PHO2 (YDL106C)


Gene profile

Gene name: PHO2
Reference locus (S288C): YDL106C
Gene biotype: protein_coding

Description: Regulatory protein PHO2; Homeobox transcription factor; regulatory targets include genes involved in phosphate metabolism; binds cooperatively with Pho4p to the PHO5 promoter; phosphorylation of Pho2p facilitates interaction with Pho4p; relocalizes to the cytosol in response to hypoxia

Top 10 interactors (score): BAS1 (0.995); PHO4 (0.995); SWI5 (0.853); ADE13 (0.819); PHO80 (0.812); HIS1 (0.808); ADE2 (0.787); ADE5,7 (0.786); HIS4 (0.78); GCN4 (0.767); PHO85 (0.711); ADE4 (0.691); PHO81 (0.67); ADE17 (0.66); FUR1 (0.642); URK1 (0.642); DAS2 (0.642); ADE16 (0.589); SAS2 (0.57); SAS3 (0.57)

Homologues (species, bitscore): DMBX1 (Homo sapiens, 56.6); Dmbx1 (Mus musculus, 56.6); dmbx1a (Danio rerio, 61.6); dmbx1 (Xenopus tropicalis, 61.6); hbn (Drosophila melanogaster, 64.3); ceh-54 (Caenorhabditis elegans, 54.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:254849-256525:- gene-YDL106C_AKU4011 rna-NM_001180165.1_AKU4011 cds-NP_010177.1_AKU4011 99.4 99.8 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000102.1:293426-295102:+ gene-YDL106C_BG1 rna-NM_001180165.1_BG1 cds-NP_010177.1_BG1 99.5 99.8 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:272259-273935:- gene-YDL106C_Bruggeman rna-NM_001180165.1_Bruggeman cds-NP_010177.1_Bruggeman 99.5 99.8 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:269000-270676:- gene-YDL106C_CAT1 rna-NM_001180165.1_CAT1 cds-NP_010177.1_CAT1 99.0 99.8 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:253109-254785:- gene-YDL106C_CBS1585 rna-NM_001180165.1_CBS1585 cds-NP_010177.1_CBS1585 99.4 99.8 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:269769-271445:- gene-YDL106C_CBS436 rna-NM_001180165.1_CBS436 cds-NP_010177.1_CBS436 99.5 99.8 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:251535-253211:- gene-YDL106C_CBS6412 rna-NM_001180165.1_CBS6412 cds-NP_010177.1_CBS6412 99.4 99.8 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:271270-272946:- gene-YDL106C_CBS6413 rna-NM_001180165.1_CBS6413 cds-NP_010177.1_CBS6413 99.4 99.8 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:268994-270670:- gene-YDL106C_CENPK1137D rna-NM_001180165.1_CENPK1137D cds-NP_010177.1_CENPK1137D 99.2 99.8 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:265875-267551:- gene-YDL106C_EthanolRed rna-NM_001180165.1_EthanolRed cds-NP_010177.1_EthanolRed 99.4 99.8 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:271845-273521:- gene-YDL106C_FaliES1 rna-NM_001180165.1_FaliES1 cds-NP_010177.1_FaliES1 99.4 99.8 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000010.1:41889-43565:- gene-YDL106C_JAY291 rna-NM_001180165.1_JAY291 cds-NP_010177.1_JAY291 99.1 99.8 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:270045-271721:- gene-YDL106C_MUCL30387 rna-NM_001180165.1_MUCL30387 cds-NP_010177.1_MUCL30387 99.5 99.8 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:260804-262480:- gene-YDL106C_MUCL30388 rna-NM_001180165.1_MUCL30388 cds-NP_010177.1_MUCL30388 99.3 99.8 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:254215-255891:- gene-YDL106C_MUCL39482 rna-NM_001180165.1_MUCL39482 cds-NP_010177.1_MUCL39482 99.4 99.8 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:175999-177648:- gene-YDL106C_MUCL42920 rna-NM_001180165.1_MUCL42920 cds-NP_010177.1_MUCL42920 97.7 98.2 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:270145-271824:- gene-YDL106C_NCIM3186 rna-NM_001180165.1_NCIM3186 cds-NP_010177.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:254243-255919:- gene-YDL106C_NCYC1407 rna-NM_001180165.1_NCYC1407 cds-NP_010177.1_NCYC1407 99.4 99.8 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:261000-262676:- gene-YDL106C_PE2H3 rna-NM_001180165.1_PE2H3 cds-NP_010177.1_PE2H3 99.1 99.8 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:261004-262680:- gene-YDL106C_PE2H4 rna-NM_001180165.1_PE2H4 cds-NP_010177.1_PE2H4 99.1 99.8 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:270222-271901:- gene-YDL106C_S288C rna-NM_001180165.1_S288C cds-NP_010177.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000010.1:163016-164692:+ gene-YDL106C_SA1 rna-NM_001180165.1_SA1 cds-NP_010177.1_SA1 99.1 99.8 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:271356-273032:- gene-YDL106C_ThermosaccDry rna-NM_001180165.1_ThermosaccDry cds-NP_010177.1_ThermosaccDry 99.4 99.8 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:273462-275138:- gene-YDL106C_VR1 rna-NM_001180165.1_VR1 cds-NP_010177.1_VR1 99.1 99.8 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:269279-270955:- gene-YDL106C_ZTW1 rna-NM_001180165.1_ZTW1 cds-NP_010177.1_ZTW1 99.4 99.8 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:271429-273087:- gene-YDL106C_Sparadoxus rna-NM_001180165.1_Sparadoxus cds-NP_010177.1_Sparadoxus 90.3 98.7 Verified 1 1 1 False True False False False

Additional files