Gene name: PDR18
Reference locus (S288C): YNR070W
Gene biotype: protein_coding
Description: Atp-binding cassette, subfamily g (white), member 2, snq2; Putative transporter of the ATP-binding cassette (ABC) family; role in plasma membrane sterol incorporation; implicated in pleiotropic drug resistance; provides resistance to ethanol stress and contributes to a decreased intracellular accumulation of ethanol; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
Top 10 interactors (score): YOR1 (0.884); ZRC1 (0.84); NFT1 (0.789); AZR1 (0.759); YHK8 (0.755); YNR071C (0.75); TPO2 (0.749); YBT1 (0.745); YKR104W (0.745); TPO1 (0.722); FLR1 (0.72); ZRT1 (0.716); PXA2 (0.651); PDR3 (0.617); QDR3 (0.617); PXA1 (0.605); YDR061W (0.593); TPO4 (0.585); TPO3 (0.527); YHR210C (0.525)
Homologues (species, bitscore): ABCG2 (Homo sapiens, 211.8); Abcg2 (Mus musculus, 204.1); abcg2a (Danio rerio, 208.0); abcg2 (Xenopus tropicalis, 214.9); w (Drosophila melanogaster, 190.3); wht-8 (Caenorhabditis elegans, 199.9); ABCG31 (Arabidopsis thaliana, 463.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:182768-186769:- | gene-YNR070W_AKU4011 | rna-NM_001183247.4_AKU4011 | cds-NP_014468.3_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:656946-660947:+ | gene-YNR070W_BG1 | rna-NM_001183247.4_BG1 | cds-NP_014468.3_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:767620-771621:+ | gene-YNR070W_Bruggeman | rna-NM_001183247.4_Bruggeman | cds-NP_014468.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:803527-807529:+ | gene-YNR070W_CAT1 | rna-NM_001183247.4_CAT1 | cds-NP_014468.3_CAT1 | 99.7 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:754407-758408:+ | gene-YNR070W_CBS1585 | rna-NM_001183247.4_CBS1585 | cds-NP_014468.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:817120-821121:+ | gene-YNR070W_CBS436 | rna-NM_001183247.4_CBS436 | cds-NP_014468.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:742877-746878:+ | gene-YNR070W_CBS6412 | rna-NM_001183247.4_CBS6412 | cds-NP_014468.3_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:744932-748933:+ | gene-YNR070W_CBS6413 | rna-NM_001183247.4_CBS6413 | cds-NP_014468.3_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:749734-753735:+ | gene-YNR070W_EthanolRed | rna-NM_001183247.4_EthanolRed | cds-NP_014468.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:741102-745103:+ | gene-YNR070W_FaliES1 | rna-NM_001183247.4_FaliES1 | cds-NP_014468.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000052.1:13007-17008:+ | gene-YNR070W_JAY291 | rna-NM_001183247.4_JAY291 | cds-NP_014468.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | MBVX01000253.1:348-4350:+ | gene-YNR070W_MUCL30387 | rna-NM_001183247.4_MUCL30387 | cds-NP_014468.3_MUCL30387 | 99.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | MBVW01000295.1:368-4370:+ | gene-YNR070W_MUCL30388 | rna-NM_001183247.4_MUCL30388 | cds-NP_014468.3_MUCL30388 | 99.7 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:745736-749737:+ | gene-YNR070W_MUCL39482 | rna-NM_001183247.4_MUCL39482 | cds-NP_014468.3_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:753140-757141:+ | gene-YNR070W_MUCL42920 | rna-NM_001183247.4_MUCL42920 | cds-NP_014468.3_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:765344-769345:+ | gene-YNR070W_NCIM3186 | rna-NM_001183247.4_NCIM3186 | cds-NP_014468.3_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:748321-752322:+ | gene-YNR070W_NCYC1407 | rna-NM_001183247.4_NCYC1407 | cds-NP_014468.3_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:749811-753812:+ | gene-YNR070W_PE2H3 | rna-NM_001183247.4_PE2H3 | cds-NP_014468.3_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:751199-755200:+ | gene-YNR070W_PE2H4 | rna-NM_001183247.4_PE2H4 | cds-NP_014468.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:765375-769376:+ | gene-YNR070W_S288C | rna-NM_001183247.4_S288C | cds-NP_014468.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000087.1:3298-7299:- | gene-YNR070W_SA1 | rna-NM_001183247.4_SA1 | cds-NP_014468.3_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:741445-745446:+ | gene-YNR070W_ThermosaccDry | rna-NM_001183247.4_ThermosaccDry | cds-NP_014468.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:784699-788701:+ | gene-YNR070W_VR1 | rna-NM_001183247.4_VR1 | cds-NP_014468.3_VR1 | 99.8 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:651211-655212:+ | gene-YNR070W_ZTW1 | rna-NM_001183247.4_ZTW1 | cds-NP_014468.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:755412-759413:+ | gene-YNR070W_Sparadoxus | rna-NM_001183247.4_Sparadoxus | cds-NP_014468.3_Sparadoxus | 90.6 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |