PDR15 (YDR406W)


Gene profile

Gene name: PDR15
Reference locus (S288C): YDR406W
Gene biotype: protein_coding

Description: ATP-dependent permease PDR15; Plasma membrane ATP binding cassette (ABC) transporter; multidrug transporter and general stress response factor implicated in cellular detoxification; regulated by Pdr1p, Pdr3p and Pdr8p; promoter contains a PDR responsive element; PDR15 has a paralog, PDR5, that arose from the whole genome duplication; Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily

Top 10 interactors (score): PDR5 (0.966); YOR1 (0.933); PDR3 (0.9); PDR10 (0.86); PDR1 (0.845); TPO1 (0.841); FLR1 (0.809); HXT9 (0.796); HXT14 (0.796); HXT11 (0.795); IPT1 (0.787); DDI1 (0.785); AYT1 (0.746); AZR1 (0.723); VMR1 (0.703); SSZ1 (0.692); YRR1 (0.633); YAP1 (0.619); PDR8 (0.615); YBT1 (0.604)

Homologues (species, bitscore): ABCG2 (Homo sapiens, 217.6); Abcg2 (Mus musculus, 210.3); abcg2a (Danio rerio, 208.8); abcg2 (Xenopus tropicalis, 216.5); w (Drosophila melanogaster, 195.3); wht-6 (Caenorhabditis elegans, 198.7); ABCG30 (Arabidopsis thaliana, 493.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:1219354-1223952:+ gene-YDR406W_AKU4011 rna-NM_001180714.1_AKU4011 cds-NP_010694.1_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000039.1:97837-102435:+ gene-YDR406W_BG1 rna-NM_001180714.1_BG1 cds-NP_010694.1_BG1 99.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1250241-1254830:+ gene-YDR406W_Bruggeman rna-NM_001180714.1_Bruggeman cds-NP_010694.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1228795-1233393:+ gene-YDR406W_CAT1 rna-NM_001180714.1_CAT1 cds-NP_010694.1_CAT1 99.2 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1214274-1218872:+ gene-YDR406W_CBS1585 rna-NM_001180714.1_CBS1585 cds-NP_010694.1_CBS1585 99.1 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1233142-1237731:+ gene-YDR406W_CBS436 rna-NM_001180714.1_CBS436 cds-NP_010694.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1210328-1214926:+ gene-YDR406W_CBS6412 rna-NM_001180714.1_CBS6412 cds-NP_010694.1_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1232183-1236781:+ gene-YDR406W_CBS6413 rna-NM_001180714.1_CBS6413 cds-NP_010694.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1277869-1282458:+ gene-YDR406W_CENPK1137D rna-NM_001180714.1_CENPK1137D cds-NP_010694.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:1223756-1228354:+ gene-YDR406W_EthanolRed rna-NM_001180714.1_EthanolRed cds-NP_010694.1_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1227066-1231664:+ gene-YDR406W_FaliES1 rna-NM_001180714.1_FaliES1 cds-NP_010694.1_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000181.1:23866-28464:- gene-YDR406W_JAY291 rna-NM_001180714.1_JAY291 cds-NP_010694.1_JAY291 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1233803-1238392:+ gene-YDR406W_MUCL30387 rna-NM_001180714.1_MUCL30387 cds-NP_010694.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1215909-1220498:+ gene-YDR406W_MUCL30388 rna-NM_001180714.1_MUCL30388 cds-NP_010694.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1205602-1210200:+ gene-YDR406W_MUCL39482 rna-NM_001180714.1_MUCL39482 cds-NP_010694.1_MUCL39482 99.1 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:1148042-1152631:+ gene-YDR406W_MUCL42920 rna-NM_001180714.1_MUCL42920 cds-NP_010694.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1279133-1283722:+ gene-YDR406W_NCIM3186 rna-NM_001180714.1_NCIM3186 cds-NP_010694.1_NCIM3186 99.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1219574-1224172:+ gene-YDR406W_NCYC1407 rna-NM_001180714.1_NCYC1407 cds-NP_010694.1_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1229706-1234304:+ gene-YDR406W_PE2H3 rna-NM_001180714.1_PE2H3 cds-NP_010694.1_PE2H3 99.2 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1235274-1239872:+ gene-YDR406W_PE2H4 rna-NM_001180714.1_PE2H4 cds-NP_010694.1_PE2H4 99.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1279210-1283799:+ gene-YDR406W_S288C rna-NM_001180714.1_S288C cds-NP_010694.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000071.1:23988-28577:- gene-YDR406W_SA1 rna-NM_001180714.1_SA1 cds-NP_010694.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1231328-1235926:+ gene-YDR406W_ThermosaccDry rna-NM_001180714.1_ThermosaccDry cds-NP_010694.1_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:1246513-1251111:+ gene-YDR406W_VR1 rna-NM_001180714.1_VR1 cds-NP_010694.1_VR1 99.1 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:274132-278721:+ gene-YDR406W_ZTW1 rna-NM_001180714.1_ZTW1 cds-NP_010694.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1226544-1231157:+ gene-YDR406W_Sparadoxus rna-NM_001180714.1_Sparadoxus cds-NP_010694.1_Sparadoxus 90.8 100.0 Verified 1 1 1 False True False False False

Additional files