Gene name: PDR1
Reference locus (S288C): YGL013C
Gene biotype: protein_coding
Description: Transcription factor that regulates the pleiotropic drug response; zinc cluster protein that is a master regulator involved in recruiting other zinc cluster proteins to pleiotropic drug response elements (PDREs) to fine tune the regulation of multidrug resistance genes; relocalizes to the cytosol in response to hypoxia; PDR1 has a paralog, PDR3, that arose from the whole genome duplication
Top 10 interactors (score): GAL11 (0.984); PDR5 (0.971); SNQ2 (0.958); STB5 (0.955); SSZ1 (0.942); YOR1 (0.94); PDR3 (0.93); YRR1 (0.898); YAP1 (0.881); PDR15 (0.845); ERG3 (0.83); PDR10 (0.813); MSN4 (0.805); RPN4 (0.789); DDI1 (0.781); HXT14 (0.78); HXT9 (0.78); RDR1 (0.78); HXT11 (0.78); IPT1 (0.78)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:471158-474349:- | gene-YGL013C_AKU4011 | rna-NM_001180878.1_AKU4011 | cds-NP_011502.1_AKU4011 | 99.3 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000060.1:101761-104970:+ | gene-YGL013C_BG1 | rna-NM_001180878.1_BG1 | cds-NP_011502.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:472106-475318:- | gene-YGL013C_Bruggeman | rna-NM_001180878.1_Bruggeman | cds-NP_011502.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:470405-473611:- | gene-YGL013C_CAT1 | rna-NM_001180878.1_CAT1 | cds-NP_011502.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:472629-475820:- | gene-YGL013C_CBS1585 | rna-NM_001180878.1_CBS1585 | cds-NP_011502.1_CBS1585 | 99.3 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:466967-470200:- | gene-YGL013C_CBS436 | rna-NM_001180878.1_CBS436 | cds-NP_011502.1_CBS436 | 98.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:465244-468435:- | gene-YGL013C_CBS6412 | rna-NM_001180878.1_CBS6412 | cds-NP_011502.1_CBS6412 | 99.4 | 99.5 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:469300-472491:- | gene-YGL013C_CBS6413 | rna-NM_001180878.1_CBS6413 | cds-NP_011502.1_CBS6413 | 99.5 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:468928-472119:- | gene-YGL013C_CENPK1137D | rna-NM_001180878.1_CENPK1137D | cds-NP_011502.1_CENPK1137D | 99.3 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:459525-462716:- | gene-YGL013C_EthanolRed | rna-NM_001180878.1_EthanolRed | cds-NP_011502.1_EthanolRed | 99.3 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:462763-465972:- | gene-YGL013C_FaliES1 | rna-NM_001180878.1_FaliES1 | cds-NP_011502.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000020.1:1386-4607:- | gene-YGL013C_JAY291 | rna-NM_001180878.1_JAY291 | cds-NP_011502.1_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:469329-472541:- | gene-YGL013C_MUCL30387 | rna-NM_001180878.1_MUCL30387 | cds-NP_011502.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:471878-475090:- | gene-YGL013C_MUCL30388 | rna-NM_001180878.1_MUCL30388 | cds-NP_011502.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:468468-471659:- | gene-YGL013C_MUCL39482 | rna-NM_001180878.1_MUCL39482 | cds-NP_011502.1_MUCL39482 | 99.3 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:477884-481096:- | gene-YGL013C_MUCL42920 | rna-NM_001180878.1_MUCL42920 | cds-NP_011502.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:469092-472298:- | gene-YGL013C_NCIM3186 | rna-NM_001180878.1_NCIM3186 | cds-NP_011502.1_NCIM3186 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:462490-465681:- | gene-YGL013C_NCYC1407 | rna-NM_001180878.1_NCYC1407 | cds-NP_011502.1_NCYC1407 | 99.4 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:465154-468375:- | gene-YGL013C_PE2H3 | rna-NM_001180878.1_PE2H3 | cds-NP_011502.1_PE2H3 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:470204-473425:- | gene-YGL013C_PE2H4 | rna-NM_001180878.1_PE2H4 | cds-NP_011502.1_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:469092-472298:- | gene-YGL013C_S288C | rna-NM_001180878.1_S288C | cds-NP_011502.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000021.1:83286-86495:+ | gene-YGL013C_SA1 | rna-NM_001180878.1_SA1 | cds-NP_011502.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:482088-485297:- | gene-YGL013C_ThermosaccDry | rna-NM_001180878.1_ThermosaccDry | cds-NP_011502.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:572173-575382:- | gene-YGL013C_VR1 | rna-NM_001180878.1_VR1 | cds-NP_011502.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:460712-463903:- | gene-YGL013C_ZTW1 | rna-NM_001180878.1_ZTW1 | cds-NP_011502.1_ZTW1 | 99.4 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:470280-473456:- | gene-YGL013C_Sparadoxus | rna-NM_001180878.1_Sparadoxus | cds-NP_011502.1_Sparadoxus | 88.8 | 98.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |