Gene name: PDR12
Reference locus (S288C): YPL058C
Gene biotype: protein_coding
Description: ATP-dependent permease PDR12; Plasma membrane ATP-binding cassette (ABC) transporter; weak-acid-inducible multidrug transporter required for weak organic acid resistance; induced by sorbate and benzoate and regulated by War1p; mutants exhibit sorbate hypersensitivity; Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily
Top 10 interactors (score): WAR1 (0.967); YOR1 (0.946); TPO2 (0.852); TPO1 (0.851); HAA1 (0.824); AQR1 (0.763); TPO3 (0.75); AZR1 (0.728); PMA1 (0.715); PDR1 (0.711); QDR2 (0.706); PDR3 (0.694); VMR1 (0.676); QDR3 (0.652); YBT1 (0.644); NFT1 (0.644); PDR16 (0.628); BPT1 (0.624); MSN2 (0.607); FPS1 (0.582)
Homologues (species, bitscore): ABCG2 (Homo sapiens, 196.1); Abcg2 (Mus musculus, 200.3); abcg2a (Danio rerio, 192.2); abcg2 (Xenopus tropicalis, 192.2); w (Drosophila melanogaster, 179.9); wht-2 (Caenorhabditis elegans, 179.5); ABCG36 (Arabidopsis thaliana, 450.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:417342-421877:- | gene-YPL058C_AKU4011 | rna-NM_001183872.1_AKU4011 | cds-NP_015267.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:475554-480089:+ | gene-YPL058C_BG1 | rna-NM_001183872.1_BG1 | cds-NP_015267.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:494300-498835:- | gene-YPL058C_Bruggeman | rna-NM_001183872.1_Bruggeman | cds-NP_015267.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:534016-538551:- | gene-YPL058C_CAT1 | rna-NM_001183872.1_CAT1 | cds-NP_015267.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:421412-425947:- | gene-YPL058C_CBS1585 | rna-NM_001183872.1_CBS1585 | cds-NP_015267.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:435539-440074:- | gene-YPL058C_CBS436 | rna-NM_001183872.1_CBS436 | cds-NP_015267.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:425604-430139:- | gene-YPL058C_CBS6412 | rna-NM_001183872.1_CBS6412 | cds-NP_015267.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:417964-422499:- | gene-YPL058C_CBS6413 | rna-NM_001183872.1_CBS6413 | cds-NP_015267.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:445817-450352:- | gene-YPL058C_CENPK1137D | rna-NM_001183872.1_CENPK1137D | cds-NP_015267.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:415703-420238:- | gene-YPL058C_EthanolRed | rna-NM_001183872.1_EthanolRed | cds-NP_015267.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:423533-428068:- | gene-YPL058C_FaliES1 | rna-NM_001183872.1_FaliES1 | cds-NP_015267.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000283.1:32141-36676:- | gene-YPL058C_JAY291 | rna-NM_001183872.1_JAY291 | cds-NP_015267.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:435232-439767:- | gene-YPL058C_MUCL30387 | rna-NM_001183872.1_MUCL30387 | cds-NP_015267.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:434369-438904:- | gene-YPL058C_MUCL30388 | rna-NM_001183872.1_MUCL30388 | cds-NP_015267.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:414741-419276:- | gene-YPL058C_MUCL39482 | rna-NM_001183872.1_MUCL39482 | cds-NP_015267.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:473333-477868:- | gene-YPL058C_MUCL42920 | rna-NM_001183872.1_MUCL42920 | cds-NP_015267.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:445825-450360:- | gene-YPL058C_NCIM3186 | rna-NM_001183872.1_NCIM3186 | cds-NP_015267.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:422024-426559:- | gene-YPL058C_NCYC1407 | rna-NM_001183872.1_NCYC1407 | cds-NP_015267.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:428633-433168:- | gene-YPL058C_PE2H3 | rna-NM_001183872.1_PE2H3 | cds-NP_015267.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:428251-432786:- | gene-YPL058C_PE2H4 | rna-NM_001183872.1_PE2H4 | cds-NP_015267.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:445842-450377:- | gene-YPL058C_S288C | rna-NM_001183872.1_S288C | cds-NP_015267.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000057.1:61300-65835:- | gene-YPL058C_SA1 | rna-NM_001183872.1_SA1 | cds-NP_015267.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:423333-427868:- | gene-YPL058C_ThermosaccDry | rna-NM_001183872.1_ThermosaccDry | cds-NP_015267.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:438164-442699:- | gene-YPL058C_VR1 | rna-NM_001183872.1_VR1 | cds-NP_015267.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:422642-427177:- | gene-YPL058C_ZTW1 | rna-NM_001183872.1_ZTW1 | cds-NP_015267.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:423322-427857:- | gene-YPL058C_Sparadoxus | rna-NM_001183872.1_Sparadoxus | cds-NP_015267.1_Sparadoxus | 92.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |