PHD1 (YKL043W)


Gene profile

Gene name: PHD1
Reference locus (S288C): YKL043W
Gene biotype: protein_coding

Description: Putative transcription factor PHD1; Transcriptional activator that enhances pseudohyphal growth; physically interacts with the Tup1-Cyc8 complex and recruits Tup1p to its targets; regulates expression of FLO11, an adhesin required for pseudohyphal filament formation; similar to StuA, an A. nidulans developmental regulator; potential Cdc28p substrate; PHD1 has a paralog, SOK2, that arose from the whole genome duplication

Top 10 interactors (score): STE12 (0.928); TEC1 (0.917); YAP6 (0.865); MMO1 (0.846); TUP1 (0.828); FLO11 (0.813); NRG1 (0.796); EFG1 (0.757); MSN1 (0.749); MSS11 (0.74); RGM1 (0.735); CIN5 (0.711); SKN7 (0.711); SFL1 (0.697); NRG2 (0.696); HMS2 (0.695); MGA1 (0.687); ROX1 (0.681); RIM101 (0.671); UME6 (0.654)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:342758-343858:+ gene-YKL043W_AKU4011 rna-NM_001179609.1_AKU4011 cds-NP_012881.1_AKU4011 99.6 100.0 Unannotated 1 1 0 False False False False True
BG1 GCA_001932575.1 Bioethanol South America MSHP01000113.1:300163-301263:- gene-YKL043W_BG1 rna-NM_001179609.1_BG1 cds-NP_012881.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:362022-363122:+ gene-YKL043W_Bruggeman rna-NM_001179609.1_Bruggeman cds-NP_012881.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:358208-359308:+ gene-YKL043W_CAT1 rna-NM_001179609.1_CAT1 cds-NP_012881.1_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:355489-356589:+ gene-YKL043W_CBS1585 rna-NM_001179609.1_CBS1585 cds-NP_012881.1_CBS1585 99.7 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:353607-354707:+ gene-YKL043W_CBS436 rna-NM_001179609.1_CBS436 cds-NP_012881.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:339622-340722:+ gene-YKL043W_CBS6412 rna-NM_001179609.1_CBS6412 cds-NP_012881.1_CBS6412 99.6 100.0 Unannotated 1 1 0 False False False False True
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:355450-356550:+ gene-YKL043W_CBS6413 rna-NM_001179609.1_CBS6413 cds-NP_012881.1_CBS6413 99.6 100.0 Unannotated 1 1 0 False False False False True
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:356406-357506:+ gene-YKL043W_CENPK1137D rna-NM_001179609.1_CENPK1137D cds-NP_012881.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:353443-354543:+ gene-YKL043W_EthanolRed rna-NM_001179609.1_EthanolRed cds-NP_012881.1_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:354259-355359:+ gene-YKL043W_FaliES1 rna-NM_001179609.1_FaliES1 cds-NP_012881.1_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000080.1:59171-60271:+ gene-YKL043W_JAY291 rna-NM_001179609.1_JAY291 cds-NP_012881.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:362923-364023:+ gene-YKL043W_MUCL30387 rna-NM_001179609.1_MUCL30387 cds-NP_012881.1_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:357813-358913:+ gene-YKL043W_MUCL30388 rna-NM_001179609.1_MUCL30388 cds-NP_012881.1_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:354785-355885:+ gene-YKL043W_MUCL39482 rna-NM_001179609.1_MUCL39482 cds-NP_012881.1_MUCL39482 99.7 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:359641-360741:+ gene-YKL043W_MUCL42920 rna-NM_001179609.1_MUCL42920 cds-NP_012881.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:356737-357837:+ gene-YKL043W_NCIM3186 rna-NM_001179609.1_NCIM3186 cds-NP_012881.1_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:354980-356080:+ gene-YKL043W_NCYC1407 rna-NM_001179609.1_NCYC1407 cds-NP_012881.1_NCYC1407 99.6 100.0 Unannotated 1 1 0 False False False False True
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:379515-380615:+ gene-YKL043W_PE2H3 rna-NM_001179609.1_PE2H3 cds-NP_012881.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:364250-365350:+ gene-YKL043W_PE2H4 rna-NM_001179609.1_PE2H4 cds-NP_012881.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:356748-357848:+ gene-YKL043W_S288C rna-NM_001179609.1_S288C cds-NP_012881.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000027.1:34856-35956:+ gene-YKL043W_SA1 rna-NM_001179609.1_SA1 cds-NP_012881.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:355449-356549:+ gene-YKL043W_ThermosaccDry rna-NM_001179609.1_ThermosaccDry cds-NP_012881.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:354586-355686:+ gene-YKL043W_VR1 rna-NM_001179609.1_VR1 cds-NP_012881.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:353461-354561:+ gene-YKL043W_ZTW1 rna-NM_001179609.1_ZTW1 cds-NP_012881.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:372730-373830:+ gene-YKL043W_Sparadoxus rna-NM_001179609.1_Sparadoxus cds-NP_012881.1_Sparadoxus 90.1 100.0 Verified 1 1 1 False True False False False

Additional files