PDS1 (YDR113C)


Gene profile

Gene name: PDS1
Reference locus (S288C): YDR113C
Gene biotype: protein_coding

Description: Securin; inhibits anaphase by binding separin Esp1p; blocks cyclin destruction and mitotic exit, essential for meiotic progression and mitotic cell cycle arrest; localization is cell-cycle dependent and regulated by Cdc28p phosphorylation; Belongs to the securin family

Top 10 interactors (score): CDC20 (0.999); ESP1 (0.999); CHK1 (0.984); CDH1 (0.979); CDC28 (0.963); CDC23 (0.959); CLB2 (0.955); CIN8 (0.95); MCD1 (0.947); SLK19 (0.944); CDC16 (0.933); CLB5 (0.929); CDC14 (0.923); CDC27 (0.92); RAD53 (0.911); ASE1 (0.908); KIP1 (0.908); MAD2 (0.9); CDC15 (0.87); DUN1 (0.861)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:651426-652547:- gene-YDR113C_AKU4011 rna-NM_001180421.3_AKU4011 cds-NP_010398.3_AKU4011 98.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:472333-473457:+ gene-YDR113C_BG1 rna-NM_001180421.3_BG1 cds-NP_010398.3_BG1 98.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:683489-684610:- gene-YDR113C_Bruggeman rna-NM_001180421.3_Bruggeman cds-NP_010398.3_Bruggeman 99.0 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:670229-671350:- gene-YDR113C_CAT1 rna-NM_001180421.3_CAT1 cds-NP_010398.3_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:642464-643585:- gene-YDR113C_CBS1585 rna-NM_001180421.3_CBS1585 cds-NP_010398.3_CBS1585 99.1 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:668352-669473:- gene-YDR113C_CBS436 rna-NM_001180421.3_CBS436 cds-NP_010398.3_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:638816-639937:- gene-YDR113C_CBS6412 rna-NM_001180421.3_CBS6412 cds-NP_010398.3_CBS6412 98.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:667793-668914:- gene-YDR113C_CBS6413 rna-NM_001180421.3_CBS6413 cds-NP_010398.3_CBS6413 98.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:672936-674057:- gene-YDR113C_CENPK1137D rna-NM_001180421.3_CENPK1137D cds-NP_010398.3_CENPK1137D 99.9 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:653197-654318:- gene-YDR113C_EthanolRed rna-NM_001180421.3_EthanolRed cds-NP_010398.3_EthanolRed 98.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:659991-661112:- gene-YDR113C_FaliES1 rna-NM_001180421.3_FaliES1 cds-NP_010398.3_FaliES1 98.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000002.1:12097-13221:- gene-YDR113C_JAY291 rna-NM_001180421.3_JAY291 cds-NP_010398.3_JAY291 98.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:669413-670534:- gene-YDR113C_MUCL30387 rna-NM_001180421.3_MUCL30387 cds-NP_010398.3_MUCL30387 99.0 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:658432-659553:- gene-YDR113C_MUCL30388 rna-NM_001180421.3_MUCL30388 cds-NP_010398.3_MUCL30388 98.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:643807-644928:- gene-YDR113C_MUCL39482 rna-NM_001180421.3_MUCL39482 cds-NP_010398.3_MUCL39482 98.9 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:581760-582881:- gene-YDR113C_MUCL42920 rna-NM_001180421.3_MUCL42920 cds-NP_010398.3_MUCL42920 99.1 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:680419-681540:- gene-YDR113C_NCIM3186 rna-NM_001180421.3_NCIM3186 cds-NP_010398.3_NCIM3186 98.8 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:643211-644332:- gene-YDR113C_NCYC1407 rna-NM_001180421.3_NCYC1407 cds-NP_010398.3_NCYC1407 98.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:662529-663650:- gene-YDR113C_PE2H3 rna-NM_001180421.3_PE2H3 cds-NP_010398.3_PE2H3 99.0 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:661834-662955:- gene-YDR113C_PE2H4 rna-NM_001180421.3_PE2H4 cds-NP_010398.3_PE2H4 99.0 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:680496-681617:- gene-YDR113C_S288C rna-NM_001180421.3_S288C cds-NP_010398.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000009.1:29145-30266:- gene-YDR113C_SA1 rna-NM_001180421.3_SA1 cds-NP_010398.3_SA1 99.0 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:659513-660634:- gene-YDR113C_ThermosaccDry rna-NM_001180421.3_ThermosaccDry cds-NP_010398.3_ThermosaccDry 98.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:672851-673972:- gene-YDR113C_VR1 rna-NM_001180421.3_VR1 cds-NP_010398.3_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:657099-658220:- gene-YDR113C_ZTW1 rna-NM_001180421.3_ZTW1 cds-NP_010398.3_ZTW1 99.0 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:661538-662665:- gene-YDR113C_Sparadoxus rna-NM_001180421.3_Sparadoxus cds-NP_010398.3_Sparadoxus 85.2 100.0 Verified 1 1 0 False False True False False

Additional files