Gene name: PFK27
Reference locus (S288C): YOL136C
Gene biotype: protein_coding
Description: 6-phosphofructo-2-kinase; catalyzes synthesis of fructose-2,6-bisphosphate; inhibited by phosphoenolpyruvate and sn-glycerol 3-phosphate, expression induced by glucose and sucrose, transcriptional regulation involves protein kinase A
Top 10 interactors (score): PFK1 (0.99); FBP1 (0.983); PFK2 (0.947); FBP26 (0.938); GRR1 (0.936); PMI40 (0.905); YLR345W (0.9); PFK26 (0.883); HXK2 (0.765); YLR446W (0.761); HXK1 (0.749); GLK1 (0.697); EMI2 (0.679); RFC5 (0.645); ISC1 (0.641); TPK3 (0.581); TPK1 (0.537); TPK2 (0.537); TYE7 (0.497); VPS62 (0.489)
Homologues (species, bitscore): PFKFB1 (Homo sapiens, 68.9); Pfkfb1 (Mus musculus, 67.8); pfkfb2a (Danio rerio, 71.6); pfkfb1 (Xenopus tropicalis, 75.1); Pfrx (Drosophila melanogaster, 72.8); K02B2.1 (Caenorhabditis elegans, 78.2); F2KP (Arabidopsis thaliana, 58.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:56219-57412:- | gene-YOL136C_AKU4011 | rna-NM_001183390.1_AKU4011 | cds-NP_014505.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000172.1:21840-23033:- | gene-YOL136C_BG1 | rna-NM_001183390.1_BG1 | cds-NP_014505.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:57496-58689:- | gene-YOL136C_Bruggeman | rna-NM_001183390.1_Bruggeman | cds-NP_014505.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:56454-57647:- | gene-YOL136C_CAT1 | rna-NM_001183390.1_CAT1 | cds-NP_014505.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:50693-51886:- | gene-YOL136C_CBS1585 | rna-NM_001183390.1_CBS1585 | cds-NP_014505.1_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:56542-57735:- | gene-YOL136C_CBS436 | rna-NM_001183390.1_CBS436 | cds-NP_014505.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:50559-51752:- | gene-YOL136C_CBS6412 | rna-NM_001183390.1_CBS6412 | cds-NP_014505.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:57027-58220:- | gene-YOL136C_CBS6413 | rna-NM_001183390.1_CBS6413 | cds-NP_014505.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:67457-68650:- | gene-YOL136C_CENPK1137D | rna-NM_001183390.1_CENPK1137D | cds-NP_014505.1_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:54470-55663:- | gene-YOL136C_EthanolRed | rna-NM_001183390.1_EthanolRed | cds-NP_014505.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:56499-57692:- | gene-YOL136C_FaliES1 | rna-NM_001183390.1_FaliES1 | cds-NP_014505.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000329.1:24862-26055:+ | gene-YOL136C_JAY291 | rna-NM_001183390.1_JAY291 | cds-NP_014505.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:62136-63329:- | gene-YOL136C_MUCL30387 | rna-NM_001183390.1_MUCL30387 | cds-NP_014505.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:65130-66323:- | gene-YOL136C_MUCL30388 | rna-NM_001183390.1_MUCL30388 | cds-NP_014505.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:58628-59821:- | gene-YOL136C_MUCL39482 | rna-NM_001183390.1_MUCL39482 | cds-NP_014505.1_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:74516-75709:- | gene-YOL136C_MUCL42920 | rna-NM_001183390.1_MUCL42920 | cds-NP_014505.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:67450-68643:- | gene-YOL136C_NCIM3186 | rna-NM_001183390.1_NCIM3186 | cds-NP_014505.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:64669-65862:- | gene-YOL136C_NCYC1407 | rna-NM_001183390.1_NCYC1407 | cds-NP_014505.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:43095-44288:- | gene-YOL136C_PE2H3 | rna-NM_001183390.1_PE2H3 | cds-NP_014505.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:60043-61236:- | gene-YOL136C_PE2H4 | rna-NM_001183390.1_PE2H4 | cds-NP_014505.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:67561-68754:- | gene-YOL136C_S288C | rna-NM_001183390.1_S288C | cds-NP_014505.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:40992-42185:- | gene-YOL136C_SA1 | rna-NM_001183390.1_SA1 | cds-NP_014505.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:55637-56830:- | gene-YOL136C_ThermosaccDry | rna-NM_001183390.1_ThermosaccDry | cds-NP_014505.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:56293-57486:- | gene-YOL136C_VR1 | rna-NM_001183390.1_VR1 | cds-NP_014505.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000031.1:55391-56585:- | gene-YOL136C_ZTW1 | rna-NM_001183390.1_ZTW1 | cds-NP_014505.1_ZTW1 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:57851-59044:- | gene-YOL136C_Sparadoxus | rna-NM_001183390.1_Sparadoxus | cds-NP_014505.1_Sparadoxus | 91.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |