Gene name: PDS5
Reference locus (S288C): YMR076C
Gene biotype: protein_coding
Description: Cohesion maintenance factor; involved in sister chromatid condensation and cohesion; colocalizes with cohesin on chromosomes; performs its cohesin maintenance function in pre-anaphase cells by protecting the integrity of the cohesion complex; also required during meiosis; relocalizes to the cytosol in response to hypoxia
Top 10 interactors (score): SCC2 (0.999); SMC1 (0.999); ECO1 (0.999); IRR1 (0.999); SMC3 (0.999); MCD1 (0.999); RAD61 (0.998); SMC4 (0.997); ESP1 (0.997); CDC5 (0.993); YCG1 (0.99); RAD30 (0.983); SMC5 (0.98); TOP2 (0.976); QRI7 (0.97); SMC6 (0.962); YCS4 (0.96); ELG1 (0.952); SCC4 (0.948); CTF18 (0.943)
Homologues (species, bitscore): PDS5A (Homo sapiens, 137.1); Pds5b (Mus musculus, 144.4); pds5b (Danio rerio, 139.8); pds5b (Xenopus tropicalis, 128.3); pds5 (Drosophila melanogaster, 112.5); evl-14 (Caenorhabditis elegans, 54.3); AT5G47690 (Arabidopsis thaliana, 117.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:453901-457734:- | gene-YMR076C_AKU4011 | rna-NM_001182575.1_AKU4011 | cds-NP_013793.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:85049-88882:+ | gene-YMR076C_BG1 | rna-NM_001182575.1_BG1 | cds-NP_013793.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:396052-399885:- | gene-YMR076C_Bruggeman | rna-NM_001182575.1_Bruggeman | cds-NP_013793.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:396415-400248:- | gene-YMR076C_CAT1 | rna-NM_001182575.1_CAT1 | cds-NP_013793.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:386841-390674:- | gene-YMR076C_CBS1585 | rna-NM_001182575.1_CBS1585 | cds-NP_013793.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:392397-396230:- | gene-YMR076C_CBS436 | rna-NM_001182575.1_CBS436 | cds-NP_013793.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:499917-503750:- | gene-YMR076C_CBS6412 | rna-NM_001182575.1_CBS6412 | cds-NP_013793.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:386098-389931:- | gene-YMR076C_CBS6413 | rna-NM_001182575.1_CBS6413 | cds-NP_013793.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:410302-414134:- | gene-YMR076C_CENPK1137D | rna-NM_001182575.1_CENPK1137D | cds-NP_013793.1_CENPK1137D | 99.9 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:386707-390540:- | gene-YMR076C_EthanolRed | rna-NM_001182575.1_EthanolRed | cds-NP_013793.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:389873-393706:- | gene-YMR076C_FaliES1 | rna-NM_001182575.1_FaliES1 | cds-NP_013793.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000033.1:43250-47083:+ | gene-YMR076C_JAY291 | rna-NM_001182575.1_JAY291 | cds-NP_013793.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:391788-395621:- | gene-YMR076C_MUCL30387 | rna-NM_001182575.1_MUCL30387 | cds-NP_013793.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:396472-400305:- | gene-YMR076C_MUCL30388 | rna-NM_001182575.1_MUCL30388 | cds-NP_013793.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:387129-390962:- | gene-YMR076C_MUCL39482 | rna-NM_001182575.1_MUCL39482 | cds-NP_013793.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:393789-397622:- | gene-YMR076C_MUCL42920 | rna-NM_001182575.1_MUCL42920 | cds-NP_013793.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:416150-419983:- | gene-YMR076C_NCIM3186 | rna-NM_001182575.1_NCIM3186 | cds-NP_013793.1_NCIM3186 | 86.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:387044-390877:- | gene-YMR076C_NCYC1407 | rna-NM_001182575.1_NCYC1407 | cds-NP_013793.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:392996-396829:- | gene-YMR076C_PE2H3 | rna-NM_001182575.1_PE2H3 | cds-NP_013793.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:399091-402924:- | gene-YMR076C_PE2H4 | rna-NM_001182575.1_PE2H4 | cds-NP_013793.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:416196-420029:- | gene-YMR076C_S288C | rna-NM_001182575.1_S288C | cds-NP_013793.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:130140-133973:+ | gene-YMR076C_SA1 | rna-NM_001182575.1_SA1 | cds-NP_013793.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:387676-391509:- | gene-YMR076C_ThermosaccDry | rna-NM_001182575.1_ThermosaccDry | cds-NP_013793.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:399581-403414:- | gene-YMR076C_VR1 | rna-NM_001182575.1_VR1 | cds-NP_013793.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:363951-367784:- | gene-YMR076C_ZTW1 | rna-NM_001182575.1_ZTW1 | cds-NP_013793.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:399492-403328:- | gene-YMR076C_Sparadoxus | rna-NM_001182575.1_Sparadoxus | cds-NP_013793.1_Sparadoxus | 89.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |