:477282-478274:- gene-YNL097C_MUCL30388 rna-NM_001182935.3_MUCL30388 cds-NP_014302.3_MUCL30388 99.4 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:433020-434012:- gene-YNL097C_MUCL39482 rna-NM_001182935.3_MUCL39482 cds-NP_014302.3_MUCL39482 99.1 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:437028-438020:- gene-YNL097C_MUCL42920 rna-NM_001182935.3_MUCL42920 cds-NP_014302.3_MUCL42920 99.5 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:441335-442327:- gene-YNL097C_NCIM3186 rna-NM_001182935.3_NCIM3186 cds-NP_014302.3_NCIM3186 98.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:435137-436129:- gene-YNL097C_NCYC1407 rna-NM_001182935.3_NCYC1407 cds-NP_014302.3_NCYC1407 98.9 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:434043-435035:- gene-YNL097C_PE2H3 rna-NM_001182935.3_PE2H3 cds-NP_014302.3_PE2H3 99.3 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:433447-434439:- gene-YNL097C_PE2H4 rna-NM_001182935.3_PE2H4 cds-NP_014302.3_PE2H4 99.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:441366-442358:- gene-YNL097C_S288C rna-NM_001182935.3_S288C cds-NP_014302.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000024.1:26312-27304:- gene-YNL097C_SA1 rna-NM_001182935.3_SA1 cds-NP_014302.3_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:428751-429743:- gene-YNL097C_ThermosaccDry rna-NM_001182935.3_ThermosaccDry cds-NP_014302.3_ThermosaccDry 99.1 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:447488-448480:- gene-YNL097C_VR1 rna-NM_001182935.3_VR1 cds-NP_014302.3_VR1 99.2 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:338594-339586:- gene-YNL097C_ZTW1 rna-NM_001182935.3_ZTW1 cds-NP_014302.3_ZTW1 99.0 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:439642-440634:- gene-YNL097C_Sparadoxus rna-NM_001182935.3_Sparadoxus cds-NP_014302.3_Sparadoxus 91.3 100.0 Verified 1 1 1 False True False False False

Additional files