Gene name: PDR15
Reference locus (S288C): YDR406W
Gene biotype: protein_coding
Description: ATP-dependent permease PDR15; Plasma membrane ATP binding cassette (ABC) transporter; multidrug transporter and general stress response factor implicated in cellular detoxification; regulated by Pdr1p, Pdr3p and Pdr8p; promoter contains a PDR responsive element; PDR15 has a paralog, PDR5, that arose from the whole genome duplication; Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily
Top 10 interactors (score): PDR5 (0.966); YOR1 (0.933); PDR3 (0.9); PDR10 (0.86); PDR1 (0.845); TPO1 (0.841); FLR1 (0.809); HXT9 (0.796); HXT14 (0.796); HXT11 (0.795); IPT1 (0.787); DDI1 (0.785); AYT1 (0.746); AZR1 (0.723); VMR1 (0.703); SSZ1 (0.692); YRR1 (0.633); YAP1 (0.619); PDR8 (0.615); YBT1 (0.604)
Homologues (species, bitscore): ABCG2 (Homo sapiens, 217.6); Abcg2 (Mus musculus, 210.3); abcg2a (Danio rerio, 208.8); abcg2 (Xenopus tropicalis, 216.5); w (Drosophila melanogaster, 195.3); wht-6 (Caenorhabditis elegans, 198.7); ABCG30 (Arabidopsis thaliana, 493.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1219354-1223952:+ | gene-YDR406W_AKU4011 | rna-NM_001180714.1_AKU4011 | cds-NP_010694.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000039.1:97837-102435:+ | gene-YDR406W_BG1 | rna-NM_001180714.1_BG1 | cds-NP_010694.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1250241-1254830:+ | gene-YDR406W_Bruggeman | rna-NM_001180714.1_Bruggeman | cds-NP_010694.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1228795-1233393:+ | gene-YDR406W_CAT1 | rna-NM_001180714.1_CAT1 | cds-NP_010694.1_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1214274-1218872:+ | gene-YDR406W_CBS1585 | rna-NM_001180714.1_CBS1585 | cds-NP_010694.1_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1233142-1237731:+ | gene-YDR406W_CBS436 | rna-NM_001180714.1_CBS436 | cds-NP_010694.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1210328-1214926:+ | gene-YDR406W_CBS6412 | rna-NM_001180714.1_CBS6412 | cds-NP_010694.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1232183-1236781:+ | gene-YDR406W_CBS6413 | rna-NM_001180714.1_CBS6413 | cds-NP_010694.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1277869-1282458:+ | gene-YDR406W_CENPK1137D | rna-NM_001180714.1_CENPK1137D | cds-NP_010694.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1223756-1228354:+ | gene-YDR406W_EthanolRed | rna-NM_001180714.1_EthanolRed | cds-NP_010694.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1227066-1231664:+ | gene-YDR406W_FaliES1 | rna-NM_001180714.1_FaliES1 | cds-NP_010694.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000181.1:23866-28464:- | gene-YDR406W_JAY291 | rna-NM_001180714.1_JAY291 | cds-NP_010694.1_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1233803-1238392:+ | gene-YDR406W_MUCL30387 | rna-NM_001180714.1_MUCL30387 | cds-NP_010694.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1215909-1220498:+ | gene-YDR406W_MUCL30388 | rna-NM_001180714.1_MUCL30388 | cds-NP_010694.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1205602-1210200:+ | gene-YDR406W_MUCL39482 | rna-NM_001180714.1_MUCL39482 | cds-NP_010694.1_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1148042-1152631:+ | gene-YDR406W_MUCL42920 | rna-NM_001180714.1_MUCL42920 | cds-NP_010694.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1279133-1283722:+ | gene-YDR406W_NCIM3186 | rna-NM_001180714.1_NCIM3186 | cds-NP_010694.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1219574-1224172:+ | gene-YDR406W_NCYC1407 | rna-NM_001180714.1_NCYC1407 | cds-NP_010694.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1229706-1234304:+ | gene-YDR406W_PE2H3 | rna-NM_001180714.1_PE2H3 | cds-NP_010694.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1235274-1239872:+ | gene-YDR406W_PE2H4 | rna-NM_001180714.1_PE2H4 | cds-NP_010694.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1279210-1283799:+ | gene-YDR406W_S288C | rna-NM_001180714.1_S288C | cds-NP_010694.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000071.1:23988-28577:- | gene-YDR406W_SA1 | rna-NM_001180714.1_SA1 | cds-NP_010694.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1231328-1235926:+ | gene-YDR406W_ThermosaccDry | rna-NM_001180714.1_ThermosaccDry | cds-NP_010694.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1246513-1251111:+ | gene-YDR406W_VR1 | rna-NM_001180714.1_VR1 | cds-NP_010694.1_VR1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:274132-278721:+ | gene-YDR406W_ZTW1 | rna-NM_001180714.1_ZTW1 | cds-NP_010694.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1226544-1231157:+ | gene-YDR406W_Sparadoxus | rna-NM_001180714.1_Sparadoxus | cds-NP_010694.1_Sparadoxus | 90.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |