PEX6 (YNL329C)


Gene profile

Gene name: PEX6
Reference locus (S288C): YNL329C
Gene biotype: protein_coding

Description: Peroxisomal ATPase PEX6; AAA-peroxin; heterodimerizes with AAA-peroxin Pex1p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol; mutations in human PEX6 can lead to severe peroxisomal disorders and early death

Top 10 interactors (score): PEX1 (0.999); PEX13 (0.999); PEX15 (0.998); PEX5 (0.998); PEX14 (0.998); PEX12 (0.996); PEX10 (0.996); PEX19 (0.995); PEX7 (0.991); PEX2 (0.99); PEX3 (0.99); PEX11 (0.989); PEX17 (0.975); PEX4 (0.975); PEX8 (0.964); PRE7 (0.929); PEX22 (0.908); PEX18 (0.866); UBI4 (0.84); UBP15 (0.831)

Homologues (species, bitscore): PEX6 (Homo sapiens, 386.7); Pex6 (Mus musculus, 398.3); pex6 (Danio rerio, 375.2); vcp (Xenopus tropicalis, 270.4); Pex6 (Drosophila melanogaster, 309.7); prx-6 (Caenorhabditis elegans, 266.5); PEX6 (Arabidopsis thaliana, 416.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:13395-16487:- gene-YNL329C_AKU4011 rna-NM_001183167.1_AKU4011 cds-NP_014070.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000211.1:1070-4162:+ gene-YNL329C_BG1 rna-NM_001183167.1_BG1 cds-NP_014070.1_BG1 99.0 100.0 Mismatch 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:21859-24951:- gene-YNL329C_Bruggeman rna-NM_001183167.1_Bruggeman cds-NP_014070.1_Bruggeman 99.3 100.0 Mismatch 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:24937-28029:- gene-YNL329C_CAT1 rna-NM_001183167.1_CAT1 cds-NP_014070.1_CAT1 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:13791-16883:- gene-YNL329C_CBS1585 rna-NM_001183167.1_CBS1585 cds-NP_014070.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:14162-17254:- gene-YNL329C_CBS436 rna-NM_001183167.1_CBS436 cds-NP_014070.1_CBS436 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:10447-13539:- gene-YNL329C_CBS6412 rna-NM_001183167.1_CBS6412 cds-NP_014070.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:10409-13501:- gene-YNL329C_CBS6413 rna-NM_001183167.1_CBS6413 cds-NP_014070.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:13373-16465:- gene-YNL329C_CENPK1137D rna-NM_001183167.1_CENPK1137D cds-NP_014070.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:10255-13347:- gene-YNL329C_EthanolRed rna-NM_001183167.1_EthanolRed cds-NP_014070.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:11154-14246:- gene-YNL329C_FaliES1 rna-NM_001183167.1_FaliES1 cds-NP_014070.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000390.1:41179-44271:+ gene-YNL329C_JAY291 rna-NM_001183167.1_JAY291 cds-NP_014070.1_JAY291 99.1 100.0 Mismatch 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:22617-25806:- gene-YNL329C_MUCL30387 rna-NM_001183167.1_MUCL30387 cds-NP_014070.1_MUCL30387 96.3 100.0 Unannotated 1 1 0 False False False True False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:15967-19059:- gene-YNL329C_MUCL30388 rna-NM_001183167.1_MUCL30388 cds-NP_014070.1_MUCL30388 99.3 100.0 Mismatch 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:11195-14287:- gene-YNL329C_MUCL39482 rna-NM_001183167.1_MUCL39482 cds-NP_014070.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:12991-16083:- gene-YNL329C_MUCL42920 rna-NM_001183167.1_MUCL42920 cds-NP_014070.1_MUCL42920 99.1 100.0 Mismatch 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:19510-22602:- gene-YNL329C_NCIM3186 rna-NM_001183167.1_NCIM3186 cds-NP_014070.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:12529-15621:- gene-YNL329C_NCYC1407 rna-NM_001183167.1_NCYC1407 cds-NP_014070.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:9827-12919:- gene-YNL329C_PE2H3 rna-NM_001183167.1_PE2H3 cds-NP_014070.1_PE2H3 99.1 100.0 Mismatch 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:9215-12307:- gene-YNL329C_PE2H4 rna-NM_001183167.1_PE2H4 cds-NP_014070.1_PE2H4 99.1 100.0 Mismatch 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:19541-22633:- gene-YNL329C_S288C rna-NM_001183167.1_S288C cds-NP_014070.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000052.1:74711-77803:+ gene-YNL329C_SA1 rna-NM_001183167.1_SA1 cds-NP_014070.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:12011-15103:- gene-YNL329C_ThermosaccDry rna-NM_001183167.1_ThermosaccDry cds-NP_014070.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:24653-27745:- gene-YNL329C_VR1 rna-NM_001183167.1_VR1 cds-NP_014070.1_VR1 99.2 100.0 Mismatch 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000029.1:3221-6313:- gene-YNL329C_ZTW1 rna-NM_001183167.1_ZTW1 cds-NP_014070.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:21277-24369:- gene-YNL329C_Sparadoxus rna-NM_001183167.1_Sparadoxus cds-NP_014070.1_Sparadoxus 99.2 100.0 Verified 1 1 1 False True False False False

Additional files