PEP1 (YBL017C)


Gene profile

Gene name: PEP1
Reference locus (S288C): YBL017C
Gene biotype: protein_coding

Description: Vacuolar protein sorting/targeting protein VPS10; Type I transmembrane sorting receptor for multiple vacuolar hydrolases; cycles between the late-Golgi and prevacuolar endosome-like compartments; Belongs to the VPS10-related sortilin family

Top 10 interactors (score): VPS35 (0.996); PRC1 (0.995); PEP8 (0.988); VPS5 (0.97); VPS29 (0.951); KEX2 (0.94); VPS17 (0.916); SNX3 (0.898); STE13 (0.896); VPS27 (0.884); PEP4 (0.859); GGA2 (0.857); PEP12 (0.857); VPH1 (0.842); CHC1 (0.841); VPS21 (0.837); MRL1 (0.833); YPT7 (0.83); VPS13 (0.816); VTI1 (0.814)

Homologues (species, bitscore): SORCS2 (Homo sapiens, 167.2); Sorl1 (Mus musculus, 165.6); sorl1 (Danio rerio, 176.8); sorl1 (Xenopus tropicalis, 161.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:180455-185194:- gene-YBL017C_AKU4011 rna-NM_001178257.1_AKU4011 cds-NP_009536.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000179.1:171281-176014:- gene-YBL017C_BG1 rna-NM_001178257.1_BG1 cds-NP_009536.1_BG1 98.8 99.8 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:181041-185780:- gene-YBL017C_Bruggeman rna-NM_001178257.1_Bruggeman cds-NP_009536.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:183650-188383:- gene-YBL017C_CAT1 rna-NM_001178257.1_CAT1 cds-NP_009536.1_CAT1 98.8 99.8 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:173010-177749:- gene-YBL017C_CBS1585 rna-NM_001178257.1_CBS1585 cds-NP_009536.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:181463-186196:- gene-YBL017C_CBS436 rna-NM_001178257.1_CBS436 cds-NP_009536.1_CBS436 98.8 99.8 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:271789-276528:- gene-YBL017C_CBS6412 rna-NM_001178257.1_CBS6412 cds-NP_009536.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:178580-183319:- gene-YBL017C_CBS6413 rna-NM_001178257.1_CBS6413 cds-NP_009536.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:180609-185348:- gene-YBL017C_CENPK1137D rna-NM_001178257.1_CENPK1137D cds-NP_009536.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:307997-312736:- gene-YBL017C_EthanolRed rna-NM_001178257.1_EthanolRed cds-NP_009536.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:195263-200002:- gene-YBL017C_FaliES1 rna-NM_001178257.1_FaliES1 cds-NP_009536.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000421.1:20932-25665:- gene-YBL017C_JAY291 rna-NM_001178257.1_JAY291 cds-NP_009536.1_JAY291 98.8 99.8 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:180898-185631:- gene-YBL017C_MUCL30387 rna-NM_001178257.1_MUCL30387 cds-NP_009536.1_MUCL30387 98.8 99.8 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:181940-186679:- gene-YBL017C_MUCL30388 rna-NM_001178257.1_MUCL30388 cds-NP_009536.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:173195-177934:- gene-YBL017C_MUCL39482 rna-NM_001178257.1_MUCL39482 cds-NP_009536.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:180470-185203:- gene-YBL017C_MUCL42920 rna-NM_001178257.1_MUCL42920 cds-NP_009536.1_MUCL42920 98.9 99.8 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:186641-191380:- gene-YBL017C_NCIM3186 rna-NM_001178257.1_NCIM3186 cds-NP_009536.1_NCIM3186 96.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:174344-179083:- gene-YBL017C_NCYC1407 rna-NM_001178257.1_NCYC1407 cds-NP_009536.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:180569-185302:- gene-YBL017C_PE2H3 rna-NM_001178257.1_PE2H3 cds-NP_009536.1_PE2H3 98.8 99.8 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:178213-182946:- gene-YBL017C_PE2H4 rna-NM_001178257.1_PE2H4 cds-NP_009536.1_PE2H4 98.8 99.8 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:186844-191583:- gene-YBL017C_S288C rna-NM_001178257.1_S288C cds-NP_009536.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000051.1:71565-76298:- gene-YBL017C_SA1 rna-NM_001178257.1_SA1 cds-NP_009536.1_SA1 98.8 99.8 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:195218-199957:- gene-YBL017C_ThermosaccDry rna-NM_001178257.1_ThermosaccDry cds-NP_009536.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:177382-182115:- gene-YBL017C_VR1 rna-NM_001178257.1_VR1 cds-NP_009536.1_VR1 98.8 99.8 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:171929-176668:- gene-YBL017C_ZTW1 rna-NM_001178257.1_ZTW1 cds-NP_009536.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:206863-211608:- gene-YBL017C_Sparadoxus rna-NM_001178257.1_Sparadoxus cds-NP_009536.1_Sparadoxus 87.6 100.0 Unannotated 1 1 0 False False False False True

Additional files