Gene name: PHO13
Reference locus (S288C): YDL236W
Gene biotype: protein_coding
Description: 4-nitrophenylphosphatase; Conserved phosphatase acting as a metabolite repair enzyme; shows specific dephosphorylating activity on two side-products of central carbohydrate metabolism, 2-phosphoglycolate and 4-phosphoerythronate; alkaline phosphatase specific for p-nitrophenyl phosphate; also has protein phosphatase activity; human ortholog PGP shows similar substrate specificity, deletion causes similar metabolite accumulation phenotypes, suggesting conserved role in eliminating glycolytic byproducts
Top 10 interactors (score): XKS1 (0.94); TAL1 (0.939); XYL2 (0.929); GRE3 (0.9); PHO8 (0.893); NAT4 (0.869); RPE1 (0.832); TKL1 (0.741); RKI1 (0.725); ALD6 (0.717); CYB2 (0.715); SER2 (0.713); YBR298C-A (0.698); HXT7 (0.674); ILV5 (0.653); CMC2 (0.651); PRI2 (0.644); SET1 (0.633); HST2 (0.619); FAU1 (0.599)
Homologues (species, bitscore): PGP (Homo sapiens, 171.8); Pgp (Mus musculus, 162.9); pgp (Danio rerio, 201.8); pgp (Xenopus tropicalis, 190.7); CG5567 (Drosophila melanogaster, 169.1); C53A3.2 (Caenorhabditis elegans, 149.4); PGLP1 (Arabidopsis thaliana, 201.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:15459-16397:+ | gene-YDL236W_AKU4011 | rna-NM_001180296.1_AKU4011 | cds-NP_010045.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000077.1:50114-51052:- | gene-YDL236W_BG1 | rna-NM_001180296.1_BG1 | cds-NP_010045.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:31119-32057:+ | gene-YDL236W_Bruggeman | rna-NM_001180296.1_Bruggeman | cds-NP_010045.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:34042-34980:+ | gene-YDL236W_CAT1 | rna-NM_001180296.1_CAT1 | cds-NP_010045.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:14834-15772:+ | gene-YDL236W_CBS1585 | rna-NM_001180296.1_CBS1585 | cds-NP_010045.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:31543-32481:+ | gene-YDL236W_CBS436 | rna-NM_001180296.1_CBS436 | cds-NP_010045.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:15280-16218:+ | gene-YDL236W_CBS6412 | rna-NM_001180296.1_CBS6412 | cds-NP_010045.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:32219-33157:+ | gene-YDL236W_CBS6413 | rna-NM_001180296.1_CBS6413 | cds-NP_010045.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:31264-32202:+ | gene-YDL236W_CENPK1137D | rna-NM_001180296.1_CENPK1137D | cds-NP_010045.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:28995-29933:+ | gene-YDL236W_EthanolRed | rna-NM_001180296.1_EthanolRed | cds-NP_010045.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:32297-33235:+ | gene-YDL236W_FaliES1 | rna-NM_001180296.1_FaliES1 | cds-NP_010045.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000011.1:11290-12228:- | gene-YDL236W_JAY291 | rna-NM_001180296.1_JAY291 | cds-NP_010045.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:30414-31352:+ | gene-YDL236W_MUCL30387 | rna-NM_001180296.1_MUCL30387 | cds-NP_010045.1_MUCL30387 | 99.5 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:19981-20919:+ | gene-YDL236W_MUCL30388 | rna-NM_001180296.1_MUCL30388 | cds-NP_010045.1_MUCL30388 | 99.5 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:15428-16366:+ | gene-YDL236W_MUCL39482 | rna-NM_001180296.1_MUCL39482 | cds-NP_010045.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:31552-32490:+ | gene-YDL236W_MUCL42920 | rna-NM_001180296.1_MUCL42920 | cds-NP_010045.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:32219-33157:+ | gene-YDL236W_NCIM3186 | rna-NM_001180296.1_NCIM3186 | cds-NP_010045.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:15384-16322:+ | gene-YDL236W_NCYC1407 | rna-NM_001180296.1_NCYC1407 | cds-NP_010045.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:22615-23553:+ | gene-YDL236W_PE2H3 | rna-NM_001180296.1_PE2H3 | cds-NP_010045.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:22623-23561:+ | gene-YDL236W_PE2H4 | rna-NM_001180296.1_PE2H4 | cds-NP_010045.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:32296-33234:+ | gene-YDL236W_S288C | rna-NM_001180296.1_S288C | cds-NP_010045.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000107.1:11075-12013:- | gene-YDL236W_SA1 | rna-NM_001180296.1_SA1 | cds-NP_010045.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:32425-33363:+ | gene-YDL236W_ThermosaccDry | rna-NM_001180296.1_ThermosaccDry | cds-NP_010045.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:32349-33287:+ | gene-YDL236W_VR1 | rna-NM_001180296.1_VR1 | cds-NP_010045.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:31484-32422:+ | gene-YDL236W_ZTW1 | rna-NM_001180296.1_ZTW1 | cds-NP_010045.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:34777-35716:+ | gene-YDL236W_Sparadoxus | rna-NM_001180296.1_Sparadoxus | cds-NP_010045.1_Sparadoxus | 89.5 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |