Gene name: PHB2
Reference locus (S288C): YGR231C
Gene biotype: protein_coding
Description: Prohibitin-2; Subunit of the prohibitin complex (Phb1p-Phb2p); prohibitin is a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation; prohibitin deficiency induces a mitochondrial unfolded protein response (mtUPR)
Top 10 interactors (score): PHB1 (0.999); RIP1 (0.989); AFG3 (0.985); COR1 (0.982); MAS1 (0.981); POR1 (0.977); YTA12 (0.967); POR2 (0.966); SSC1 (0.938); TOM40 (0.934); YME1 (0.932); TUF1 (0.924); CCT5 (0.912); CYT1 (0.903); RML2 (0.892); PRT1 (0.891); PAM16 (0.867); VAS1 (0.858); OMA1 (0.84); PUF6 (0.839)
Homologues (species, bitscore): PHB2 (Homo sapiens, 305.8); Phb2 (Mus musculus, 305.8); phb2 (Danio rerio, 317.4); phb2 (Xenopus tropicalis, 297.0); Phb2 (Drosophila melanogaster, 316.2); phb-2 (Caenorhabditis elegans, 303.5); PHB2 (Arabidopsis thaliana, 313.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:917947-918879:- | gene-YGR231C_AKU4011 | rna-NM_001181360.1_AKU4011 | cds-NP_011747.2_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:198064-198996:- | gene-YGR231C_BG1 | rna-NM_001181360.1_BG1 | cds-NP_011747.2_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:925545-926477:- | gene-YGR231C_Bruggeman | rna-NM_001181360.1_Bruggeman | cds-NP_011747.2_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:924243-925175:- | gene-YGR231C_CAT1 | rna-NM_001181360.1_CAT1 | cds-NP_011747.2_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:920811-921743:- | gene-YGR231C_CBS1585 | rna-NM_001181360.1_CBS1585 | cds-NP_011747.2_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:924471-925403:- | gene-YGR231C_CBS436 | rna-NM_001181360.1_CBS436 | cds-NP_011747.2_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:911681-912613:- | gene-YGR231C_CBS6412 | rna-NM_001181360.1_CBS6412 | cds-NP_011747.2_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:917740-918672:- | gene-YGR231C_CBS6413 | rna-NM_001181360.1_CBS6413 | cds-NP_011747.2_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:952195-953127:- | gene-YGR231C_CENPK1137D | rna-NM_001181360.1_CENPK1137D | cds-NP_011747.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:905950-906882:- | gene-YGR231C_EthanolRed | rna-NM_001181360.1_EthanolRed | cds-NP_011747.2_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:910585-911517:- | gene-YGR231C_FaliES1 | rna-NM_001181360.1_FaliES1 | cds-NP_011747.2_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000076.1:118757-119689:+ | gene-YGR231C_JAY291 | rna-NM_001181360.1_JAY291 | cds-NP_011747.2_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:923460-924392:- | gene-YGR231C_MUCL30387 | rna-NM_001181360.1_MUCL30387 | cds-NP_011747.2_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:922714-923646:- | gene-YGR231C_MUCL30388 | rna-NM_001181360.1_MUCL30388 | cds-NP_011747.2_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:915886-916818:- | gene-YGR231C_MUCL39482 | rna-NM_001181360.1_MUCL39482 | cds-NP_011747.2_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:934438-935370:- | gene-YGR231C_MUCL42920 | rna-NM_001181360.1_MUCL42920 | cds-NP_011747.2_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:952548-953480:- | gene-YGR231C_NCIM3186 | rna-NM_001181360.1_NCIM3186 | cds-NP_011747.2_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:911543-912475:- | gene-YGR231C_NCYC1407 | rna-NM_001181360.1_NCYC1407 | cds-NP_011747.2_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:936742-937674:- | gene-YGR231C_PE2H3 | rna-NM_001181360.1_PE2H3 | cds-NP_011747.2_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:941581-942513:- | gene-YGR231C_PE2H4 | rna-NM_001181360.1_PE2H4 | cds-NP_011747.2_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:952548-953480:- | gene-YGR231C_S288C | rna-NM_001181360.1_S288C | cds-NP_011747.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000045.1:48012-48944:+ | gene-YGR231C_SA1 | rna-NM_001181360.1_SA1 | cds-NP_011747.2_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:931096-932028:- | gene-YGR231C_ThermosaccDry | rna-NM_001181360.1_ThermosaccDry | cds-NP_011747.2_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:1035888-1036820:- | gene-YGR231C_VR1 | rna-NM_001181360.1_VR1 | cds-NP_011747.2_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:232528-233460:- | gene-YGR231C_ZTW1 | rna-NM_001181360.1_ZTW1 | cds-NP_011747.2_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:923295-924227:- | gene-YGR231C_Sparadoxus | rna-NM_001181360.1_Sparadoxus | cds-NP_011747.2_Sparadoxus | 91.3 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |