PFA5 (YDR459C)


Gene profile

Gene name: PFA5
Reference locus (S288C): YDR459C
Gene biotype: protein_coding

Description: Palmitoyltransferase with autoacylation activity; likely functions in pathway(s) outside Ras; member of a family of putative palmitoyltransferases containing an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; Belongs to the DHHC palmitoyltransferase family. PFA5 subfamily

Top 10 interactors (score): AKR2 (0.935); SWF1 (0.923); NCP1 (0.903); AKR1 (0.902); YPL199C (0.755); SHR5 (0.754); VAC8 (0.735); ANR2 (0.711); YCK2 (0.689); SNA4 (0.611); ENV7 (0.581); TRM2 (0.565); ELF1 (0.554); YCK1 (0.543); PUT1 (0.535); LCB4 (0.506); ARE2 (0.502); SAC3 (0.499); RAS2 (0.497); RRP46 (0.486)

Homologues (species, bitscore): ZDHHC15 (Homo sapiens, 76.3); Zdhhc15 (Mus musculus, 76.6); zgc:162723 (Danio rerio, 71.6); zdhhc15 (Xenopus tropicalis, 82.4); CG8314 (Drosophila melanogaster, 62.4); F33D11.12 (Caenorhabditis elegans, 58.2); AT5G05070 (Arabidopsis thaliana, 72.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:1322223-1323347:- gene-YDR459C_AKU4011 rna-NM_001180767.1_AKU4011 cds-NP_010747.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000039.1:200583-201707:- gene-YDR459C_BG1 rna-NM_001180767.1_BG1 cds-NP_010747.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1353656-1354780:- gene-YDR459C_Bruggeman rna-NM_001180767.1_Bruggeman cds-NP_010747.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1330802-1331926:- gene-YDR459C_CAT1 rna-NM_001180767.1_CAT1 cds-NP_010747.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1316529-1317653:- gene-YDR459C_CBS1585 rna-NM_001180767.1_CBS1585 cds-NP_010747.1_CBS1585 99.5 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1335904-1337028:- gene-YDR459C_CBS436 rna-NM_001180767.1_CBS436 cds-NP_010747.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1312157-1313281:- gene-YDR459C_CBS6412 rna-NM_001180767.1_CBS6412 cds-NP_010747.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1335168-1336292:- gene-YDR459C_CBS6413 rna-NM_001180767.1_CBS6413 cds-NP_010747.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1380993-1382117:- gene-YDR459C_CENPK1137D rna-NM_001180767.1_CENPK1137D cds-NP_010747.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:1325578-1326702:- gene-YDR459C_EthanolRed rna-NM_001180767.1_EthanolRed cds-NP_010747.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1329131-1330255:- gene-YDR459C_FaliES1 rna-NM_001180767.1_FaliES1 cds-NP_010747.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000026.1:27392-28516:- gene-YDR459C_JAY291 rna-NM_001180767.1_JAY291 cds-NP_010747.1_JAY291 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1336147-1337271:- gene-YDR459C_MUCL30387 rna-NM_001180767.1_MUCL30387 cds-NP_010747.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1318170-1319294:- gene-YDR459C_MUCL30388 rna-NM_001180767.1_MUCL30388 cds-NP_010747.1_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1308013-1309137:- gene-YDR459C_MUCL39482 rna-NM_001180767.1_MUCL39482 cds-NP_010747.1_MUCL39482 99.5 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:1250814-1251938:- gene-YDR459C_MUCL42920 rna-NM_001180767.1_MUCL42920 cds-NP_010747.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1382242-1383366:- gene-YDR459C_NCIM3186 rna-NM_001180767.1_NCIM3186 cds-NP_010747.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1321785-1322909:- gene-YDR459C_NCYC1407 rna-NM_001180767.1_NCYC1407 cds-NP_010747.1_NCYC1407 99.3 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1332641-1333765:- gene-YDR459C_PE2H3 rna-NM_001180767.1_PE2H3 cds-NP_010747.1_PE2H3 99.9 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1338198-1339322:- gene-YDR459C_PE2H4 rna-NM_001180767.1_PE2H4 cds-NP_010747.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1382319-1383443:- gene-YDR459C_S288C rna-NM_001180767.1_S288C cds-NP_010747.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000004.1:233721-234845:+ gene-YDR459C_SA1 rna-NM_001180767.1_SA1 cds-NP_010747.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1333353-1334477:- gene-YDR459C_ThermosaccDry rna-NM_001180767.1_ThermosaccDry cds-NP_010747.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:1349088-1350212:- gene-YDR459C_VR1 rna-NM_001180767.1_VR1 cds-NP_010747.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:376028-377152:- gene-YDR459C_ZTW1 rna-NM_001180767.1_ZTW1 cds-NP_010747.1_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1336430-1337569:- gene-YDR459C_Sparadoxus rna-NM_001180767.1_Sparadoxus cds-NP_010747.1_Sparadoxus 87.9 100.0 Verified 1 1 1 False True False False False

Additional files