PEP7 (YDR323C)


Gene profile

Gene name: PEP7
Reference locus (S288C): YDR323C
Gene biotype: protein_coding

Description: Adaptor protein involved in vesicle-mediated vacuolar protein sorting; multivalent adaptor protein; facilitates vesicle-mediated vacuolar protein sorting by ensuring high-fidelity vesicle docking and fusion, which are essential for targeting of vesicles to the endosome; required for vacuole inheritance

Top 10 interactors (score): VPS45 (0.999); VPS21 (0.997); FAB1 (0.992); YPT52 (0.987); PEP12 (0.981); YPT53 (0.954); VPS27 (0.954); YPT7 (0.953); PEP3 (0.95); VPS9 (0.942); PEP5 (0.938); VPS34 (0.938); VPS8 (0.918); VPS3 (0.915); VPS33 (0.912); SEC1 (0.908); VPS16 (0.901); YPT10 (0.888); VAM6 (0.859); VPS41 (0.859)

Homologues (species, bitscore): ZFYVE20 (Homo sapiens, 68.9); Zfyve20 (Mus musculus, 71.6); LOC569240 (Danio rerio, 65.1); zfyve20 (Xenopus tropicalis, 73.9); Rbsn-5 (Drosophila melanogaster, 71.2); rabs-5 (Caenorhabditis elegans, 62.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:1058505-1060052:- gene-YDR323C_AKU4011 rna-NM_001180631.3_AKU4011 cds-NP_010610.3_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:71495-73042:+ gene-YDR323C_BG1 rna-NM_001180631.3_BG1 cds-NP_010610.3_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1086047-1087594:- gene-YDR323C_Bruggeman rna-NM_001180631.3_Bruggeman cds-NP_010610.3_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1072806-1074353:- gene-YDR323C_CAT1 rna-NM_001180631.3_CAT1 cds-NP_010610.3_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1052949-1054496:- gene-YDR323C_CBS1585 rna-NM_001180631.3_CBS1585 cds-NP_010610.3_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1071345-1072892:- gene-YDR323C_CBS436 rna-NM_001180631.3_CBS436 cds-NP_010610.3_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1049637-1051184:- gene-YDR323C_CBS6412 rna-NM_001180631.3_CBS6412 cds-NP_010610.3_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1070868-1072415:- gene-YDR323C_CBS6413 rna-NM_001180631.3_CBS6413 cds-NP_010610.3_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1111118-1112665:- gene-YDR323C_CENPK1137D rna-NM_001180631.3_CENPK1137D cds-NP_010610.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:234047-235594:- gene-YDR323C_EthanolRed rna-NM_001180631.3_EthanolRed cds-NP_010610.3_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1065262-1066809:- gene-YDR323C_FaliES1 rna-NM_001180631.3_FaliES1 cds-NP_010610.3_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000386.1:17786-19333:- gene-YDR323C_JAY291 rna-NM_001180631.3_JAY291 cds-NP_010610.3_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1071308-1072855:- gene-YDR323C_MUCL30387 rna-NM_001180631.3_MUCL30387 cds-NP_010610.3_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1060243-1061790:- gene-YDR323C_MUCL30388 rna-NM_001180631.3_MUCL30388 cds-NP_010610.3_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1044756-1046303:- gene-YDR323C_MUCL39482 rna-NM_001180631.3_MUCL39482 cds-NP_010610.3_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:991839-993386:- gene-YDR323C_MUCL42920 rna-NM_001180631.3_MUCL42920 cds-NP_010610.3_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1112403-1113950:- gene-YDR323C_NCIM3186 rna-NM_001180631.3_NCIM3186 cds-NP_010610.3_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1058047-1059594:- gene-YDR323C_NCYC1407 rna-NM_001180631.3_NCYC1407 cds-NP_010610.3_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1069064-1070611:- gene-YDR323C_PE2H3 rna-NM_001180631.3_PE2H3 cds-NP_010610.3_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1074649-1076196:- gene-YDR323C_PE2H4 rna-NM_001180631.3_PE2H4 cds-NP_010610.3_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1112480-1114027:- gene-YDR323C_S288C rna-NM_001180631.3_S288C cds-NP_010610.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000025.1:83293-84840:- gene-YDR323C_SA1 rna-NM_001180631.3_SA1 cds-NP_010610.3_SA1 99.3 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1069535-1071082:- gene-YDR323C_ThermosaccDry rna-NM_001180631.3_ThermosaccDry cds-NP_010610.3_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:1085462-1087009:- gene-YDR323C_VR1 rna-NM_001180631.3_VR1 cds-NP_010610.3_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:113644-115191:- gene-YDR323C_ZTW1 rna-NM_001180631.3_ZTW1 cds-NP_010610.3_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1064970-1066517:- gene-YDR323C_Sparadoxus rna-NM_001180631.3_Sparadoxus cds-NP_010610.3_Sparadoxus 89.4 99.9 Verified 1 1 1 False True False False False

Additional files