PEA2 (YER149C)


Gene profile

Gene name: PEA2
Reference locus (S288C): YER149C
Gene biotype: protein_coding

Description: Protein PEA2; Coiled-coil 12S polarisome subunit; required for polarity establishment, apical bud growth, shmoo formation, filamentous differentiation; involved in Bni1p localization at sites of polarized growth, controlling polarized assembly of actin cables; role in apical growth affects diploid-specific bipolar bud site selection; retains Slt2p at bud tip to regulate ER inheritance; role in Ca2+ influx, cell fusion; S288C allele encoding Leu409 rather than Met linked with non-invasion

Top 10 interactors (score): BUD6 (0.999); SPA2 (0.999); BNI1 (0.997); MSB3 (0.981); MSB4 (0.971); FUS1 (0.889); EPO1 (0.886); CLA4 (0.86); FUS2 (0.835); CDC42 (0.805); ACT1 (0.797); BNR1 (0.794); CDC24 (0.718); SCS2 (0.718); RVS161 (0.714); BEM1 (0.713); TPM1 (0.687); BEM3 (0.666); AXL1 (0.65); FUS3 (0.65)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:453714-454976:- gene-YER149C_AKU4011 rna-NM_001179039.1_AKU4011 cds-NP_011076.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000176.1:89586-90848:+ gene-YER149C_BG1 rna-NM_001179039.1_BG1 cds-NP_011076.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:465002-466264:- gene-YER149C_Bruggeman rna-NM_001179039.1_Bruggeman cds-NP_011076.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:452837-454099:- gene-YER149C_CAT1 rna-NM_001179039.1_CAT1 cds-NP_011076.1_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:453531-454793:- gene-YER149C_CBS1585 rna-NM_001179039.1_CBS1585 cds-NP_011076.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:457337-458599:- gene-YER149C_CBS436 rna-NM_001179039.1_CBS436 cds-NP_011076.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:452044-453306:- gene-YER149C_CBS6412 rna-NM_001179039.1_CBS6412 cds-NP_011076.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:459590-460852:- gene-YER149C_CBS6413 rna-NM_001179039.1_CBS6413 cds-NP_011076.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:463981-465243:- gene-YER149C_CENPK1137D rna-NM_001179039.1_CENPK1137D cds-NP_011076.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:460003-461265:- gene-YER149C_EthanolRed rna-NM_001179039.1_EthanolRed cds-NP_011076.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:460589-461851:- gene-YER149C_FaliES1 rna-NM_001179039.1_FaliES1 cds-NP_011076.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000111.1:24638-25900:+ gene-YER149C_JAY291 rna-NM_001179039.1_JAY291 cds-NP_011076.1_JAY291 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:453742-455004:- gene-YER149C_MUCL30387 rna-NM_001179039.1_MUCL30387 cds-NP_011076.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:456642-457904:- gene-YER149C_MUCL30388 rna-NM_001179039.1_MUCL30388 cds-NP_011076.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:449483-450745:- gene-YER149C_MUCL39482 rna-NM_001179039.1_MUCL39482 cds-NP_011076.1_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:461561-462823:- gene-YER149C_MUCL42920 rna-NM_001179039.1_MUCL42920 cds-NP_011076.1_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:466207-467469:- gene-YER149C_NCIM3186 rna-NM_001179039.1_NCIM3186 cds-NP_011076.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:458954-460216:- gene-YER149C_NCYC1407 rna-NM_001179039.1_NCYC1407 cds-NP_011076.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:474638-475900:- gene-YER149C_PE2H3 rna-NM_001179039.1_PE2H3 cds-NP_011076.1_PE2H3 99.9 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:464579-465841:- gene-YER149C_PE2H4 rna-NM_001179039.1_PE2H4 cds-NP_011076.1_PE2H4 99.9 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:466208-467470:- gene-YER149C_S288C rna-NM_001179039.1_S288C cds-NP_011076.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000030.1:24108-25370:- gene-YER149C_SA1 rna-NM_001179039.1_SA1 cds-NP_011076.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:461389-462651:- gene-YER149C_ThermosaccDry rna-NM_001179039.1_ThermosaccDry cds-NP_011076.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:454502-455764:- gene-YER149C_VR1 rna-NM_001179039.1_VR1 cds-NP_011076.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000010.1:16344-17606:- gene-YER149C_ZTW1 rna-NM_001179039.1_ZTW1 cds-NP_011076.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:462222-463484:- gene-YER149C_Sparadoxus rna-NM_001179039.1_Sparadoxus cds-NP_011076.1_Sparadoxus 87.4 100.0 Verified 1 1 1 False True False False False

Additional files