PER33 (YLR064W)


Gene profile

Gene name: PER33
Reference locus (S288C): YLR064W
Gene biotype: protein_coding

Description: Protein that localizes to the endoplasmic reticulum; also associates with the nuclear pore complex; deletion extends chronological lifespan; highly conserved across species, orthologous to human TMEM33 and paralogous to Pom33p; protein abundance increases in response to DNA replication stress; Belongs to the PER33/POM33 family

Top 10 interactors (score): RTN1 (0.818); EMP65 (0.755); RTN2 (0.728); SEY1 (0.723); HEH2 (0.698); YOP1 (0.675); YET2 (0.659); ASI3 (0.617); ASI1 (0.616); ASI2 (0.616); LCL2 (0.593); TYS1 (0.581); IRC23 (0.575); SOP4 (0.572); APQ12 (0.571); NUP159 (0.571); FMP16 (0.571); YJR039W (0.563); NUP170 (0.557); POM33 (0.532)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:247928-248749:+ gene-YLR064W_AKU4011 rna-NM_001181951.1_AKU4011 cds-NP_013165.1_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000212.1:211069-211890:+ gene-YLR064W_BG1 rna-NM_001181951.1_BG1 cds-NP_013165.1_BG1 99.5 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:257837-258658:+ gene-YLR064W_Bruggeman rna-NM_001181951.1_Bruggeman cds-NP_013165.1_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:258154-258975:+ gene-YLR064W_CAT1 rna-NM_001181951.1_CAT1 cds-NP_013165.1_CAT1 99.6 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:255044-255865:+ gene-YLR064W_CBS1585 rna-NM_001181951.1_CBS1585 cds-NP_013165.1_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:245666-246487:+ gene-YLR064W_CBS436 rna-NM_001181951.1_CBS436 cds-NP_013165.1_CBS436 99.6 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:253482-254303:+ gene-YLR064W_CBS6412 rna-NM_001181951.1_CBS6412 cds-NP_013165.1_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:255315-256136:+ gene-YLR064W_CBS6413 rna-NM_001181951.1_CBS6413 cds-NP_013165.1_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:250478-251299:+ gene-YLR064W_CENPK1137D rna-NM_001181951.1_CENPK1137D cds-NP_013165.1_CENPK1137D 99.7 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:247449-248270:+ gene-YLR064W_EthanolRed rna-NM_001181951.1_EthanolRed cds-NP_013165.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:247325-248146:+ gene-YLR064W_FaliES1 rna-NM_001181951.1_FaliES1 cds-NP_013165.1_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000129.1:22260-23081:+ gene-YLR064W_JAY291 rna-NM_001181951.1_JAY291 cds-NP_013165.1_JAY291 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:255206-256027:+ gene-YLR064W_MUCL30387 rna-NM_001181951.1_MUCL30387 cds-NP_013165.1_MUCL30387 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:262849-263670:+ gene-YLR064W_MUCL30388 rna-NM_001181951.1_MUCL30388 cds-NP_013165.1_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:255555-256376:+ gene-YLR064W_MUCL39482 rna-NM_001181951.1_MUCL39482 cds-NP_013165.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:255476-256297:+ gene-YLR064W_MUCL42920 rna-NM_001181951.1_MUCL42920 cds-NP_013165.1_MUCL42920 99.7 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:265430-266251:+ gene-YLR064W_NCIM3186 rna-NM_001181951.1_NCIM3186 cds-NP_013165.1_NCIM3186 99.6 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:247630-248451:+ gene-YLR064W_NCYC1407 rna-NM_001181951.1_NCYC1407 cds-NP_013165.1_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:253497-254318:+ gene-YLR064W_PE2H3 rna-NM_001181951.1_PE2H3 cds-NP_013165.1_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:253238-254059:+ gene-YLR064W_PE2H4 rna-NM_001181951.1_PE2H4 cds-NP_013165.1_PE2H4 99.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:265456-266277:+ gene-YLR064W_S288C rna-NM_001181951.1_S288C cds-NP_013165.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000033.1:107913-108734:- gene-YLR064W_SA1 rna-NM_001181951.1_SA1 cds-NP_013165.1_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:247501-248322:+ gene-YLR064W_ThermosaccDry rna-NM_001181951.1_ThermosaccDry cds-NP_013165.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:261190-262011:+ gene-YLR064W_VR1 rna-NM_001181951.1_VR1 cds-NP_013165.1_VR1 99.6 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000023.1:246888-247709:+ gene-YLR064W_ZTW1 rna-NM_001181951.1_ZTW1 cds-NP_013165.1_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:255768-256589:+ gene-YLR064W_Sparadoxus rna-NM_001181951.1_Sparadoxus cds-NP_013165.1_Sparadoxus 92.8 100.0 Verified 1 1 1 False True False False False

Additional files