Gene name: PEP5
Reference locus (S288C): YMR231W
Gene biotype: protein_coding
Description: Histone E3 ligase, component of CORVET membrane tethering complex; peripheral vacuolar membrane protein required for protein trafficking and vacuole biogenesis; interacts with Pep7p; involved in ubiquitination and degradation of excess histones; Belongs to the VPS11 family
Top 10 interactors (score): PEP3 (0.999); VAM7 (0.999); VAM6 (0.999); VPS33 (0.999); VPS21 (0.999); VPS41 (0.999); VPS16 (0.999); VPS8 (0.999); YPT7 (0.999); VAM3 (0.999); VPS3 (0.999); VTI1 (0.994); VPS45 (0.988); MON1 (0.986); YPT52 (0.974); SEC1 (0.945); VPS34 (0.943); PEP7 (0.938); YPT11 (0.928); YKT6 (0.893)
Homologues (species, bitscore): VPS11 (Homo sapiens, 209.1); Vps11 (Mus musculus, 213.8); vps11 (Danio rerio, 236.5); vps11 (Xenopus tropicalis, 184.5); vps-11 (Caenorhabditis elegans, 79.3); VPS11 (Arabidopsis thaliana, 168.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:773451-776540:+ | gene-YMR231W_AKU4011 | rna-NM_001182738.1_AKU4011 | cds-NP_013958.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:178050-181139:- | gene-YMR231W_BG1 | rna-NM_001182738.1_BG1 | cds-NP_013958.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:717678-720767:+ | gene-YMR231W_Bruggeman | rna-NM_001182738.1_Bruggeman | cds-NP_013958.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:721571-724660:+ | gene-YMR231W_CAT1 | rna-NM_001182738.1_CAT1 | cds-NP_013958.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:705711-708800:+ | gene-YMR231W_CBS1585 | rna-NM_001182738.1_CBS1585 | cds-NP_013958.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:709980-713069:+ | gene-YMR231W_CBS436 | rna-NM_001182738.1_CBS436 | cds-NP_013958.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:817273-820362:+ | gene-YMR231W_CBS6412 | rna-NM_001182738.1_CBS6412 | cds-NP_013958.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:704863-707952:+ | gene-YMR231W_CBS6413 | rna-NM_001182738.1_CBS6413 | cds-NP_013958.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:728288-731377:+ | gene-YMR231W_CENPK1137D | rna-NM_001182738.1_CENPK1137D | cds-NP_013958.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:765918-769007:+ | gene-YMR231W_EthanolRed | rna-NM_001182738.1_EthanolRed | cds-NP_013958.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:711570-714659:+ | gene-YMR231W_FaliES1 | rna-NM_001182738.1_FaliES1 | cds-NP_013958.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000141.1:71359-74448:- | gene-YMR231W_JAY291 | rna-NM_001182738.1_JAY291 | cds-NP_013958.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:711462-714551:+ | gene-YMR231W_MUCL30387 | rna-NM_001182738.1_MUCL30387 | cds-NP_013958.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:718689-721778:+ | gene-YMR231W_MUCL30388 | rna-NM_001182738.1_MUCL30388 | cds-NP_013958.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:706781-709870:+ | gene-YMR231W_MUCL39482 | rna-NM_001182738.1_MUCL39482 | cds-NP_013958.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:714126-717215:+ | gene-YMR231W_MUCL42920 | rna-NM_001182738.1_MUCL42920 | cds-NP_013958.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:733499-736588:+ | gene-YMR231W_NCIM3186 | rna-NM_001182738.1_NCIM3186 | cds-NP_013958.1_NCIM3186 | 90.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:706438-709527:+ | gene-YMR231W_NCYC1407 | rna-NM_001182738.1_NCYC1407 | cds-NP_013958.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:716318-719407:+ | gene-YMR231W_PE2H3 | rna-NM_001182738.1_PE2H3 | cds-NP_013958.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:717336-720425:+ | gene-YMR231W_PE2H4 | rna-NM_001182738.1_PE2H4 | cds-NP_013958.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:733545-736634:+ | gene-YMR231W_S288C | rna-NM_001182738.1_S288C | cds-NP_013958.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:71474-74563:- | gene-YMR231W_SA1 | rna-NM_001182738.1_SA1 | cds-NP_013958.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:707741-710830:+ | gene-YMR231W_ThermosaccDry | rna-NM_001182738.1_ThermosaccDry | cds-NP_013958.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:720853-723942:+ | gene-YMR231W_VR1 | rna-NM_001182738.1_VR1 | cds-NP_013958.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000028.1:123445-126534:+ | gene-YMR231W_ZTW1 | rna-NM_001182738.1_ZTW1 | cds-NP_013958.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:725603-728692:+ | gene-YMR231W_Sparadoxus | rna-NM_001182738.1_Sparadoxus | cds-NP_013958.1_Sparadoxus | 89.6 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |