Gene name: PGA3
Reference locus (S288C): YML125C
Gene biotype: protein_coding
Description: Plasma membrane-associated coenzyme Q6 reductase PGA3; Putative cytochrome b5 reductase, localized to the plasma membrane; may be involved in regulation of lifespan; required for maturation of Gas1p and Pho8p, proposed to be involved in protein trafficking; PGA3 has a paralog, AIM33, that arose from the whole genome duplication
Top 10 interactors (score): CYB5 (0.815); IRC21 (0.687); OLE1 (0.632); URA1 (0.626); FMO1 (0.618); AIF1 (0.609); CYB2 (0.607); DUS1 (0.607); EMP46 (0.568); SCS7 (0.564); ISC1 (0.551); ERG4 (0.536); CAR1 (0.503); ARH1 (0.497); AIM14 (0.495); ERO1 (0.492); COX14 (0.481); COQ6 (0.477); GCN3 (0.466); CIN1 (0.453)
Homologues (species, bitscore): CYB5R1 (Homo sapiens, 184.9); Cyb5r1 (Mus musculus, 186.0); cyb5r3 (Danio rerio, 173.3); cyb5r2 (Xenopus tropicalis, 166.8); CG5946 (Drosophila melanogaster, 149.8); T05H4.4 (Caenorhabditis elegans, 174.1); AT5G20080 (Arabidopsis thaliana, 199.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:14473-15411:- | gene-YML125C_AKU4011 | rna-NM_001182488.1_AKU4011 | cds-NP_013581.1_AKU4011 | 94.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:461736-462674:+ | gene-YML125C_BG1 | rna-NM_001182488.1_BG1 | cds-NP_013581.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:20714-21652:- | gene-YML125C_Bruggeman | rna-NM_001182488.1_Bruggeman | cds-NP_013581.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:22294-23232:- | gene-YML125C_CAT1 | rna-NM_001182488.1_CAT1 | cds-NP_013581.1_CAT1 | 94.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:14473-15411:- | gene-YML125C_CBS1585 | rna-NM_001182488.1_CBS1585 | cds-NP_013581.1_CBS1585 | 94.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:20474-21412:- | gene-YML125C_CBS436 | rna-NM_001182488.1_CBS436 | cds-NP_013581.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:15235-16173:- | gene-YML125C_CBS6412 | rna-NM_001182488.1_CBS6412 | cds-NP_013581.1_CBS6412 | 94.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:13699-14637:- | gene-YML125C_CBS6413 | rna-NM_001182488.1_CBS6413 | cds-NP_013581.1_CBS6413 | 94.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:15280-16218:- | gene-YML125C_CENPK1137D | rna-NM_001182488.1_CENPK1137D | cds-NP_013581.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:14986-15924:- | gene-YML125C_EthanolRed | rna-NM_001182488.1_EthanolRed | cds-NP_013581.1_EthanolRed | 94.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:15261-16199:- | gene-YML125C_FaliES1 | rna-NM_001182488.1_FaliES1 | cds-NP_013581.1_FaliES1 | 94.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000345.1:74040-74978:+ | gene-YML125C_JAY291 | rna-NM_001182488.1_JAY291 | cds-NP_013581.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:18759-19697:- | gene-YML125C_MUCL30387 | rna-NM_001182488.1_MUCL30387 | cds-NP_013581.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:22177-23115:- | gene-YML125C_MUCL30388 | rna-NM_001182488.1_MUCL30388 | cds-NP_013581.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:14527-15465:- | gene-YML125C_MUCL39482 | rna-NM_001182488.1_MUCL39482 | cds-NP_013581.1_MUCL39482 | 94.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:18189-19134:- | gene-YML125C_MUCL42920 | rna-NM_001182488.1_MUCL42920 | cds-NP_013581.1_MUCL42920 | 92.8 | 97.4 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:20715-21653:- | gene-YML125C_NCIM3186 | rna-NM_001182488.1_NCIM3186 | cds-NP_013581.1_NCIM3186 | 97.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:15282-16220:- | gene-YML125C_NCYC1407 | rna-NM_001182488.1_NCYC1407 | cds-NP_013581.1_NCYC1407 | 94.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:20662-21600:- | gene-YML125C_PE2H3 | rna-NM_001182488.1_PE2H3 | cds-NP_013581.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:20600-21538:- | gene-YML125C_PE2H4 | rna-NM_001182488.1_PE2H4 | cds-NP_013581.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:20761-21699:- | gene-YML125C_S288C | rna-NM_001182488.1_S288C | cds-NP_013581.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000054.1:12589-13527:- | gene-YML125C_SA1 | rna-NM_001182488.1_SA1 | cds-NP_013581.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:14561-15499:- | gene-YML125C_ThermosaccDry | rna-NM_001182488.1_ThermosaccDry | cds-NP_013581.1_ThermosaccDry | 94.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:18965-19903:- | gene-YML125C_VR1 | rna-NM_001182488.1_VR1 | cds-NP_013581.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000026.1:13751-14689:- | gene-YML125C_ZTW1 | rna-NM_001182488.1_ZTW1 | cds-NP_013581.1_ZTW1 | 94.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:25658-26596:- | gene-YML125C_Sparadoxus | rna-NM_001182488.1_Sparadoxus | cds-NP_013581.1_Sparadoxus | 94.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |