Gene name: PDX1
Reference locus (S288C): YGR193C
Gene biotype: protein_coding
Description: E3-binding protein of the mitochondrial pyruvate dehydrogenase complex; plays a structural role in the complex by binding and positioning dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide acetyltransferase (E2) core
Top 10 interactors (score): PDA1 (0.999); PDB1 (0.999); LPD1 (0.999); KGD2 (0.995); IRC15 (0.965); KGD1 (0.958); LAT1 (0.954); LSC1 (0.876); AIM22 (0.854); CIT2 (0.832); CYM1 (0.822); GCV3 (0.82); LIP2 (0.815); CTP1 (0.794); CIT1 (0.754); LSC2 (0.753); CIT3 (0.73); ACO1 (0.73); FUM1 (0.712); SDH2 (0.71)
Homologues (species, bitscore): PDHX (Homo sapiens, 85.9); Pdhx (Mus musculus, 85.9); pdhx (Danio rerio, 86.7); pdhx (Xenopus tropicalis, 91.3); CG5261 (Drosophila melanogaster, 76.3); dlat-1 (Caenorhabditis elegans, 92.4); LTA3 (Arabidopsis thaliana, 94.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:850025-851257:- | gene-YGR193C_AKU4011 | rna-NM_001181322.1_AKU4011 | cds-NP_011709.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:130360-131592:- | gene-YGR193C_BG1 | rna-NM_001181322.1_BG1 | cds-NP_011709.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:858219-859451:- | gene-YGR193C_Bruggeman | rna-NM_001181322.1_Bruggeman | cds-NP_011709.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:856232-857464:- | gene-YGR193C_CAT1 | rna-NM_001181322.1_CAT1 | cds-NP_011709.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:853467-854699:- | gene-YGR193C_CBS1585 | rna-NM_001181322.1_CBS1585 | cds-NP_011709.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:856826-858058:- | gene-YGR193C_CBS436 | rna-NM_001181322.1_CBS436 | cds-NP_011709.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:844338-845570:- | gene-YGR193C_CBS6412 | rna-NM_001181322.1_CBS6412 | cds-NP_011709.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:850396-851628:- | gene-YGR193C_CBS6413 | rna-NM_001181322.1_CBS6413 | cds-NP_011709.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:884235-885467:- | gene-YGR193C_CENPK1137D | rna-NM_001181322.1_CENPK1137D | cds-NP_011709.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:838846-840078:- | gene-YGR193C_EthanolRed | rna-NM_001181322.1_EthanolRed | cds-NP_011709.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:843237-844469:- | gene-YGR193C_FaliES1 | rna-NM_001181322.1_FaliES1 | cds-NP_011709.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000148.1:969-2201:- | gene-YGR193C_JAY291 | rna-NM_001181322.1_JAY291 | cds-NP_011709.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:855709-856941:- | gene-YGR193C_MUCL30387 | rna-NM_001181322.1_MUCL30387 | cds-NP_011709.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:855395-856627:- | gene-YGR193C_MUCL30388 | rna-NM_001181322.1_MUCL30388 | cds-NP_011709.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:848540-849772:- | gene-YGR193C_MUCL39482 | rna-NM_001181322.1_MUCL39482 | cds-NP_011709.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:866092-867324:- | gene-YGR193C_MUCL42920 | rna-NM_001181322.1_MUCL42920 | cds-NP_011709.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:884509-885741:- | gene-YGR193C_NCIM3186 | rna-NM_001181322.1_NCIM3186 | cds-NP_011709.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:844198-845430:- | gene-YGR193C_NCYC1407 | rna-NM_001181322.1_NCYC1407 | cds-NP_011709.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:868809-870041:- | gene-YGR193C_PE2H3 | rna-NM_001181322.1_PE2H3 | cds-NP_011709.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:873919-875151:- | gene-YGR193C_PE2H4 | rna-NM_001181322.1_PE2H4 | cds-NP_011709.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:884509-885741:- | gene-YGR193C_S288C | rna-NM_001181322.1_S288C | cds-NP_011709.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000101.1:5960-7192:- | gene-YGR193C_SA1 | rna-NM_001181322.1_SA1 | cds-NP_011709.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:863748-864980:- | gene-YGR193C_ThermosaccDry | rna-NM_001181322.1_ThermosaccDry | cds-NP_011709.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:968239-969471:- | gene-YGR193C_VR1 | rna-NM_001181322.1_VR1 | cds-NP_011709.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:165194-166426:- | gene-YGR193C_ZTW1 | rna-NM_001181322.1_ZTW1 | cds-NP_011709.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:856037-857290:- | gene-YGR193C_Sparadoxus | rna-NM_001181322.1_Sparadoxus | cds-NP_011709.1_Sparadoxus | 88.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |