Gene name: PFK2
Reference locus (S288C): YMR205C
Gene biotype: protein_coding
Description: Beta subunit of heterooctameric phosphofructokinase; involved in glycolysis; indispensable for anaerobic growth; activated by fructose-2,6-bisphosphate and AMP; mutation inhibits glucose induction of cell cycle-related genes; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily
Top 10 interactors (score): PFK1 (0.999); PGI1 (0.998); TPI1 (0.982); FBA1 (0.974); TAL1 (0.974); CDC19 (0.966); SEC4 (0.963); TKL1 (0.962); PYK2 (0.961); YLR345W (0.959); GPH1 (0.959); PFK26 (0.949); FBP26 (0.949); NQM1 (0.948); PFK27 (0.947); FBP1 (0.947); TKL2 (0.933); PMI40 (0.93); EMI2 (0.917); HXK1 (0.914)
Homologues (species, bitscore): PFKP (Homo sapiens, 634.4); Pfkm (Mus musculus, 627.9); pfkpa (Danio rerio, 622.5); pfkm (Xenopus tropicalis, 616.7); Pfk (Drosophila melanogaster, 609.8); Y71H10A.1 (Caenorhabditis elegans, 598.6); PFK5 (Arabidopsis thaliana, 73.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:711814-714693:- | gene-YMR205C_AKU4011 | rna-NM_001182712.1_AKU4011 | cds-NP_013932.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:239852-242731:+ | gene-YMR205C_BG1 | rna-NM_001182712.1_BG1 | cds-NP_013932.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:656028-658907:- | gene-YMR205C_Bruggeman | rna-NM_001182712.1_Bruggeman | cds-NP_013932.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:659281-662160:- | gene-YMR205C_CAT1 | rna-NM_001182712.1_CAT1 | cds-NP_013932.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:644072-646951:- | gene-YMR205C_CBS1585 | rna-NM_001182712.1_CBS1585 | cds-NP_013932.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:648321-651200:- | gene-YMR205C_CBS436 | rna-NM_001182712.1_CBS436 | cds-NP_013932.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:755629-758508:- | gene-YMR205C_CBS6412 | rna-NM_001182712.1_CBS6412 | cds-NP_013932.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:643221-646100:- | gene-YMR205C_CBS6413 | rna-NM_001182712.1_CBS6413 | cds-NP_013932.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:666573-669452:- | gene-YMR205C_CENPK1137D | rna-NM_001182712.1_CENPK1137D | cds-NP_013932.1_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:704277-707156:- | gene-YMR205C_EthanolRed | rna-NM_001182712.1_EthanolRed | cds-NP_013932.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:649931-652810:- | gene-YMR205C_FaliES1 | rna-NM_001182712.1_FaliES1 | cds-NP_013932.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000141.1:133224-136103:+ | gene-YMR205C_JAY291 | rna-NM_001182712.1_JAY291 | cds-NP_013932.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:649575-652454:- | gene-YMR205C_MUCL30387 | rna-NM_001182712.1_MUCL30387 | cds-NP_013932.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:656351-659230:- | gene-YMR205C_MUCL30388 | rna-NM_001182712.1_MUCL30388 | cds-NP_013932.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:645142-648021:- | gene-YMR205C_MUCL39482 | rna-NM_001182712.1_MUCL39482 | cds-NP_013932.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:652470-655349:- | gene-YMR205C_MUCL42920 | rna-NM_001182712.1_MUCL42920 | cds-NP_013932.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:671841-674720:- | gene-YMR205C_NCIM3186 | rna-NM_001182712.1_NCIM3186 | cds-NP_013932.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:644794-647673:- | gene-YMR205C_NCYC1407 | rna-NM_001182712.1_NCYC1407 | cds-NP_013932.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:654639-657518:- | gene-YMR205C_PE2H3 | rna-NM_001182712.1_PE2H3 | cds-NP_013932.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:655654-658533:- | gene-YMR205C_PE2H4 | rna-NM_001182712.1_PE2H4 | cds-NP_013932.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:671887-674766:- | gene-YMR205C_S288C | rna-NM_001182712.1_S288C | cds-NP_013932.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:133344-136223:+ | gene-YMR205C_SA1 | rna-NM_001182712.1_SA1 | cds-NP_013932.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:646101-648980:- | gene-YMR205C_ThermosaccDry | rna-NM_001182712.1_ThermosaccDry | cds-NP_013932.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:659172-662051:- | gene-YMR205C_VR1 | rna-NM_001182712.1_VR1 | cds-NP_013932.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000028.1:61804-64683:- | gene-YMR205C_ZTW1 | rna-NM_001182712.1_ZTW1 | cds-NP_013932.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:663881-666760:- | gene-YMR205C_Sparadoxus | rna-NM_001182712.1_Sparadoxus | cds-NP_013932.1_Sparadoxus | 94.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |