PDE1 (YGL248W)


Gene profile

Gene name: PDE1
Reference locus (S288C): YGL248W
Gene biotype: protein_coding

Description: 3',5'-cyclic-nucleotide phosphodiesterase 1; Low-affinity cyclic AMP phosphodiesterase; controls glucose and intracellular acidification-induced cAMP signaling, target of the cAMP-protein kinase A (PKA) pathway; glucose induces transcription and inhibits translation

Top 10 interactors (score): PDE2 (0.999); CYR1 (0.996); BCY1 (0.961); GPA2 (0.935); TPK1 (0.907); AMD1 (0.903); HAM1 (0.903); YND1 (0.9); ADO1 (0.9); FAP7 (0.9); ADK2 (0.9); ADK1 (0.9); HPT1 (0.9); ADE13 (0.9); APT1 (0.9); GUA1 (0.9); GUK1 (0.9); IRA2 (0.9); APT2 (0.9); TPK2 (0.883)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:37178-38287:+ gene-YGL248W_AKU4011 rna-NM_001181114.1_AKU4011 cds-NP_011266.1_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000175.1:29217-30326:+ gene-YGL248W_BG1 rna-NM_001181114.1_BG1 cds-NP_011266.1_BG1 99.0 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:37533-38642:+ gene-YGL248W_Bruggeman rna-NM_001181114.1_Bruggeman cds-NP_011266.1_Bruggeman 99.4 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:35605-36714:+ gene-YGL248W_CAT1 rna-NM_001181114.1_CAT1 cds-NP_011266.1_CAT1 99.0 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:41466-42575:+ gene-YGL248W_CBS1585 rna-NM_001181114.1_CBS1585 cds-NP_011266.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:36194-37303:+ gene-YGL248W_CBS436 rna-NM_001181114.1_CBS436 cds-NP_011266.1_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:29034-30143:+ gene-YGL248W_CBS6412 rna-NM_001181114.1_CBS6412 cds-NP_011266.1_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:35322-36431:+ gene-YGL248W_CBS6413 rna-NM_001181114.1_CBS6413 cds-NP_011266.1_CBS6413 99.1 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:35315-36424:+ gene-YGL248W_CENPK1137D rna-NM_001181114.1_CENPK1137D cds-NP_011266.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:28455-29564:+ gene-YGL248W_EthanolRed rna-NM_001181114.1_EthanolRed cds-NP_011266.1_EthanolRed 99.4 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:28816-29925:+ gene-YGL248W_FaliES1 rna-NM_001181114.1_FaliES1 cds-NP_011266.1_FaliES1 99.4 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000079.1:37156-38265:- gene-YGL248W_JAY291 rna-NM_001181114.1_JAY291 cds-NP_011266.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:37470-38579:+ gene-YGL248W_MUCL30387 rna-NM_001181114.1_MUCL30387 cds-NP_011266.1_MUCL30387 99.3 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:39623-40732:+ gene-YGL248W_MUCL30388 rna-NM_001181114.1_MUCL30388 cds-NP_011266.1_MUCL30388 99.6 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:38063-39172:+ gene-YGL248W_MUCL39482 rna-NM_001181114.1_MUCL39482 cds-NP_011266.1_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:40956-42065:+ gene-YGL248W_MUCL42920 rna-NM_001181114.1_MUCL42920 cds-NP_011266.1_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:35653-36762:+ gene-YGL248W_NCIM3186 rna-NM_001181114.1_NCIM3186 cds-NP_011266.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:29827-30936:+ gene-YGL248W_NCYC1407 rna-NM_001181114.1_NCYC1407 cds-NP_011266.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:31683-32792:+ gene-YGL248W_PE2H3 rna-NM_001181114.1_PE2H3 cds-NP_011266.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:31231-32340:+ gene-YGL248W_PE2H4 rna-NM_001181114.1_PE2H4 cds-NP_011266.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:35653-36762:+ gene-YGL248W_S288C rna-NM_001181114.1_S288C cds-NP_011266.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000002.1:338572-339681:- gene-YGL248W_SA1 rna-NM_001181114.1_SA1 cds-NP_011266.1_SA1 99.0 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:29131-30240:+ gene-YGL248W_ThermosaccDry rna-NM_001181114.1_ThermosaccDry cds-NP_011266.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:36120-37229:+ gene-YGL248W_VR1 rna-NM_001181114.1_VR1 cds-NP_011266.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000014.1:28204-29313:+ gene-YGL248W_ZTW1 rna-NM_001181114.1_ZTW1 cds-NP_011266.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:36876-37985:+ gene-YGL248W_Sparadoxus rna-NM_001181114.1_Sparadoxus cds-NP_011266.1_Sparadoxus 90.9 100.0 Verified 1 1 1 False True False False False

Additional files