PDE2 (YOR360C)


Gene profile

Gene name: PDE2
Reference locus (S288C): YOR360C
Gene biotype: protein_coding

Description: 3',5'-cyclic-nucleotide phosphodiesterase 2; High-affinity cyclic AMP phosphodiesterase; component of the cAMP-dependent protein kinase signaling system, protects the cell from extracellular cAMP, contains readthrough motif surrounding termination codon

Top 10 interactors (score): PDE1 (0.999); CYR1 (0.998); BCY1 (0.986); TPK2 (0.985); TPK1 (0.984); TPK3 (0.982); RAS2 (0.975); GPA2 (0.966); MDN1 (0.962); IRA2 (0.939); ADE13 (0.923); ADO1 (0.923); GUK1 (0.921); GUA1 (0.901); ADK1 (0.901); HAM1 (0.901); ADK2 (0.901); FAP7 (0.9); APT1 (0.9); AMD1 (0.9)

Homologues (species, bitscore): PDE9A (Homo sapiens, 89.0); Pde9a (Mus musculus, 84.7); pde8b (Danio rerio, 87.8); pde4b (Xenopus tropicalis, 84.3); Pde8 (Drosophila melanogaster, 83.6); pde-6 (Caenorhabditis elegans, 94.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:999822-1001402:- gene-YOR360C_AKU4011 rna-NM_001183780.1_AKU4011 cds-NP_015005.1_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000078.1:36997-38577:- gene-YOR360C_BG1 rna-NM_001183780.1_BG1 cds-NP_015005.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:984641-986221:- gene-YOR360C_Bruggeman rna-NM_001183780.1_Bruggeman cds-NP_015005.1_Bruggeman 99.6 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:984469-986049:- gene-YOR360C_CAT1 rna-NM_001183780.1_CAT1 cds-NP_015005.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:984232-985812:- gene-YOR360C_CBS1585 rna-NM_001183780.1_CBS1585 cds-NP_015005.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:979052-980632:- gene-YOR360C_CBS436 rna-NM_001183780.1_CBS436 cds-NP_015005.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:213534-215109:- gene-YOR360C_CBS6412 rna-NM_001183780.1_CBS6412 cds-NP_015005.1_CBS6412 99.4 99.6 Unannotated 1 1 0 False False False True False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:988505-990085:- gene-YOR360C_CBS6413 rna-NM_001183780.1_CBS6413 cds-NP_015005.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:1013063-1014643:- gene-YOR360C_CENPK1137D rna-NM_001183780.1_CENPK1137D cds-NP_015005.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:228531-230111:- gene-YOR360C_EthanolRed rna-NM_001183780.1_EthanolRed cds-NP_015005.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:981360-982940:- gene-YOR360C_FaliES1 rna-NM_001183780.1_FaliES1 cds-NP_015005.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000078.1:22735-24315:+ gene-YOR360C_JAY291 rna-NM_001183780.1_JAY291 cds-NP_015005.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:993967-995547:- gene-YOR360C_MUCL30387 rna-NM_001183780.1_MUCL30387 cds-NP_015005.1_MUCL30387 99.6 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:1001994-1003574:- gene-YOR360C_MUCL30388 rna-NM_001183780.1_MUCL30388 cds-NP_015005.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:990767-992347:- gene-YOR360C_MUCL39482 rna-NM_001183780.1_MUCL39482 cds-NP_015005.1_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:998373-999953:- gene-YOR360C_MUCL42920 rna-NM_001183780.1_MUCL42920 cds-NP_015005.1_MUCL42920 99.6 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:1013130-1014710:- gene-YOR360C_NCIM3186 rna-NM_001183780.1_NCIM3186 cds-NP_015005.1_NCIM3186 92.0 100.0 Verified 1 1 0 False False False True False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:991775-993355:- gene-YOR360C_NCYC1407 rna-NM_001183780.1_NCYC1407 cds-NP_015005.1_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:987034-988614:- gene-YOR360C_PE2H3 rna-NM_001183780.1_PE2H3 cds-NP_015005.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:1003385-1004965:- gene-YOR360C_PE2H4 rna-NM_001183780.1_PE2H4 cds-NP_015005.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:1013241-1014821:- gene-YOR360C_S288C rna-NM_001183780.1_S288C cds-NP_015005.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000016.1:117768-119348:- gene-YOR360C_SA1 rna-NM_001183780.1_SA1 cds-NP_015005.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:980530-982110:- gene-YOR360C_ThermosaccDry rna-NM_001183780.1_ThermosaccDry cds-NP_015005.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:1041787-1043367:- gene-YOR360C_VR1 rna-NM_001183780.1_VR1 cds-NP_015005.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:713260-714840:- gene-YOR360C_ZTW1 rna-NM_001183780.1_ZTW1 cds-NP_015005.1_ZTW1 99.6 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:986714-988294:- gene-YOR360C_Sparadoxus rna-NM_001183780.1_Sparadoxus cds-NP_015005.1_Sparadoxus 92.8 100.0 Verified 1 1 1 False True False False False

Additional files