Gene name: PDR5
Reference locus (S288C): YOR153W
Gene biotype: protein_coding
Description: Pleiotropic ABC efflux transporter of multiple drugs; Plasma membrane ATP-binding cassette (ABC) transporter; multidrug transporter actively regulated by Pdr1p; also involved in steroid transport, cation resistance, and cellular detoxification during exponential growth; PDR5 has a paralog, PDR15, that arose from the whole genome duplication; Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily
Top 10 interactors (score): YOR1 (0.991); PDR3 (0.974); SNQ2 (0.971); PDR1 (0.971); PDR15 (0.966); TPO1 (0.924); QDR1 (0.896); SSZ1 (0.893); ERG6 (0.865); PDR10 (0.855); STE6 (0.846); ERG11 (0.827); PDR16 (0.824); PMA1 (0.822); YAP1 (0.811); RSB1 (0.794); HXT9 (0.79); HXT14 (0.79); HXT11 (0.789); FLR1 (0.783)
Homologues (species, bitscore): ABCG2 (Homo sapiens, 223.8); Abcg2 (Mus musculus, 221.9); abcg2a (Danio rerio, 212.2); abcg2 (Xenopus tropicalis, 218.8); w (Drosophila melanogaster, 198.7); wht-6 (Caenorhabditis elegans, 202.2); ABCG36 (Arabidopsis thaliana, 501.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:617462-621997:+ | gene-YOR153W_AKU4011 | rna-NM_001183572.3_AKU4011 | cds-NP_014796.3_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:19215-23750:+ | gene-YOR153W_BG1 | rna-NM_001183572.3_BG1 | cds-NP_014796.3_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:601532-606067:+ | gene-YOR153W_Bruggeman | rna-NM_001183572.3_Bruggeman | cds-NP_014796.3_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:601551-606086:+ | gene-YOR153W_CAT1 | rna-NM_001183572.3_CAT1 | cds-NP_014796.3_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:599963-604498:+ | gene-YOR153W_CBS1585 | rna-NM_001183572.3_CBS1585 | cds-NP_014796.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:598254-602789:+ | gene-YOR153W_CBS436 | rna-NM_001183572.3_CBS436 | cds-NP_014796.3_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:597575-602110:+ | gene-YOR153W_CBS6412 | rna-NM_001183572.3_CBS6412 | cds-NP_014796.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:606250-610785:+ | gene-YOR153W_CBS6413 | rna-NM_001183572.3_CBS6413 | cds-NP_014796.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:619596-624131:+ | gene-YOR153W_CENPK1137D | rna-NM_001183572.3_CENPK1137D | cds-NP_014796.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:593674-598209:+ | gene-YOR153W_EthanolRed | rna-NM_001183572.3_EthanolRed | cds-NP_014796.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:598527-603062:+ | gene-YOR153W_FaliES1 | rna-NM_001183572.3_FaliES1 | cds-NP_014796.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000070.1:40481-45015:- | gene-YOR153W_JAY291 | rna-NM_001183572.3_JAY291 | cds-NP_014796.3_JAY291 | 99.7 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:606339-610874:+ | gene-YOR153W_MUCL30387 | rna-NM_001183572.3_MUCL30387 | cds-NP_014796.3_MUCL30387 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:613096-617631:+ | gene-YOR153W_MUCL30388 | rna-NM_001183572.3_MUCL30388 | cds-NP_014796.3_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:607804-612339:+ | gene-YOR153W_MUCL39482 | rna-NM_001183572.3_MUCL39482 | cds-NP_014796.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:617222-621757:+ | gene-YOR153W_MUCL42920 | rna-NM_001183572.3_MUCL42920 | cds-NP_014796.3_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:619729-624264:+ | gene-YOR153W_NCIM3186 | rna-NM_001183572.3_NCIM3186 | cds-NP_014796.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:607890-612425:+ | gene-YOR153W_NCYC1407 | rna-NM_001183572.3_NCYC1407 | cds-NP_014796.3_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:606396-610931:+ | gene-YOR153W_PE2H3 | rna-NM_001183572.3_PE2H3 | cds-NP_014796.3_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:616773-621308:+ | gene-YOR153W_PE2H4 | rna-NM_001183572.3_PE2H4 | cds-NP_014796.3_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:619840-624375:+ | gene-YOR153W_S288C | rna-NM_001183572.3_S288C | cds-NP_014796.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:36382-40917:+ | gene-YOR153W_SA1 | rna-NM_001183572.3_SA1 | cds-NP_014796.3_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:597710-602245:+ | gene-YOR153W_ThermosaccDry | rna-NM_001183572.3_ThermosaccDry | cds-NP_014796.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:661396-665931:+ | gene-YOR153W_VR1 | rna-NM_001183572.3_VR1 | cds-NP_014796.3_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:331164-335699:+ | gene-YOR153W_ZTW1 | rna-NM_001183572.3_ZTW1 | cds-NP_014796.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:602839-607374:+ | gene-YOR153W_Sparadoxus | rna-NM_001183572.3_Sparadoxus | cds-NP_014796.3_Sparadoxus | 90.2 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |