PFA4 (YOL003C)


Gene profile

Gene name: PFA4
Reference locus (S288C): YOL003C
Gene biotype: protein_coding

Description: Palmitoyltransferase with autoacylation activity; required for palmitoylation of amino acid permeases containing a C-terminal Phe-Trp-Cys site; required for modification of Chs3p; member of the DHHC family of putative palmitoyltransferases

Top 10 interactors (score): AKR1 (0.962); AKR2 (0.951); NCP1 (0.901); VAC8 (0.891); CHS1 (0.865); PSO2 (0.861); CHS3 (0.858); SHR5 (0.827); CHS7 (0.768); SNA4 (0.746); ENV7 (0.726); YPL199C (0.7); YCK2 (0.659); YCK1 (0.626); CHS2 (0.614); ANR2 (0.611); VTI1 (0.607); SEC23 (0.604); SMI1 (0.596); RAS2 (0.595)

Homologues (species, bitscore): ZDHHC20 (Homo sapiens, 90.1); Zdhhc20 (Mus musculus, 89.7); zgc:162723 (Danio rerio, 85.1); zdhhc16 (Xenopus tropicalis, 90.1); CG5196 (Drosophila melanogaster, 94.7); M18.8 (Caenorhabditis elegans, 84.0); AT3G60800 (Arabidopsis thaliana, 102.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:306251-307387:- gene-YOL003C_AKU4011 rna-NM_001183257.1_AKU4011 cds-NP_014640.1_AKU4011 99.1 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000152.1:121813-122949:- gene-YOL003C_BG1 rna-NM_001183257.1_BG1 cds-NP_014640.1_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:309026-310162:- gene-YOL003C_Bruggeman rna-NM_001183257.1_Bruggeman cds-NP_014640.1_Bruggeman 99.2 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:307159-308295:- gene-YOL003C_CAT1 rna-NM_001183257.1_CAT1 cds-NP_014640.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:300927-302063:- gene-YOL003C_CBS1585 rna-NM_001183257.1_CBS1585 cds-NP_014640.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:305164-306300:- gene-YOL003C_CBS436 rna-NM_001183257.1_CBS436 cds-NP_014640.1_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:300231-301367:- gene-YOL003C_CBS6412 rna-NM_001183257.1_CBS6412 cds-NP_014640.1_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:307764-308900:- gene-YOL003C_CBS6413 rna-NM_001183257.1_CBS6413 cds-NP_014640.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:321576-322712:- gene-YOL003C_CENPK1137D rna-NM_001183257.1_CENPK1137D cds-NP_014640.1_CENPK1137D 99.2 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:303016-304152:- gene-YOL003C_EthanolRed rna-NM_001183257.1_EthanolRed cds-NP_014640.1_EthanolRed 99.0 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:306343-307479:- gene-YOL003C_FaliES1 rna-NM_001183257.1_FaliES1 cds-NP_014640.1_FaliES1 98.9 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000015.1:21787-22923:+ gene-YOL003C_JAY291 rna-NM_001183257.1_JAY291 cds-NP_014640.1_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:313241-314377:- gene-YOL003C_MUCL30387 rna-NM_001183257.1_MUCL30387 cds-NP_014640.1_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:316677-317813:- gene-YOL003C_MUCL30388 rna-NM_001183257.1_MUCL30388 cds-NP_014640.1_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:308410-309546:- gene-YOL003C_MUCL39482 rna-NM_001183257.1_MUCL39482 cds-NP_014640.1_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:323264-324400:- gene-YOL003C_MUCL42920 rna-NM_001183257.1_MUCL42920 cds-NP_014640.1_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:321747-322883:- gene-YOL003C_NCIM3186 rna-NM_001183257.1_NCIM3186 cds-NP_014640.1_NCIM3186 98.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:315096-316232:- gene-YOL003C_NCYC1407 rna-NM_001183257.1_NCYC1407 cds-NP_014640.1_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:309753-310889:- gene-YOL003C_PE2H3 rna-NM_001183257.1_PE2H3 cds-NP_014640.1_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:320132-321268:- gene-YOL003C_PE2H4 rna-NM_001183257.1_PE2H4 cds-NP_014640.1_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:321858-322994:- gene-YOL003C_S288C rna-NM_001183257.1_S288C cds-NP_014640.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000001.1:289840-290976:- gene-YOL003C_SA1 rna-NM_001183257.1_SA1 cds-NP_014640.1_SA1 99.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:304914-306050:- gene-YOL003C_ThermosaccDry rna-NM_001183257.1_ThermosaccDry cds-NP_014640.1_ThermosaccDry 99.1 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:305715-306851:- gene-YOL003C_VR1 rna-NM_001183257.1_VR1 cds-NP_014640.1_VR1 99.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:39579-40715:- gene-YOL003C_ZTW1 rna-NM_001183257.1_ZTW1 cds-NP_014640.1_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:313307-314443:- gene-YOL003C_Sparadoxus rna-NM_001183257.1_Sparadoxus cds-NP_014640.1_Sparadoxus 87.2 99.8 Verified 1 1 1 False True False False False

Additional files