Gene name: PDC6
Reference locus (S288C): YGR087C
Gene biotype: protein_coding
Description: Minor isoform of pyruvate decarboxylase; decarboxylates pyruvate to acetaldehyde, involved in amino acid catabolism; transcription is glucose- and ethanol-dependent, and is strongly induced during sulfur limitation; Belongs to the TPP enzyme family
Top 10 interactors (score): PDC1 (0.999); PDC5 (0.999); ADH4 (0.977); ARO9 (0.977); ARO8 (0.976); PYK2 (0.976); SFA1 (0.976); ADH1 (0.972); ALD6 (0.971); BAT2 (0.971); ADH2 (0.969); CDC19 (0.964); ADH3 (0.957); BDH1 (0.949); ADH6 (0.948); PDB1 (0.946); PDA1 (0.94); ADH5 (0.934); TAL1 (0.926); MAE1 (0.911)
Homologues (species, bitscore): HACL1 (Homo sapiens, 94.0); Hacl1 (Mus musculus, 93.2); hacl1 (Danio rerio, 89.0); hacl1 (Xenopus tropicalis, 92.4); CG11208 (Drosophila melanogaster, 90.1); B0334.3 (Caenorhabditis elegans, 96.3); PDC3 (Arabidopsis thaliana, 297.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:635473-637164:- | gene-YGR087C_AKU4011 | rna-NM_001181216.3_AKU4011 | cds-NP_011601.3_AKU4011 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000173.1:71267-72958:- | gene-YGR087C_BG1 | rna-NM_001181216.3_BG1 | cds-NP_011601.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:637407-639098:- | gene-YGR087C_Bruggeman | rna-NM_001181216.3_Bruggeman | cds-NP_011601.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:635851-637542:- | gene-YGR087C_CAT1 | rna-NM_001181216.3_CAT1 | cds-NP_011601.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:636437-638128:- | gene-YGR087C_CBS1585 | rna-NM_001181216.3_CBS1585 | cds-NP_011601.3_CBS1585 | 98.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:638096-639787:- | gene-YGR087C_CBS436 | rna-NM_001181216.3_CBS436 | cds-NP_011601.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:628130-629821:- | gene-YGR087C_CBS6412 | rna-NM_001181216.3_CBS6412 | cds-NP_011601.3_CBS6412 | 98.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:633072-634763:- | gene-YGR087C_CBS6413 | rna-NM_001181216.3_CBS6413 | cds-NP_011601.3_CBS6413 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:650972-652663:- | gene-YGR087C_CENPK1137D | rna-NM_001181216.3_CENPK1137D | cds-NP_011601.3_CENPK1137D | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:623016-624708:- | gene-YGR087C_EthanolRed | rna-NM_001181216.3_EthanolRed | cds-NP_011601.3_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:626863-628555:- | gene-YGR087C_FaliES1 | rna-NM_001181216.3_FaliES1 | cds-NP_011601.3_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000396.1:47996-49687:+ | gene-YGR087C_JAY291 | rna-NM_001181216.3_JAY291 | cds-NP_011601.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:634113-635804:- | gene-YGR087C_MUCL30387 | rna-NM_001181216.3_MUCL30387 | cds-NP_011601.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:637458-639149:- | gene-YGR087C_MUCL30388 | rna-NM_001181216.3_MUCL30388 | cds-NP_011601.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:632165-633856:- | gene-YGR087C_MUCL39482 | rna-NM_001181216.3_MUCL39482 | cds-NP_011601.3_MUCL39482 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:642452-644143:- | gene-YGR087C_MUCL42920 | rna-NM_001181216.3_MUCL42920 | cds-NP_011601.3_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:651290-652981:- | gene-YGR087C_NCIM3186 | rna-NM_001181216.3_NCIM3186 | cds-NP_011601.3_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:626854-628545:- | gene-YGR087C_NCYC1407 | rna-NM_001181216.3_NCYC1407 | cds-NP_011601.3_NCYC1407 | 98.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:629540-631231:- | gene-YGR087C_PE2H3 | rna-NM_001181216.3_PE2H3 | cds-NP_011601.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:634660-636351:- | gene-YGR087C_PE2H4 | rna-NM_001181216.3_PE2H4 | cds-NP_011601.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:651290-652981:- | gene-YGR087C_S288C | rna-NM_001181216.3_S288C | cds-NP_011601.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000015.1:77864-79555:- | gene-YGR087C_SA1 | rna-NM_001181216.3_SA1 | cds-NP_011601.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:646537-648229:- | gene-YGR087C_ThermosaccDry | rna-NM_001181216.3_ThermosaccDry | cds-NP_011601.3_ThermosaccDry | 98.9 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:743729-745420:- | gene-YGR087C_VR1 | rna-NM_001181216.3_VR1 | cds-NP_011601.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000015.1:101488-103179:- | gene-YGR087C_ZTW1 | rna-NM_001181216.3_ZTW1 | cds-NP_011601.3_ZTW1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:636718-638409:- | gene-YGR087C_Sparadoxus | rna-NM_001181216.3_Sparadoxus | cds-NP_011601.3_Sparadoxus | 89.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |