PGK1 (YCR012W)


Gene profile

Gene name: PGK1
Reference locus (S288C): YCR012W
Gene biotype: protein_coding

Description: 3-phosphoglycerate kinase; catalyzes transfer of high-energy phosphoryl groups from the acyl phosphate of 1,3-bisphosphoglycerate to ADP to produce ATP; key enzyme in glycolysis and gluconeogenesis

Top 10 interactors (score): GPM1 (0.999); TPI1 (0.999); TDH1 (0.999); TDH2 (0.999); ENO1 (0.999); TDH3 (0.999); PGI1 (0.999); FBA1 (0.998); ENO2 (0.998); CDC19 (0.998); ADH1 (0.993); TEF1 (0.989); YOR283W (0.989); GPM2 (0.987); GND1 (0.983); ACT1 (0.98); GND2 (0.979); SEC4 (0.978); GPM3 (0.973); PYK2 (0.97)

Homologues (species, bitscore): PGK1 (Homo sapiens, 545.0); Pgk1 (Mus musculus, 537.7); pgk1 (Danio rerio, 530.8); pgk1 (Xenopus tropicalis, 528.1); Pgk (Drosophila melanogaster, 513.1); pgk-1 (Caenorhabditis elegans, 560.8); PGK1 (Arabidopsis thaliana, 383.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005297.1:132120-133370:+ gene-YCR012W_AKU4011 rna-NM_001178725.1_AKU4011 cds-NP_009938.2_AKU4011 99.9 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000178.1:12636-13886:- gene-YCR012W_BG1 rna-NM_001178725.1_BG1 cds-NP_009938.2_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005505.1:127932-129182:+ gene-YCR012W_Bruggeman rna-NM_001178725.1_Bruggeman cds-NP_009938.2_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005521.1:138334-139584:+ gene-YCR012W_CAT1 rna-NM_001178725.1_CAT1 cds-NP_009938.2_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005361.1:132770-134020:+ gene-YCR012W_CBS1585 rna-NM_001178725.1_CBS1585 cds-NP_009938.2_CBS1585 99.9 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005345.1:138029-139279:+ gene-YCR012W_CBS436 rna-NM_001178725.1_CBS436 cds-NP_009938.2_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005329.1:120230-121480:+ gene-YCR012W_CBS6412 rna-NM_001178725.1_CBS6412 cds-NP_009938.2_CBS6412 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005313.1:132077-133327:+ gene-YCR012W_CBS6413 rna-NM_001178725.1_CBS6413 cds-NP_009938.2_CBS6413 99.9 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001524.1:143224-144474:+ gene-YCR012W_CENPK1137D rna-NM_001178725.1_CENPK1137D cds-NP_009938.2_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005473.1:130138-131388:+ gene-YCR012W_EthanolRed rna-NM_001178725.1_EthanolRed cds-NP_009938.2_EthanolRed 99.9 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005537.1:132436-133686:+ gene-YCR012W_FaliES1 rna-NM_001178725.1_FaliES1 cds-NP_009938.2_FaliES1 99.9 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000126.1:46606-47856:+ gene-YCR012W_JAY291 rna-NM_001178725.1_JAY291 cds-NP_009938.2_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005409.1:125737-126987:+ gene-YCR012W_MUCL30387 rna-NM_001178725.1_MUCL30387 cds-NP_009938.2_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005441.1:124709-125959:+ gene-YCR012W_MUCL30388 rna-NM_001178725.1_MUCL30388 cds-NP_009938.2_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005281.1:133187-134437:+ gene-YCR012W_MUCL39482 rna-NM_001178725.1_MUCL39482 cds-NP_009938.2_MUCL39482 99.9 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005425.1:128422-129672:+ gene-YCR012W_MUCL42920 rna-NM_001178725.1_MUCL42920 cds-NP_009938.2_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011812.1:137378-138628:+ gene-YCR012W_NCIM3186 rna-NM_001178725.1_NCIM3186 cds-NP_009938.2_NCIM3186 99.7 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005265.1:133918-135168:+ gene-YCR012W_NCYC1407 rna-NM_001178725.1_NCYC1407 cds-NP_009938.2_NCYC1407 99.9 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994142.1:137865-139115:+ gene-YCR012W_PE2H3 rna-NM_001178725.1_PE2H3 cds-NP_009938.2_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999874.1:137804-139054:+ gene-YCR012W_PE2H4 rna-NM_001178725.1_PE2H4 cds-NP_009938.2_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001135.5:137746-138996:+ gene-YCR012W_S288C rna-NM_001178725.1_S288C cds-NP_009938.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000073.1:12673-13923:- gene-YCR012W_SA1 rna-NM_001178725.1_SA1 cds-NP_009938.2_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005489.1:133004-134254:+ gene-YCR012W_ThermosaccDry rna-NM_001178725.1_ThermosaccDry cds-NP_009938.2_ThermosaccDry 99.9 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005457.1:143934-145184:+ gene-YCR012W_VR1 rna-NM_001178725.1_VR1 cds-NP_009938.2_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000004.1:131940-133190:+ gene-YCR012W_ZTW1 rna-NM_001178725.1_ZTW1 cds-NP_009938.2_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047489.1:164102-165352:+ gene-YCR012W_Sparadoxus rna-NM_001178725.1_Sparadoxus cds-NP_009938.2_Sparadoxus 98.2 100.0 Verified 1 1 1 False True False False False

Additional files