Gene name: PDC5
Reference locus (S288C): YLR134W
Gene biotype: protein_coding
Description: Pyruvate decarboxylase isozyme 2; Minor isoform of pyruvate decarboxylase; key enzyme in alcoholic fermentation, decarboxylates pyruvate to acetaldehyde, regulation is glucose- and ethanol-dependent, repressed by thiamine, involved in amino acid catabolism
Top 10 interactors (score): PDC6 (0.999); PDC1 (0.999); CDC19 (0.988); ADH1 (0.981); SFA1 (0.976); ARO9 (0.976); ARO8 (0.975); ADH4 (0.972); ALD6 (0.971); FBA1 (0.97); BAT2 (0.969); PYK2 (0.969); ADH2 (0.964); PDB1 (0.941); ADH5 (0.941); BDH1 (0.939); ADH3 (0.939); PDA1 (0.934); ENO2 (0.933); ENO1 (0.913)
Homologues (species, bitscore): HACL1 (Homo sapiens, 96.7); Hacl1 (Mus musculus, 97.4); hacl1 (Danio rerio, 89.7); hacl1 (Xenopus tropicalis, 97.1); CG11208 (Drosophila melanogaster, 92.4); B0334.3 (Caenorhabditis elegans, 87.8); AT5G01320 (Arabidopsis thaliana, 302.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:393203-394894:+ | gene-YLR134W_AKU4011 | rna-NM_001182021.1_AKU4011 | cds-NP_013235.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:356987-358678:+ | gene-YLR134W_BG1 | rna-NM_001182021.1_BG1 | cds-NP_013235.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:405086-406777:+ | gene-YLR134W_Bruggeman | rna-NM_001182021.1_Bruggeman | cds-NP_013235.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:404496-406187:+ | gene-YLR134W_CAT1 | rna-NM_001182021.1_CAT1 | cds-NP_013235.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:400347-402038:+ | gene-YLR134W_CBS1585 | rna-NM_001182021.1_CBS1585 | cds-NP_013235.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:390587-392278:+ | gene-YLR134W_CBS436 | rna-NM_001182021.1_CBS436 | cds-NP_013235.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:398764-400455:+ | gene-YLR134W_CBS6412 | rna-NM_001182021.1_CBS6412 | cds-NP_013235.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:400612-402303:+ | gene-YLR134W_CBS6413 | rna-NM_001182021.1_CBS6413 | cds-NP_013235.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:395745-397435:+ | gene-YLR134W_CENPK1137D | rna-NM_001182021.1_CENPK1137D | cds-NP_013235.1_CENPK1137D | 82.4 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:393404-395095:+ | gene-YLR134W_EthanolRed | rna-NM_001182021.1_EthanolRed | cds-NP_013235.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:392915-394606:+ | gene-YLR134W_FaliES1 | rna-NM_001182021.1_FaliES1 | cds-NP_013235.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000061.1:1-1282:+ | gene-YLR134W_JAY291 | rna-NM_001182021.1_JAY291 | cds-NP_013235.1_JAY291 | 75.7 | 75.7 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:405078-406769:+ | gene-YLR134W_MUCL30387 | rna-NM_001182021.1_MUCL30387 | cds-NP_013235.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:409896-411587:+ | gene-YLR134W_MUCL30388 | rna-NM_001182021.1_MUCL30388 | cds-NP_013235.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:400856-402547:+ | gene-YLR134W_MUCL39482 | rna-NM_001182021.1_MUCL39482 | cds-NP_013235.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:400986-402677:+ | gene-YLR134W_MUCL42920 | rna-NM_001182021.1_MUCL42920 | cds-NP_013235.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:410697-412388:+ | gene-YLR134W_NCIM3186 | rna-NM_001182021.1_NCIM3186 | cds-NP_013235.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:393128-394819:+ | gene-YLR134W_NCYC1407 | rna-NM_001182021.1_NCYC1407 | cds-NP_013235.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:398697-400388:+ | gene-YLR134W_PE2H3 | rna-NM_001182021.1_PE2H3 | cds-NP_013235.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:398438-400129:+ | gene-YLR134W_PE2H4 | rna-NM_001182021.1_PE2H4 | cds-NP_013235.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:410723-412414:+ | gene-YLR134W_S288C | rna-NM_001182021.1_S288C | cds-NP_013235.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000055.1:36634-38325:+ | gene-YLR134W_SA1 | rna-NM_001182021.1_SA1 | cds-NP_013235.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:394125-395816:+ | gene-YLR134W_ThermosaccDry | rna-NM_001182021.1_ThermosaccDry | cds-NP_013235.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:406838-408529:+ | gene-YLR134W_VR1 | rna-NM_001182021.1_VR1 | cds-NP_013235.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:391923-393614:+ | gene-YLR134W_ZTW1 | rna-NM_001182021.1_ZTW1 | cds-NP_013235.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:402023-403714:+ | gene-YLR134W_Sparadoxus | rna-NM_001182021.1_Sparadoxus | cds-NP_013235.1_Sparadoxus | 95.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |