PDH1 (YPR002W)


Gene profile

Gene name: PDH1
Reference locus (S288C): YPR002W
Gene biotype: protein_coding

Description: Putative 2-methylcitrate dehydratase; mitochondrial protein that participates in respiration; induced by diauxic shift; homologous to E. coli PrpD, may take part in the conversion of 2-methylcitrate to 2-methylisocitrate

Top 10 interactors (score): CIT3 (0.987); ICL2 (0.928); ICL1 (0.82); PDR5 (0.748); PDR1 (0.745); CAT2 (0.745); NPC2 (0.721); CIT2 (0.7); YOR1 (0.699); SNQ2 (0.698); RTA1 (0.697); ERG11 (0.696); CIT1 (0.675); RSB1 (0.671); PDR3 (0.671); ACS1 (0.622); ATF2 (0.615); PUP1 (0.595); IDP2 (0.567); AUS1 (0.526)

Homologues (species, bitscore): Irg1 (Mus musculus, 52.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:529848-531398:+ gene-YPR002W_AKU4011 rna-NM_001184099.1_AKU4011 cds-NP_015326.1_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:365782-367332:- gene-YPR002W_BG1 rna-NM_001184099.1_BG1 cds-NP_015326.1_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:606784-608334:+ gene-YPR002W_Bruggeman rna-NM_001184099.1_Bruggeman cds-NP_015326.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:649528-651078:+ gene-YPR002W_CAT1 rna-NM_001184099.1_CAT1 cds-NP_015326.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:534025-535575:+ gene-YPR002W_CBS1585 rna-NM_001184099.1_CBS1585 cds-NP_015326.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:548108-549658:+ gene-YPR002W_CBS436 rna-NM_001184099.1_CBS436 cds-NP_015326.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:537774-539324:+ gene-YPR002W_CBS6412 rna-NM_001184099.1_CBS6412 cds-NP_015326.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:530485-532035:+ gene-YPR002W_CBS6413 rna-NM_001184099.1_CBS6413 cds-NP_015326.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:558384-559934:+ gene-YPR002W_CENPK1137D rna-NM_001184099.1_CENPK1137D cds-NP_015326.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:528272-529822:+ gene-YPR002W_EthanolRed rna-NM_001184099.1_EthanolRed cds-NP_015326.1_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:536102-537652:+ gene-YPR002W_FaliES1 rna-NM_001184099.1_FaliES1 cds-NP_015326.1_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000341.1:366-1916:- gene-YPR002W_JAY291 rna-NM_001184099.1_JAY291 cds-NP_015326.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:547739-549289:+ gene-YPR002W_MUCL30387 rna-NM_001184099.1_MUCL30387 cds-NP_015326.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:546841-548391:+ gene-YPR002W_MUCL30388 rna-NM_001184099.1_MUCL30388 cds-NP_015326.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:527265-528815:+ gene-YPR002W_MUCL39482 rna-NM_001184099.1_MUCL39482 cds-NP_015326.1_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:586355-587905:+ gene-YPR002W_MUCL42920 rna-NM_001184099.1_MUCL42920 cds-NP_015326.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:558368-559918:+ gene-YPR002W_NCIM3186 rna-NM_001184099.1_NCIM3186 cds-NP_015326.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:534525-536075:+ gene-YPR002W_NCYC1407 rna-NM_001184099.1_NCYC1407 cds-NP_015326.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:541217-542767:+ gene-YPR002W_PE2H3 rna-NM_001184099.1_PE2H3 cds-NP_015326.1_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:540832-542382:+ gene-YPR002W_PE2H4 rna-NM_001184099.1_PE2H4 cds-NP_015326.1_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:558385-559935:+ gene-YPR002W_S288C rna-NM_001184099.1_S288C cds-NP_015326.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000076.1:55126-56676:+ gene-YPR002W_SA1 rna-NM_001184099.1_SA1 cds-NP_015326.1_SA1 99.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:535901-537451:+ gene-YPR002W_ThermosaccDry rna-NM_001184099.1_ThermosaccDry cds-NP_015326.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:551301-552851:+ gene-YPR002W_VR1 rna-NM_001184099.1_VR1 cds-NP_015326.1_VR1 99.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:535206-536756:+ gene-YPR002W_ZTW1 rna-NM_001184099.1_ZTW1 cds-NP_015326.1_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:534885-536435:+ gene-YPR002W_Sparadoxus rna-NM_001184099.1_Sparadoxus cds-NP_015326.1_Sparadoxus 89.7 100.0 Verified 1 1 1 False True False False False

Additional files