Gene name: PFA3
Reference locus (S288C): YNL326C
Gene biotype: protein_coding
Description: Palmitoyltransferase for Vac8p; required for vacuolar membrane fusion; contains an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; autoacylates; required for vacuolar integrity under stress conditions; Belongs to the DHHC palmitoyltransferase family. PFA3 subfamily
Top 10 interactors (score): VAC8 (0.99); AKR1 (0.968); AKR2 (0.967); NMT1 (0.831); SHR5 (0.819); TLG1 (0.793); MEH1 (0.765); YPL199C (0.712); YCK2 (0.686); RFC2 (0.684); YIF1 (0.656); ANR2 (0.65); TPI1 (0.647); SNA4 (0.614); RAS2 (0.613); VFA1 (0.611); YNL320W (0.587); HUT1 (0.586); YLR118C (0.575); YMD8 (0.574)
Homologues (species, bitscore): ZDHHC20 (Homo sapiens, 120.9); Zdhhc20 (Mus musculus, 118.6); zdhhc20b (Danio rerio, 118.6); zdhhc20 (Xenopus tropicalis, 123.2); CG1407 (Drosophila melanogaster, 109.0); F33D11.12 (Caenorhabditis elegans, 87.0); AT3G60800 (Arabidopsis thaliana, 95.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:21139-22149:- | gene-YNL326C_AKU4011 | rna-NM_001183164.1_AKU4011 | cds-NP_014073.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000074.1:68499-69509:+ | gene-YNL326C_BG1 | rna-NM_001183164.1_BG1 | cds-NP_014073.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:30228-31238:- | gene-YNL326C_Bruggeman | rna-NM_001183164.1_Bruggeman | cds-NP_014073.1_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:32856-33866:- | gene-YNL326C_CAT1 | rna-NM_001183164.1_CAT1 | cds-NP_014073.1_CAT1 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:21473-22483:- | gene-YNL326C_CBS1585 | rna-NM_001183164.1_CBS1585 | cds-NP_014073.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:21967-22977:- | gene-YNL326C_CBS436 | rna-NM_001183164.1_CBS436 | cds-NP_014073.1_CBS436 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:18130-19140:- | gene-YNL326C_CBS6412 | rna-NM_001183164.1_CBS6412 | cds-NP_014073.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:18319-19329:- | gene-YNL326C_CBS6413 | rna-NM_001183164.1_CBS6413 | cds-NP_014073.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:21166-22176:- | gene-YNL326C_CENPK1137D | rna-NM_001183164.1_CENPK1137D | cds-NP_014073.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:18165-19175:- | gene-YNL326C_EthanolRed | rna-NM_001183164.1_EthanolRed | cds-NP_014073.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:19064-20074:- | gene-YNL326C_FaliES1 | rna-NM_001183164.1_FaliES1 | cds-NP_014073.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000390.1:35456-36466:+ | gene-YNL326C_JAY291 | rna-NM_001183164.1_JAY291 | cds-NP_014073.1_JAY291 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:30510-31520:- | gene-YNL326C_MUCL30387 | rna-NM_001183164.1_MUCL30387 | cds-NP_014073.1_MUCL30387 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:23762-24772:- | gene-YNL326C_MUCL30388 | rna-NM_001183164.1_MUCL30388 | cds-NP_014073.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:19105-20115:- | gene-YNL326C_MUCL39482 | rna-NM_001183164.1_MUCL39482 | cds-NP_014073.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:20796-21806:- | gene-YNL326C_MUCL42920 | rna-NM_001183164.1_MUCL42920 | cds-NP_014073.1_MUCL42920 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:27306-28316:- | gene-YNL326C_NCIM3186 | rna-NM_001183164.1_NCIM3186 | cds-NP_014073.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:20439-21449:- | gene-YNL326C_NCYC1407 | rna-NM_001183164.1_NCYC1407 | cds-NP_014073.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:17632-18642:- | gene-YNL326C_PE2H3 | rna-NM_001183164.1_PE2H3 | cds-NP_014073.1_PE2H3 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:17020-18030:- | gene-YNL326C_PE2H4 | rna-NM_001183164.1_PE2H4 | cds-NP_014073.1_PE2H4 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:27337-28347:- | gene-YNL326C_S288C | rna-NM_001183164.1_S288C | cds-NP_014073.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000052.1:68874-69884:+ | gene-YNL326C_SA1 | rna-NM_001183164.1_SA1 | cds-NP_014073.1_SA1 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:19921-20931:- | gene-YNL326C_ThermosaccDry | rna-NM_001183164.1_ThermosaccDry | cds-NP_014073.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:32458-33468:- | gene-YNL326C_VR1 | rna-NM_001183164.1_VR1 | cds-NP_014073.1_VR1 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000029.1:11130-12140:- | gene-YNL326C_ZTW1 | rna-NM_001183164.1_ZTW1 | cds-NP_014073.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:29083-30093:- | gene-YNL326C_Sparadoxus | rna-NM_001183164.1_Sparadoxus | cds-NP_014073.1_Sparadoxus | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |