PHM8 (YER037W)


Gene profile

Gene name: PHM8
Reference locus (S288C): YER037W
Gene biotype: protein_coding

Description: Phosphate metabolism protein 8; Lysophosphatidic acid (LPA) phosphatase, nucleotidase; principle and physiological nucleotidase working on GMP, UMP and CMP; involved in LPA hydrolysis in response to phosphate starvation and ribose salvage pathway; phosphatase activity is soluble and Mg2+ dependent; expression is induced by low phosphate levels and by inactivation of Pho85p; repressed by Gcn4p under normal conditions; PHM8 has a paralog, SDT1, that arose from the whole genome duplication

Top 10 interactors (score): YJU3 (0.942); DGA1 (0.939); TGL2 (0.916); ALE1 (0.91); TGL5 (0.909); TGL3 (0.909); TGL4 (0.908); GPT2 (0.908); LOA1 (0.903); SLC1 (0.9); SCT1 (0.9); ATG15 (0.9); GUD1 (0.872); PNC1 (0.853); URH1 (0.706); PNP1 (0.687); PRM15 (0.654); ISN1 (0.653); XPT1 (0.647); RTC3 (0.647)

Homologues (species, bitscore): AT3G62040 (Arabidopsis thaliana, 93.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:219948-220913:+ gene-YER037W_AKU4011 rna-NM_001178928.1_AKU4011 cds-NP_010954.1_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000011.1:204803-205768:- gene-YER037W_BG1 rna-NM_001178928.1_BG1 cds-NP_010954.1_BG1 99.7 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:228801-229766:+ gene-YER037W_Bruggeman rna-NM_001178928.1_Bruggeman cds-NP_010954.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:222934-223899:+ gene-YER037W_CAT1 rna-NM_001178928.1_CAT1 cds-NP_010954.1_CAT1 99.7 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:219857-220822:+ gene-YER037W_CBS1585 rna-NM_001178928.1_CBS1585 cds-NP_010954.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:221802-222767:+ gene-YER037W_CBS436 rna-NM_001178928.1_CBS436 cds-NP_010954.1_CBS436 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:219740-220683:+ gene-YER037W_CBS6412 rna-NM_001178928.1_CBS6412 cds-NP_010954.1_CBS6412 79.5 91.7 Unannotated 1 1 0 False False True False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:225328-226293:+ gene-YER037W_CBS6413 rna-NM_001178928.1_CBS6413 cds-NP_010954.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:224084-225049:+ gene-YER037W_CENPK1137D rna-NM_001178928.1_CENPK1137D cds-NP_010954.1_CENPK1137D 99.6 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:220552-221517:+ gene-YER037W_EthanolRed rna-NM_001178928.1_EthanolRed cds-NP_010954.1_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:220815-221780:+ gene-YER037W_FaliES1 rna-NM_001178928.1_FaliES1 cds-NP_010954.1_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000192.1:18579-19544:+ gene-YER037W_JAY291 rna-NM_001178928.1_JAY291 cds-NP_010954.1_JAY291 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:224248-225213:+ gene-YER037W_MUCL30387 rna-NM_001178928.1_MUCL30387 cds-NP_010954.1_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:220466-221431:+ gene-YER037W_MUCL30388 rna-NM_001178928.1_MUCL30388 cds-NP_010954.1_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:218899-219864:+ gene-YER037W_MUCL39482 rna-NM_001178928.1_MUCL39482 cds-NP_010954.1_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:225975-226940:+ gene-YER037W_MUCL42920 rna-NM_001178928.1_MUCL42920 cds-NP_010954.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:225888-226853:+ gene-YER037W_NCIM3186 rna-NM_001178928.1_NCIM3186 cds-NP_010954.1_NCIM3186 98.8 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:223961-224926:+ gene-YER037W_NCYC1407 rna-NM_001178928.1_NCYC1407 cds-NP_010954.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:234590-235555:+ gene-YER037W_PE2H3 rna-NM_001178928.1_PE2H3 cds-NP_010954.1_PE2H3 99.7 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:224531-225496:+ gene-YER037W_PE2H4 rna-NM_001178928.1_PE2H4 cds-NP_010954.1_PE2H4 99.7 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:225889-226854:+ gene-YER037W_S288C rna-NM_001178928.1_S288C cds-NP_010954.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000020.1:16832-17797:- gene-YER037W_SA1 rna-NM_001178928.1_SA1 cds-NP_010954.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:221587-222552:+ gene-YER037W_ThermosaccDry rna-NM_001178928.1_ThermosaccDry cds-NP_010954.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:220686-221651:+ gene-YER037W_VR1 rna-NM_001178928.1_VR1 cds-NP_010954.1_VR1 99.7 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:218800-219765:+ gene-YER037W_ZTW1 rna-NM_001178928.1_ZTW1 cds-NP_010954.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:222625-223590:+ gene-YER037W_Sparadoxus rna-NM_001178928.1_Sparadoxus cds-NP_010954.1_Sparadoxus 91.4 100.0 Verified 1 1 1 False True False False False

Additional files