PEX1 (YKL197C)


Gene profile

Gene name: PEX1
Reference locus (S288C): YKL197C
Gene biotype: protein_coding

Description: Peroxisomal ATPase PEX1; AAA-peroxin; heterodimerizes with AAA-peroxin Pex6p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol; induced by oleic acid and upregulated during anaerobiosis; mutations in human PEX1 can lead to severe peroxisomal disorders and early death

Top 10 interactors (score): PEX6 (0.999); PEX13 (0.997); PEX12 (0.994); PEX5 (0.993); PEX15 (0.993); PEX10 (0.982); PEX14 (0.982); PEX11 (0.98); PEX3 (0.979); PEX2 (0.974); PEX19 (0.966); PEX17 (0.941); PEX4 (0.94); PEX7 (0.918); FOX2 (0.909); PEX22 (0.894); UBI4 (0.834); PEX8 (0.828); PEX9 (0.827); PEX18 (0.82)

Homologues (species, bitscore): PEX1 (Homo sapiens, 357.5); Pex1 (Mus musculus, 356.7); pex1 (Danio rerio, 341.7); pex1 (Xenopus tropicalis, 357.1); Pex1 (Drosophila melanogaster, 293.1); prx-1 (Caenorhabditis elegans, 246.5); PEX1 (Arabidopsis thaliana, 321.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:57093-60224:- gene-YKL197C_AKU4011 rna-NM_001179763.1_AKU4011 cds-NP_012724.1_AKU4011 99.0 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000030.1:34055-37186:- gene-YKL197C_BG1 rna-NM_001179763.1_BG1 cds-NP_012724.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:74747-77878:- gene-YKL197C_Bruggeman rna-NM_001179763.1_Bruggeman cds-NP_012724.1_Bruggeman 99.2 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:69912-73043:- gene-YKL197C_CAT1 rna-NM_001179763.1_CAT1 cds-NP_012724.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:69078-72209:- gene-YKL197C_CBS1585 rna-NM_001179763.1_CBS1585 cds-NP_012724.1_CBS1585 99.0 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:68305-71436:- gene-YKL197C_CBS436 rna-NM_001179763.1_CBS436 cds-NP_012724.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:54335-57466:- gene-YKL197C_CBS6412 rna-NM_001179763.1_CBS6412 cds-NP_012724.1_CBS6412 99.0 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:69715-72846:- gene-YKL197C_CBS6413 rna-NM_001179763.1_CBS6413 cds-NP_012724.1_CBS6413 99.0 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:70509-73640:- gene-YKL197C_CENPK1137D rna-NM_001179763.1_CENPK1137D cds-NP_012724.1_CENPK1137D 99.0 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:68525-71656:- gene-YKL197C_EthanolRed rna-NM_001179763.1_EthanolRed cds-NP_012724.1_EthanolRed 99.0 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:68584-71715:- gene-YKL197C_FaliES1 rna-NM_001179763.1_FaliES1 cds-NP_012724.1_FaliES1 99.0 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000006.2:68138-71269:- gene-YKL197C_JAY291 rna-NM_001179763.1_JAY291 cds-NP_012724.1_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:77278-80409:- gene-YKL197C_MUCL30387 rna-NM_001179763.1_MUCL30387 cds-NP_012724.1_MUCL30387 99.0 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:71370-74501:- gene-YKL197C_MUCL30388 rna-NM_001179763.1_MUCL30388 cds-NP_012724.1_MUCL30388 99.1 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:69135-72266:- gene-YKL197C_MUCL39482 rna-NM_001179763.1_MUCL39482 cds-NP_012724.1_MUCL39482 99.0 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:72673-75804:- gene-YKL197C_MUCL42920 rna-NM_001179763.1_MUCL42920 cds-NP_012724.1_MUCL42920 99.3 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:70723-73854:- gene-YKL197C_NCIM3186 rna-NM_001179763.1_NCIM3186 cds-NP_012724.1_NCIM3186 98.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:69159-72290:- gene-YKL197C_NCYC1407 rna-NM_001179763.1_NCYC1407 cds-NP_012724.1_NCYC1407 99.0 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:76678-79809:- gene-YKL197C_PE2H3 rna-NM_001179763.1_PE2H3 cds-NP_012724.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:72972-76103:- gene-YKL197C_PE2H4 rna-NM_001179763.1_PE2H4 cds-NP_012724.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:70734-73865:- gene-YKL197C_S288C rna-NM_001179763.1_S288C cds-NP_012724.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000113.1:4607-7738:- gene-YKL197C_SA1 rna-NM_001179763.1_SA1 cds-NP_012724.1_SA1 99.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:69332-72463:- gene-YKL197C_ThermosaccDry rna-NM_001179763.1_ThermosaccDry cds-NP_012724.1_ThermosaccDry 99.0 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:68384-71515:- gene-YKL197C_VR1 rna-NM_001179763.1_VR1 cds-NP_012724.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:68253-71384:- gene-YKL197C_ZTW1 rna-NM_001179763.1_ZTW1 cds-NP_012724.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:76890-80021:- gene-YKL197C_Sparadoxus rna-NM_001179763.1_Sparadoxus cds-NP_012724.1_Sparadoxus 87.1 99.7 Verified 1 1 1 False True False False False

Additional files