Gene name: PDC2
Reference locus (S288C): YDR081C
Gene biotype: protein_coding
Description: Protein PDC2; Transcription factor for thiamine-regulated genes; required for expression of the two isoforms of pyruvate decarboxylase (PDC1 and PDC5) along with thiamine biosynthetic genes; binds a DNA sequence in the PDC5 promoter; mutant fails to grow on 2% glucose and thus is scored as inviable under standard conditions
Top 10 interactors (score): THI3 (0.967); THI2 (0.919); PMU1 (0.844); THI4 (0.821); THI20 (0.808); PDC5 (0.779); PDC1 (0.775); STN1 (0.767); RLI1 (0.754); THI7 (0.749); YLR177W (0.745); DBF4 (0.737); LCB2 (0.732); EGH1 (0.71); THI74 (0.699); TPN1 (0.697); THI6 (0.674); EDS1 (0.652); THI80 (0.65); SLU7 (0.617)
Homologues (species, bitscore): TIGD4 (Homo sapiens, 79.3); Tigd4 (Mus musculus, 79.0); TIGD6 (Xenopus tropicalis, 84.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:584865-587642:- | gene-YDR081C_AKU4011 | rna-NM_001180389.1_AKU4011 | cds-NP_010366.1_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:537678-540455:+ | gene-YDR081C_BG1 | rna-NM_001180389.1_BG1 | cds-NP_010366.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:617093-619870:- | gene-YDR081C_Bruggeman | rna-NM_001180389.1_Bruggeman | cds-NP_010366.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:600732-603509:- | gene-YDR081C_CAT1 | rna-NM_001180389.1_CAT1 | cds-NP_010366.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:575884-578661:- | gene-YDR081C_CBS1585 | rna-NM_001180389.1_CBS1585 | cds-NP_010366.1_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:600899-603676:- | gene-YDR081C_CBS436 | rna-NM_001180389.1_CBS436 | cds-NP_010366.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:572299-575076:- | gene-YDR081C_CBS6412 | rna-NM_001180389.1_CBS6412 | cds-NP_010366.1_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:600829-603606:- | gene-YDR081C_CBS6413 | rna-NM_001180389.1_CBS6413 | cds-NP_010366.1_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:606349-609126:- | gene-YDR081C_CENPK1137D | rna-NM_001180389.1_CENPK1137D | cds-NP_010366.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:586656-589433:- | gene-YDR081C_EthanolRed | rna-NM_001180389.1_EthanolRed | cds-NP_010366.1_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:593450-596227:- | gene-YDR081C_FaliES1 | rna-NM_001180389.1_FaliES1 | cds-NP_010366.1_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000358.1:35043-37820:+ | gene-YDR081C_JAY291 | rna-NM_001180389.1_JAY291 | cds-NP_010366.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:601710-604487:- | gene-YDR081C_MUCL30387 | rna-NM_001180389.1_MUCL30387 | cds-NP_010366.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:592022-594799:- | gene-YDR081C_MUCL30388 | rna-NM_001180389.1_MUCL30388 | cds-NP_010366.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:577254-580031:- | gene-YDR081C_MUCL39482 | rna-NM_001180389.1_MUCL39482 | cds-NP_010366.1_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:507830-510607:- | gene-YDR081C_MUCL42920 | rna-NM_001180389.1_MUCL42920 | cds-NP_010366.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:607227-610004:- | gene-YDR081C_NCIM3186 | rna-NM_001180389.1_NCIM3186 | cds-NP_010366.1_NCIM3186 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:576161-578938:- | gene-YDR081C_NCYC1407 | rna-NM_001180389.1_NCYC1407 | cds-NP_010366.1_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:595628-598405:- | gene-YDR081C_PE2H3 | rna-NM_001180389.1_PE2H3 | cds-NP_010366.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:594933-597710:- | gene-YDR081C_PE2H4 | rna-NM_001180389.1_PE2H4 | cds-NP_010366.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:607304-610081:- | gene-YDR081C_S288C | rna-NM_001180389.1_S288C | cds-NP_010366.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000011.1:35254-38031:+ | gene-YDR081C_SA1 | rna-NM_001180389.1_SA1 | cds-NP_010366.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:592980-595757:- | gene-YDR081C_ThermosaccDry | rna-NM_001180389.1_ThermosaccDry | cds-NP_010366.1_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:605528-608305:- | gene-YDR081C_VR1 | rna-NM_001180389.1_VR1 | cds-NP_010366.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:590564-593341:- | gene-YDR081C_ZTW1 | rna-NM_001180389.1_ZTW1 | cds-NP_010366.1_ZTW1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:595224-598037:- | gene-YDR081C_Sparadoxus | rna-NM_001180389.1_Sparadoxus | cds-NP_010366.1_Sparadoxus | 88.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |